Release 4 4B

This page is part of the FHIR Specification (v4.0.1: R4 (v4.3.0: R4B - Mixed Normative and STU ) in it's permanent home (it will always be available at this URL). ). The current version which supercedes this version is 5.0.0 . For a full list of available versions, see the Directory of published versions . Page versions: R5 R4B R4 R4B R4

14.9 14.10 Resource Evidence - Content

Clinical Decision Support Work Group Maturity Level : 0 1   Trial Use Security Category : Business Compartments : Not linked to any defined compartments

The Evidence resource describes Resource provides a machine-interpretable expression of an evidence concept including the conditional state (population and any exposures being compared within evidence variables (eg population, exposures/interventions, comparators, outcomes, measured variables, confounding variables), the population) statistics, and outcome (if specified) that the knowledge (evidence, assertion, recommendation) is about. certainty of this evidence.

14.9.1 14.10.1 Scope and Usage

The scope Evidence Resource enables the expression of the Evidence resource is to describe most granular form of evidence, such as the conditional state (population and exposures being considered or compared within actual quantitative results of a population) with study or without scientific analysis.

Human-readable summaries of the outcomes that knowledge (evidence, Evidence Resource may be expressed in description, assertion, recommendation) and note elements. The description element is about. typically used for the primary expression. The Evidence resource assertion element is a less commonly bundled series used and is typically used for interpretive expression. The note element may be used for any number of evidence variables from explanatory, variant, or related comments.

The variableDefinition element is used to describe what the "PICO" specification of medical knowledge: Population - evidence is about. Each variable defined must be assigned a variable role which signals how that variable is used in the population statistics within which exposures the Evidence Resource. The variable definition may be expressed in human-readable form (with a description element) and/or expressed in computable form by referencing Group or EvidenceVariable Resources. In general, Group Resources are used to define populations and outcomes EvidenceVariable Resources are being considered Intervention - used to define exposures and measured variables. The variableDefinition elements allows expression of the conditional state or exposure state being described for which one is expressing observed variable and the risk intended variable. In many forms of or effect on an outcome Comparison - expression the alternative conditional state or alternative exposure state when one Evidence is comparing states interpreted for a specific context and recognition of both observed and intended variables is important for understanding the effect on an outcome Outcome - applicability and certainty of the result or effect evidence.

The heart of an intervention or exposure in a population PICO (and its variants like PECO or PICOT) the evidence is the statistic. The statistic BackboneElement provides a universal acronym used in evidence-based medicine communities to clearly express research questions machine-interpretable expression of a statistic, including the quantity; unit of measure; classification of statistic type; sample size; attributes such as confidence intervals, p values, and heterogeneity estimates; and statistic model characteristics. An Evidence Resource may contain more than one statistic, in which case each statistic matches the same combination of variable definitions.

Because a statistic can rarely be interpreted without knowing how it was obtained, the Evidence Resource enables expression of the studyType . For evidence findings. The derived from synthesis of evidence, the Evidence resource allows Resource enables expression of the higher-order concept for recommendations synthesisType .

The certainty Element provides a machine-interpretable expression of certainty, confidence or quality of the resource in healthcare where multiple outcomes are considered, which it is included. The certainty Element can express overall certainty and certainty of any subcomponent concepts using codeable concepts from structured rating systems. The certainty Element enables machine-to-machine communication of the higher-order concept/combination for framing research questions. certainty of evidence.

14.9.2

14.10.2 Boundaries and Relationships

The Evidence resource references Resource is the central atomic component for the Evidence-related Resources. The Evidence Resource may reference multiple Group and EvidenceVariable resource two or more times Resources; in these cases, the Group and EvidenceVariable Resources to which an Evidence Resource points does not refer back to clearly specify the relationship among Evidence. In the context of evidence variable concepts in framing a research question, synthesis, an EvidenceVariable Resource may reference Evidence Resources where the EvidenceVariable Resource is used to define the set of evidence assertion, or recommendation. being synthesized.

14.10.3 References

No resources refer to this resource directly.

This resource does not implement any patterns.

14.9.3 14.10.4 Resource Content

Structure

Name Flags Card. Type Description & Constraints doco
. . Evidence I TU DomainResource A research context or question Single evidence bit
+ Warning: Name should be usable as an identifier for the module by machine processing applications such as code generation
Elements defined in Ancestors: id , meta , implicitRules , language , text , contained , extension , modifierExtension
. . . url Σ 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI (globally unique)
. . . identifier Σ 0..* Identifier Additional identifier for the evidence summary
. . . version Σ 0..1 string Business version of the evidence this summary
. . title . citeAs[x] Σ 0..1 string Name Citation for this evidence (human friendly)
. shortTitle . . . citeAsReference 0..1 string Reference ( Citation ) Title for use in informal contexts
. . subtitle . . citeAsMarkdown 0..1 string markdown Subordinate title of the Evidence
. . . status ?! Σ 1..1 code draft | active | retired | unknown
PublicationStatus ( Required )
. . . date Σ 0..1 dateTime Date last changed
. . . useContext Σ 0..* UsageContext The context that the content is intended to support
... approvalDate 0..1 date When the summary was approved by publisher
. . . lastReviewDate 0..1 date When the summary was last reviewed
... publisher Σ 0..1 string Name of the publisher (organization or individual)
. . . contact Σ 0..* ContactDetail Contact details for the publisher
. . . author Σ 0..* ContactDetail Who authored the content
... editor 0..* ContactDetail Who edited the content
... reviewer 0..* ContactDetail Who reviewed the content
... endorser Σ 0..* ContactDetail Who endorsed the content
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary
. . . description Σ 0..1 markdown Description of the particular summary
... assertion 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes
... variableDefinition 1..* BackboneElement Evidence variable such as population, exposure, or outcome
.... description 0..1 markdown Natural language A text description or summary of the evidence variable
. . . . note 0..* Annotation Used for footnotes or Footnotes and/or explanatory notes
. . . . useContext variableRole Σ 0..* 1..1 UsageContext CodeableConcept The context that population | subpopulation | exposure | referenceExposure | measuredVariable | confounder
EvidenceVariableRole ( Extensible )
.... observed Σ 0..1 Reference ( Group | EvidenceVariable ) Definition of the actual variable related to the statistic(s)
.... intended 0..1 Reference ( Group | EvidenceVariable ) Definition of the content is intended variable related to support the Evidence
.... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
EvidenceDirectness ( Extensible )
. . . synthesisType 0..1 CodeableConcept The method to combine studies
SynthesisType ( Extensible )
. . . jurisdiction studyType Σ 0..* 0..1 CodeableConcept Intended jurisdiction for The type of study that produced this evidence (if applicable)
Jurisdiction StudyType ( Extensible )
. . . statistic 0..* BackboneElement Values and parameters for a single statistic
. . . copyright . description 0..1 string Description of content
.... note 0..1 0..* markdown Annotation Use Footnotes and/or publishing restrictions explanatory notes
. . . approvalDate . statisticType 0..1 date CodeableConcept When the evidence was approved by publisher Type of statistic, eg relative risk
StatisticType ( Extensible )
. . . lastReviewDate . category 0..1 date CodeableConcept When the evidence was last reviewed Associated category for categorical variable
. . . . effectivePeriod quantity Σ 0..1 Quantity Statistic value
.... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
.... numberAffected 0..1 Period unsignedInt When The number of participants affected
.... sampleSize 0..1 BackboneElement Number of samples in the evidence is expected to be used statistic
. . . . . description 0..1 string Textual description of sample size for statistic
... . . topic note 0..* CodeableConcept Annotation The category of Footnote or explanatory note about the Evidence, such as Education, Treatment, Assessment, etc. sample size
DefinitionTopic
. . . . . numberOfStudies ( Example ) 0..1 unsignedInt Number of contributing studies
. . . . author . numberOfParticipants 0..1 unsignedInt Cumulative number of participants
..... knownDataCount 0..* 0..1 ContactDetail unsignedInt Who authored Number of participants with known results for measured variables
.... attributeEstimate 0..* BackboneElement An attribute of the content Statistic
. . . . . description 0..1 string Textual description of the attribute estimate
... . . editor note 0..* ContactDetail Annotation Who edited Footnote or explanatory note about the content estimate
. . . . . reviewer type 0..* 0..1 ContactDetail CodeableConcept Who reviewed the content The type of attribute estimate, eg confidence interval or p value
AttributeEstimateType ( Extensible )
. . . . . endorser quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
..... level 0..1 decimal Level of confidence interval, eg 0.95 for 95% confidence interval
..... range 0..1 Range Lower and upper bound values of the attribute estimate
..... attributeEstimate 0..* see attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate
.... modelCharacteristic ContactDetail 0..* BackboneElement Who endorsed An aspect of the content statistical model
. . . . . relatedArtifact code 0..* 1..1 RelatedArtifact CodeableConcept Additional documentation, citations, etc. Model specification
StatisticModelCode ( Extensible )
. . . . exposureBackground . value Σ 0..1 SimpleQuantity Numerical value to complete model specification
..... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
...... variableDefinition 1..1 Reference ( Group | EvidenceVariable ) What population? Description of the variable
. . . . . exposureVariant . handling Σ 0..1 0..* code continuous | dichotomous | ordinal | polychotomous
Reference EvidenceVariableHandling ( EvidenceVariable Required )
. . . . . . valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
...... valueQuantity What exposure? 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
. . . . . outcome . valueRange Σ 0..* Range Range of values for grouping of ordinal or polychotomous variables
..... attributeEstimate 0..* see attributeEstimate An attribute of the statistic used as a model characteristic
... certainty 0..* Reference BackboneElement Certainty or quality of the evidence
.... description 0..1 string Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes
.... type 0..1 CodeableConcept Aspect of certainty being rated
EvidenceCertaintyType ( EvidenceVariable Extensible )
. . . . rating What outcome? 0..1 CodeableConcept Assessment or judgement of the aspect
EvidenceCertaintyRating ( Extensible )
.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* see certainty A domain or subdomain of certainty

doco Documentation for this format

UML Diagram ( Legend )

Evidence ( DomainResource ) An absolute URI that is used to identify this evidence when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this evidence summary is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the evidence summary is stored on different servers url : uri [0..1] A formal identifier that is used to identify this evidence summary when it is represented in other formats, or referenced in a specification, model, design or an instance identifier : Identifier [0..*] The identifier that is used to identify this version of the evidence summary when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the evidence summary author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence. To provide a version consistent with the Decision Support Service specification, use the format Major.Minor.Revision (e.g. 1.0.0). For more information on versioning knowledge assets, refer to the Decision Support Service specification. Note that a version is required for non-experimental active artifacts sequence version : string [0..1] A natural language name identifying the evidence. This name should be usable as an identifier for the module by machine processing applications such as code generation name : string [0..1] A short, descriptive, user-friendly title for the evidence summary title : string [0..1] The short title provides an alternate title Citation Resource or display of suggested citation for use in informal descriptive contexts where the full, formal title is not necessary this evidence shortTitle citeAs[x] : string Element [0..1] An explanatory or alternate title for the Evidence giving additional information about its content subtitle « Reference : string ( Citation [0..1] )| markdown » The status of this evidence. summary. Enables tracking the life-cycle of the content (this element modifies the meaning of other elements) status : code [1..1] « The lifecycle status of an artifact. null (Strength=Required) PublicationStatus ! » The date (and optionally time) when the evidence summary was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the evidence summary changes date : dateTime [0..1] The name of the organization or individual that published the evidence publisher : string [0..1] Contact details to assist a user in finding and communicating with the publisher contact : ContactDetail [0..*] A free text natural language description of the evidence from a consumer's perspective description : markdown [0..1] A human-readable string to clarify or explain concepts about the resource note : Annotation [0..*] The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate evidence instances useContext : UsageContext [0..*] A legal or geographic region in which the evidence is intended to be used jurisdiction : CodeableConcept [0..*] « Countries and regions within which this artifact is targeted for use. (Strength=Extensible) Jurisdiction ValueSet + » A copyright statement relating to the evidence and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the evidence copyright : markdown [0..1] The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage approvalDate : date [0..1] The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date lastReviewDate : date [0..1] The period during which name of the evidence content was organization or is planned to be in active use individual that published the evidence effectivePeriod publisher : Period string [0..1] Descriptive topics related Contact details to the content of the Evidence. Topics provide assist a high-level categorization grouping types of Evidences that can be useful for filtering user in finding and searching communicating with the publisher topic contact : CodeableConcept ContactDetail [0..*] « High-level categorization of the definition, used for searching, sorting, and filtering. (Strength=Example) DefinitionTopic ?? » An individiual individiual, organization, or organization device primarily involved in the creation and maintenance of the content author : ContactDetail [0..*] An individual individiual, organization, or organization device primarily responsible for internal coherence of the content editor : ContactDetail [0..*] An individual individiual, organization, or organization device primarily responsible for review of some aspect of the content reviewer : ContactDetail [0..*] An individual individiual, organization, or organization device responsible for officially endorsing the content for use in some setting endorser : ContactDetail [0..*] Related artifacts such as additional documentation, justification, Link or bibliographic references citation to artifact associated with the summary relatedArtifact : RelatedArtifact [0..*] A reference to free text natural language description of the evidence from a EvidenceVariable resource consumer's perspective description : markdown [0..1] Declarative description of the Evidence assertion : markdown [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] The method to combine studies synthesisType : CodeableConcept [0..1] « null (Strength=Extensible) SynthesisType + » The type of study that defines produced this evidence studyType : CodeableConcept [0..1] « null (Strength=Extensible) StudyType + » VariableDefinition A text description or summary of the variable description : markdown [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] population for | subpopulation | exposure | referenceExposure | measuredVariable | confounder variableRole : CodeableConcept [1..1] « null (Strength=Extensible) EvidenceVariableRole + » Definition of the research actual variable related to the statistic(s) exposureBackground observed : Reference [1..1] [0..1] « Group | EvidenceVariable » A reference Definition of the intended variable related to a the Evidence intended : Reference [0..1] « Group | EvidenceVariable resource that defines » Indication of quality of match between intended variable to actual variable directnessMatch : CodeableConcept [0..1] « null (Strength=Extensible) EvidenceDirectness + » Statistic A description of the exposure for content value of the research statistic exposureVariant description : Reference string [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] Type of statistic, eg relative risk statisticType : CodeableConcept [0..1] « EvidenceVariable null (Strength=Extensible) StatisticType + » When the measured variable is handled categorically, the category element is used to define which category the statistic is reporting category : CodeableConcept [0..1] Statistic value quantity : Quantity [0..1] The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipants numberOfEvents : unsignedInt [0..1] The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipants numberAffected : unsignedInt [0..1] SampleSize Human-readable summary of population sample size description : string [0..1] Footnote or explanatory note about the sample size note : Annotation [0..*] Number of participants in the population numberOfStudies : unsignedInt [0..1] A reference human-readable string to a EvidenceVariable resomece that defines clarify or explain concepts about the outcome sample size numberOfParticipants : unsignedInt [0..1] Number of participants with known results for measured variables knownDataCount : unsignedInt [0..1] AttributeEstimate Human-readable summary of the research estimate outcome description : Reference string [0..1] Footnote or explanatory note about the estimate note : Annotation [0..*] The type of attribute estimate, eg confidence interval or p value type : CodeableConcept [0..1] « null (Strength=Extensible) AttributeEstimateType + » The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure quantity : Quantity [0..1] Use 95 for a 95% confidence interval level : decimal [0..1] Lower bound of confidence interval range : Range [0..1] ModelCharacteristic Description of a component of the method to generate the statistic code : CodeableConcept [1..1] « null (Strength=Extensible) StatisticModelCode + » Further specification of the quantified value of the component of the method to generate the statistic value : Quantity ( SimpleQuantity ) [0..1] Variable Description of the variable variableDefinition : Reference [1..1] « Group | EvidenceVariable » How the variable is classified for use in adjusted analysis handling : code [0..1] « null (Strength=Required) EvidenceVariableHandling ! » Description for grouping of ordinal or polychotomous variables valueCategory : CodeableConcept [0..*] Discrete value for grouping of ordinal or polychotomous variables valueQuantity : Quantity [0..*] Range of values for grouping of ordinal or polychotomous variables valueRange : Range [0..*] Certainty Textual description of certainty description : string [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] Aspect of certainty being rated type : CodeableConcept [0..1] « null (Strength=Extensible) EvidenceCertaintyType + » Assessment or judgement of the aspect rating : CodeableConcept [0..1] « null (Strength=Extensible) EvidenceCertaintyRating + » Individual or group who did the rating rater : string [0..1] Evidence variable such as population, exposure, or outcome variableDefinition [1..*] Number of samples in the statistic sampleSize [0..1] A nested attribute estimate; which is the attribute estimate of an attribute estimate attributeEstimate [0..*] A statistical attribute of the statistic such as a measure of heterogeneity attributeEstimate [0..*] A variable adjusted for in the adjusted analysis variable [0..*] An attribute of the statistic used as a model characteristic attributeEstimate [0..*] A component of the method to generate the statistic modelCharacteristic [0..*] Values and parameters for a single statistic statistic [0..*] A domain or subdomain of certainty subcomponent [0..*] Assessment of certainty, confidence in the estimates, or quality of the evidence certainty [0..*]

XML Template 

<

<Evidence xmlns="http://hl7.org/fhir"> doco

 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <
 <</identifier>
 <
 <
 <
 <
 <
 <
 <

 <url value="[uri]"/><!-- 0..1 Canonical identifier for this evidence, represented as a globally unique URI -->
 <identifier><!-- 0..* Identifier Additional identifier for the summary --></identifier>
 <version value="[string]"/><!-- 0..1 Business version of this summary -->
 <title value="[string]"/><!-- 0..1 Name for this summary (human friendly) -->
 <citeAs[x]><!-- 0..1 Reference(Citation)|markdown Citation for this evidence --></citeAs[x]>
 <status value="[code]"/><!-- 1..1 draft | active | retired | unknown -->
 <date value="[dateTime]"/><!-- 0..1 Date last changed -->
 <useContext><!-- 0..* UsageContext The context that the content is intended to support --></useContext>
 <approvalDate value="[date]"/><!-- 0..1 When the summary was approved by publisher -->
 <lastReviewDate value="[date]"/><!-- 0..1 When the summary was last reviewed -->

 <publisher value="[string]"/><!-- 0..1 Name of the publisher (organization or individual) -->
 <contact><!-- 0..* ContactDetail Contact details for the publisher --></contact>
 <
 <</note>
 <</useContext>
 <</jurisdiction>
 <
 <
 <
 <</effectivePeriod>
 <</topic>
 <</author>
 <</editor>
 <</reviewer>
 <</endorser>
 <</relatedArtifact>
 <</exposureBackground>
 <</exposureVariant>
 <</outcome>

 <author><!-- 0..* ContactDetail Who authored the content --></author>
 <editor><!-- 0..* ContactDetail Who edited the content --></editor>
 <reviewer><!-- 0..* ContactDetail Who reviewed the content --></reviewer>
 <endorser><!-- 0..* ContactDetail Who endorsed the content --></endorser>
 <relatedArtifact><!-- 0..* RelatedArtifact Link or citation to artifact associated with the summary --></relatedArtifact>
 <description value="[markdown]"/><!-- 0..1 Description of the particular summary -->
 <assertion value="[markdown]"/><!-- 0..1 Declarative description of the Evidence -->
 <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
 <variableDefinition>  <!-- 1..* Evidence variable such as population, exposure, or outcome -->
  <description value="[markdown]"/><!-- 0..1 A text description or summary of the variable -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <variableRole><!-- 1..1 CodeableConcept population | subpopulation | exposure | referenceExposure | measuredVariable | confounder --></variableRole>
  <observed><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the actual variable related to the statistic(s) --></observed>
  <intended><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the intended variable related to the Evidence --></intended>
  <directnessMatch><!-- 0..1 CodeableConcept low | moderate | high | exact --></directnessMatch>
 </variableDefinition>
 <synthesisType><!-- 0..1 CodeableConcept The method to combine studies --></synthesisType>
 <studyType><!-- 0..1 CodeableConcept The type of study that produced this evidence --></studyType>
 <statistic>  <!-- 0..* Values and parameters for a single statistic -->
  <description value="[string]"/><!-- 0..1 Description of content -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <statisticType><!-- 0..1 CodeableConcept Type of statistic, eg relative risk --></statisticType>
  <category><!-- 0..1 CodeableConcept Associated category for categorical variable --></category>
  <quantity><!-- 0..1 Quantity Statistic value --></quantity>
  <numberOfEvents value="[unsignedInt]"/><!-- 0..1 The number of events associated with the statistic -->
  <numberAffected value="[unsignedInt]"/><!-- 0..1 The number of participants affected -->
  <sampleSize>  <!-- 0..1 Number of samples in the statistic -->
   <description value="[string]"/><!-- 0..1 Textual description of sample size for statistic -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the sample size --></note>
   <numberOfStudies value="[unsignedInt]"/><!-- 0..1 Number of contributing studies -->
   <numberOfParticipants value="[unsignedInt]"/><!-- 0..1 Cumulative number of participants -->
   <knownDataCount value="[unsignedInt]"/><!-- 0..1 Number of participants with known results for measured variables -->
  </sampleSize>
  <attributeEstimate>  <!-- 0..* An attribute of the Statistic -->
   <description value="[string]"/><!-- 0..1 Textual description of the attribute estimate -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the estimate --></note>
   <type><!-- 0..1 CodeableConcept The type of attribute estimate, eg confidence interval or p value --></type>
   <quantity><!-- 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure --></quantity>
   <level value="[decimal]"/><!-- 0..1 Level of confidence interval, eg 0.95 for 95% confidence interval -->
   <range><!-- 0..1 Range Lower and upper bound values of the attribute estimate --></range>
   <attributeEstimate><!-- 0..* Content as for Evidence.statistic.attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate --></attributeEstimate>
  </attributeEstimate>
  <modelCharacteristic>  <!-- 0..* An aspect of the statistical model -->
   <code><!-- 1..1 CodeableConcept Model specification --></code>
   <value><!-- 0..1 Quantity(SimpleQuantity) Numerical value to complete model specification --></value>
   <variable>  <!-- 0..* A variable adjusted for in the adjusted analysis -->
    <variableDefinition><!-- 1..1 Reference(EvidenceVariable|Group) Description of the variable --></variableDefinition>
    <handling value="[code]"/><!-- 0..1 continuous | dichotomous | ordinal | polychotomous -->
    <valueCategory><!-- 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables --></valueCategory>
    <valueQuantity><!-- 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables --></valueQuantity>
    <valueRange><!-- 0..* Range Range of values for grouping of ordinal or polychotomous variables --></valueRange>
   </variable>
   <attributeEstimate><!-- 0..* Content as for Evidence.statistic.attributeEstimate An attribute of the statistic used as a model characteristic --></attributeEstimate>
  </modelCharacteristic>
 </statistic>
 <certainty>  <!-- 0..* Certainty or quality of the evidence -->
  <description value="[string]"/><!-- 0..1 Textual description of certainty -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <type><!-- 0..1 CodeableConcept Aspect of certainty being rated --></type>
  <rating><!-- 0..1 CodeableConcept Assessment or judgement of the aspect --></rating>
  <rater value="[string]"/><!-- 0..1 Individual or group who did the rating -->
  <subcomponent><!-- 0..* Content as for Evidence.certainty A domain or subdomain of certainty --></subcomponent>
 </certainty>

</Evidence>

JSON Template 

{doco
  "resourceType" : "",

  "resourceType" : "Evidence",

  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "
  "
  "
  "
  "
  "
  "
  "
  "

  "url" : "<uri>", // Canonical identifier for this evidence, represented as a globally unique URI
  "identifier" : [{ Identifier }], // Additional identifier for the summary
  "version" : "<string>", // Business version of this summary
  "title" : "<string>", // Name for this summary (human friendly)
  // citeAs[x]: Citation for this evidence. One of these 2:

  "citeAsReference" : { Reference(Citation) },
  "citeAsMarkdown" : "<markdown>",
  "status" : "<code>", // R!  draft | active | retired | unknown
  "date" : "<dateTime>", // Date last changed
  "useContext" : [{ UsageContext }], // The context that the content is intended to support
  "approvalDate" : "<date>", // When the summary was approved by publisher
  "lastReviewDate" : "<date>", // When the summary was last reviewed

  "publisher" : "<string>", // Name of the publisher (organization or individual)
  "contact" : [{ ContactDetail }], // Contact details for the publisher
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "

  "author" : [{ ContactDetail }], // Who authored the content
  "editor" : [{ ContactDetail }], // Who edited the content
  "reviewer" : [{ ContactDetail }], // Who reviewed the content
  "endorser" : [{ ContactDetail }], // Who endorsed the content
  "relatedArtifact" : [{ RelatedArtifact }], // Link or citation to artifact associated with the summary
  "description" : "<markdown>", // Description of the particular summary
  "assertion" : "<markdown>", // Declarative description of the Evidence
  "note" : [{ Annotation }], // Footnotes and/or explanatory notes
  "variableDefinition" : [{ // R!  Evidence variable such as population, exposure, or outcome
    "description" : "<markdown>", // A text description or summary of the variable
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "variableRole" : { CodeableConcept }, // R!  population | subpopulation | exposure | referenceExposure | measuredVariable | confounder
    "observed" : { Reference(EvidenceVariable|Group) }, // Definition of the actual variable related to the statistic(s)
    "intended" : { Reference(EvidenceVariable|Group) }, // Definition of the intended variable related to the Evidence
    "directnessMatch" : { CodeableConcept } // low | moderate | high | exact
  }],
  "synthesisType" : { CodeableConcept }, // The method to combine studies
  "studyType" : { CodeableConcept }, // The type of study that produced this evidence
  "statistic" : [{ // Values and parameters for a single statistic
    "description" : "<string>", // Description of content
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "statisticType" : { CodeableConcept }, // Type of statistic, eg relative risk
    "category" : { CodeableConcept }, // Associated category for categorical variable
    "quantity" : { Quantity }, // Statistic value
    "numberOfEvents" : "<unsignedInt>", // The number of events associated with the statistic
    "numberAffected" : "<unsignedInt>", // The number of participants affected
    "sampleSize" : { // Number of samples in the statistic
      "description" : "<string>", // Textual description of sample size for statistic
      "note" : [{ Annotation }], // Footnote or explanatory note about the sample size
      "numberOfStudies" : "<unsignedInt>", // Number of contributing studies
      "numberOfParticipants" : "<unsignedInt>", // Cumulative number of participants
      "knownDataCount" : "<unsignedInt>" // Number of participants with known results for measured variables
    },
    "attributeEstimate" : [{ // An attribute of the Statistic
      "description" : "<string>", // Textual description of the attribute estimate
      "note" : [{ Annotation }], // Footnote or explanatory note about the estimate
      "type" : { CodeableConcept }, // The type of attribute estimate, eg confidence interval or p value
      "quantity" : { Quantity }, // The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
      "level" : <decimal>, // Level of confidence interval, eg 0.95 for 95% confidence interval
      "range" : { Range }, // Lower and upper bound values of the attribute estimate
      "attributeEstimate" : [{ Content as for Evidence.statistic.attributeEstimate }] // A nested attribute estimate; which is the attribute estimate of an attribute estimate
    }],
    "modelCharacteristic" : [{ // An aspect of the statistical model
      "code" : { CodeableConcept }, // R!  Model specification
      "value" : { Quantity(SimpleQuantity) }, // Numerical value to complete model specification
      "variable" : [{ // A variable adjusted for in the adjusted analysis
        "variableDefinition" : { Reference(EvidenceVariable|Group) }, // R!  Description of the variable
        "handling" : "<code>", // continuous | dichotomous | ordinal | polychotomous
        "valueCategory" : [{ CodeableConcept }], // Description for grouping of ordinal or polychotomous variables
        "valueQuantity" : [{ Quantity }], // Discrete value for grouping of ordinal or polychotomous variables
        "valueRange" : [{ Range }] // Range of values for grouping of ordinal or polychotomous variables
      }],
      "attributeEstimate" : [{ Content as for Evidence.statistic.attributeEstimate }] // An attribute of the statistic used as a model characteristic
    }]
  }],
  "certainty" : [{ // Certainty or quality of the evidence
    "description" : "<string>", // Textual description of certainty
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "type" : { CodeableConcept }, // Aspect of certainty being rated
    "rating" : { CodeableConcept }, // Assessment or judgement of the aspect
    "rater" : "<string>", // Individual or group who did the rating
    "subcomponent" : [{ Content as for Evidence.certainty }] // A domain or subdomain of certainty
  }]

}

Turtle Template 

@prefix fhir: <http://hl7.org/fhir/> .doco


[ a fhir:;

[ a fhir:Evidence;

  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:

  fhir:Evidence.url [ uri ]; # 0..1 Canonical identifier for this evidence, represented as a globally unique URI
  fhir:Evidence.identifier [ Identifier ], ... ; # 0..* Additional identifier for the summary
  fhir:Evidence.version [ string ]; # 0..1 Business version of this summary
  fhir:Evidence.title [ string ]; # 0..1 Name for this summary (human friendly)
  # Evidence.citeAs[x] : 0..1 Citation for this evidence. One of these 2
    fhir:Evidence.citeAsReference [ Reference(Citation) ]
    fhir:Evidence.citeAsMarkdown [ markdown ]
  fhir:Evidence.status [ code ]; # 1..1 draft | active | retired | unknown
  fhir:Evidence.date [ dateTime ]; # 0..1 Date last changed
  fhir:Evidence.useContext [ UsageContext ], ... ; # 0..* The context that the content is intended to support
  fhir:Evidence.approvalDate [ date ]; # 0..1 When the summary was approved by publisher
  fhir:Evidence.lastReviewDate [ date ]; # 0..1 When the summary was last reviewed

  fhir:Evidence.publisher [ string ]; # 0..1 Name of the publisher (organization or individual)
  fhir:Evidence.contact [ ContactDetail ], ... ; # 0..* Contact details for the publisher
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:

  fhir:Evidence.author [ ContactDetail ], ... ; # 0..* Who authored the content
  fhir:Evidence.editor [ ContactDetail ], ... ; # 0..* Who edited the content
  fhir:Evidence.reviewer [ ContactDetail ], ... ; # 0..* Who reviewed the content
  fhir:Evidence.endorser [ ContactDetail ], ... ; # 0..* Who endorsed the content
  fhir:Evidence.relatedArtifact [ RelatedArtifact ], ... ; # 0..* Link or citation to artifact associated with the summary
  fhir:Evidence.description [ markdown ]; # 0..1 Description of the particular summary
  fhir:Evidence.assertion [ markdown ]; # 0..1 Declarative description of the Evidence
  fhir:Evidence.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
  fhir:Evidence.variableDefinition [ # 1..* Evidence variable such as population, exposure, or outcome
    fhir:Evidence.variableDefinition.description [ markdown ]; # 0..1 A text description or summary of the variable
    fhir:Evidence.variableDefinition.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
    fhir:Evidence.variableDefinition.variableRole [ CodeableConcept ]; # 1..1 population | subpopulation | exposure | referenceExposure | measuredVariable | confounder
    fhir:Evidence.variableDefinition.observed [ Reference(EvidenceVariable|Group) ]; # 0..1 Definition of the actual variable related to the statistic(s)
    fhir:Evidence.variableDefinition.intended [ Reference(EvidenceVariable|Group) ]; # 0..1 Definition of the intended variable related to the Evidence
    fhir:Evidence.variableDefinition.directnessMatch [ CodeableConcept ]; # 0..1 low | moderate | high | exact
  ], ...;
  fhir:Evidence.synthesisType [ CodeableConcept ]; # 0..1 The method to combine studies
  fhir:Evidence.studyType [ CodeableConcept ]; # 0..1 The type of study that produced this evidence
  fhir:Evidence.statistic [ # 0..* Values and parameters for a single statistic
    fhir:Evidence.statistic.description [ string ]; # 0..1 Description of content
    fhir:Evidence.statistic.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
    fhir:Evidence.statistic.statisticType [ CodeableConcept ]; # 0..1 Type of statistic, eg relative risk
    fhir:Evidence.statistic.category [ CodeableConcept ]; # 0..1 Associated category for categorical variable
    fhir:Evidence.statistic.quantity [ Quantity ]; # 0..1 Statistic value
    fhir:Evidence.statistic.numberOfEvents [ unsignedInt ]; # 0..1 The number of events associated with the statistic
    fhir:Evidence.statistic.numberAffected [ unsignedInt ]; # 0..1 The number of participants affected
    fhir:Evidence.statistic.sampleSize [ # 0..1 Number of samples in the statistic
      fhir:Evidence.statistic.sampleSize.description [ string ]; # 0..1 Textual description of sample size for statistic
      fhir:Evidence.statistic.sampleSize.note [ Annotation ], ... ; # 0..* Footnote or explanatory note about the sample size
      fhir:Evidence.statistic.sampleSize.numberOfStudies [ unsignedInt ]; # 0..1 Number of contributing studies
      fhir:Evidence.statistic.sampleSize.numberOfParticipants [ unsignedInt ]; # 0..1 Cumulative number of participants
      fhir:Evidence.statistic.sampleSize.knownDataCount [ unsignedInt ]; # 0..1 Number of participants with known results for measured variables
    ];
    fhir:Evidence.statistic.attributeEstimate [ # 0..* An attribute of the Statistic
      fhir:Evidence.statistic.attributeEstimate.description [ string ]; # 0..1 Textual description of the attribute estimate
      fhir:Evidence.statistic.attributeEstimate.note [ Annotation ], ... ; # 0..* Footnote or explanatory note about the estimate
      fhir:Evidence.statistic.attributeEstimate.type [ CodeableConcept ]; # 0..1 The type of attribute estimate, eg confidence interval or p value
      fhir:Evidence.statistic.attributeEstimate.quantity [ Quantity ]; # 0..1 The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
      fhir:Evidence.statistic.attributeEstimate.level [ decimal ]; # 0..1 Level of confidence interval, eg 0.95 for 95% confidence interval
      fhir:Evidence.statistic.attributeEstimate.range [ Range ]; # 0..1 Lower and upper bound values of the attribute estimate
      fhir:Evidence.statistic.attributeEstimate.attributeEstimate [ See Evidence.statistic.attributeEstimate ], ... ; # 0..* A nested attribute estimate; which is the attribute estimate of an attribute estimate
    ], ...;
    fhir:Evidence.statistic.modelCharacteristic [ # 0..* An aspect of the statistical model
      fhir:Evidence.statistic.modelCharacteristic.code [ CodeableConcept ]; # 1..1 Model specification
      fhir:Evidence.statistic.modelCharacteristic.value [ Quantity(SimpleQuantity) ]; # 0..1 Numerical value to complete model specification
      fhir:Evidence.statistic.modelCharacteristic.variable [ # 0..* A variable adjusted for in the adjusted analysis
        fhir:Evidence.statistic.modelCharacteristic.variable.variableDefinition [ Reference(EvidenceVariable|Group) ]; # 1..1 Description of the variable
        fhir:Evidence.statistic.modelCharacteristic.variable.handling [ code ]; # 0..1 continuous | dichotomous | ordinal | polychotomous
        fhir:Evidence.statistic.modelCharacteristic.variable.valueCategory [ CodeableConcept ], ... ; # 0..* Description for grouping of ordinal or polychotomous variables
        fhir:Evidence.statistic.modelCharacteristic.variable.valueQuantity [ Quantity ], ... ; # 0..* Discrete value for grouping of ordinal or polychotomous variables
        fhir:Evidence.statistic.modelCharacteristic.variable.valueRange [ Range ], ... ; # 0..* Range of values for grouping of ordinal or polychotomous variables
      ], ...;
      fhir:Evidence.statistic.modelCharacteristic.attributeEstimate [ See Evidence.statistic.attributeEstimate ], ... ; # 0..* An attribute of the statistic used as a model characteristic
    ], ...;
  ], ...;
  fhir:Evidence.certainty [ # 0..* Certainty or quality of the evidence
    fhir:Evidence.certainty.description [ string ]; # 0..1 Textual description of certainty
    fhir:Evidence.certainty.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
    fhir:Evidence.certainty.type [ CodeableConcept ]; # 0..1 Aspect of certainty being rated
    fhir:Evidence.certainty.rating [ CodeableConcept ]; # 0..1 Assessment or judgement of the aspect
    fhir:Evidence.certainty.rater [ string ]; # 0..1 Individual or group who did the rating
    fhir:Evidence.certainty.subcomponent [ See Evidence.certainty ], ... ; # 0..* A domain or subdomain of certainty
  ], ...;

]

Changes since R3 R4

Evidence
Evidence.citeAs[x]
  • Added Element
Evidence.assertion
  • Added Element
Evidence.variableDefinition
  • Added Mandatory Element
Evidence.variableDefinition.description
  • Added Element
Evidence.variableDefinition.note
  • Added Element
Evidence.variableDefinition.variableRole
  • Added Mandatory Element
Evidence.variableDefinition.observed
  • Added Element
Evidence.variableDefinition.intended
  • Added Element
Evidence.variableDefinition.directnessMatch
  • Added Element
Evidence.synthesisType
  • Added Element
Evidence.studyType
  • Added Element
Evidence.statistic
  • Added Element
Evidence.statistic.description
  • Added Element
Evidence.statistic.note
  • Added Element
Evidence.statistic.statisticType
  • Added Element
Evidence.statistic.category
  • Added Element
Evidence.statistic.quantity
  • Added Element
Evidence.statistic.numberOfEvents
  • Added Element
Evidence.statistic.numberAffected
  • Added Element
Evidence.statistic.sampleSize
  • Added Element
Evidence.statistic.sampleSize.description
  • Added Element
Evidence.statistic.sampleSize.note
  • Added Element
Evidence.statistic.sampleSize.numberOfStudies
  • Added Element
Evidence.statistic.sampleSize.numberOfParticipants
  • Added Element
Evidence.statistic.sampleSize.knownDataCount
  • Added Element
Evidence.statistic.attributeEstimate
  • Added Element
Evidence.statistic.attributeEstimate.description
  • Added Element
Evidence.statistic.attributeEstimate.note
  • Added Element
Evidence.statistic.attributeEstimate.type
  • Added Element
Evidence.statistic.attributeEstimate.quantity
  • Added Element
Evidence.statistic.attributeEstimate.level
  • Added Element
Evidence.statistic.attributeEstimate.range
  • Added Element
Evidence.statistic.attributeEstimate.attributeEstimate
  • Added Element
Evidence.statistic.modelCharacteristic
  • Added Element
Evidence.statistic.modelCharacteristic.code
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.value
  • Added Element
Evidence.statistic.modelCharacteristic.variable
  • Added Element
Evidence.statistic.modelCharacteristic.variable.variableDefinition
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.variable.handling
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueCategory
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueQuantity
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueRange
  • Added Element
Evidence.statistic.modelCharacteristic.attributeEstimate
  • Added Element
Evidence.certainty
  • Added Element
Evidence.certainty.description
  • Added Element
Evidence.certainty.note
  • Added Element
Evidence.certainty.type
  • Added Element
Evidence.certainty.rating
  • Added Element
Evidence.certainty.rater
  • Added Element
Evidence.certainty.subcomponent
  • Added Element
Evidence.name
  • deleted
Evidence.shortTitle
  • deleted
Evidence.subtitle
  • deleted
Evidence.jurisdiction
  • deleted
Evidence.copyright
  • deleted
Evidence.effectivePeriod
  • deleted
Evidence.topic
  • deleted
Evidence.exposureBackground
  • deleted
Evidence.exposureVariant
  • deleted
Evidence.outcome
  • deleted

This resource did not exist in Release 2 See the Full Difference for further information

This analysis is available as XML or JSON .

Conversions between R3 and R4

Structure

Name Flags Card. Type Description & Constraints doco
. . Evidence I TU DomainResource A research context or question Single evidence bit
+ Warning: Name should be usable as an identifier for the module by machine processing applications such as code generation
Elements defined in Ancestors: id , meta , implicitRules , language , text , contained , extension , modifierExtension
. . . url Σ 0..1 uri Canonical identifier for this evidence, represented as a globally unique URI (globally unique)
. . . identifier Σ 0..* Identifier Additional identifier for the evidence summary
. . . version Σ 0..1 string Business version of the evidence this summary
. . title . citeAs[x] Σ 0..1 string Name Citation for this evidence (human friendly)
. shortTitle . . . citeAsReference 0..1 string Reference ( Citation ) Title for use in informal contexts
. . subtitle . . citeAsMarkdown 0..1 string markdown Subordinate title of the Evidence
. . . status ?! Σ 1..1 code draft | active | retired | unknown
PublicationStatus ( Required )
. . . date Σ 0..1 dateTime Date last changed
. . . useContext Σ 0..* UsageContext The context that the content is intended to support
... approvalDate 0..1 date When the summary was approved by publisher
. . . lastReviewDate 0..1 date When the summary was last reviewed
... publisher Σ 0..1 string Name of the publisher (organization or individual)
. . . contact Σ 0..* ContactDetail Contact details for the publisher
. . . author Σ 0..* ContactDetail Who authored the content
... editor 0..* ContactDetail Who edited the content
... reviewer 0..* ContactDetail Who reviewed the content
... endorser Σ 0..* ContactDetail Who endorsed the content
... relatedArtifact 0..* RelatedArtifact Link or citation to artifact associated with the summary
. . . description Σ 0..1 markdown Description of the particular summary
... assertion 0..1 markdown Declarative description of the Evidence
... note 0..* Annotation Footnotes and/or explanatory notes
... variableDefinition 1..* BackboneElement Evidence variable such as population, exposure, or outcome
.... description 0..1 markdown Natural language A text description or summary of the evidence variable
. . . . note 0..* Annotation Used for footnotes or Footnotes and/or explanatory notes
. . . . useContext variableRole Σ 0..* 1..1 UsageContext CodeableConcept The context that population | subpopulation | exposure | referenceExposure | measuredVariable | confounder
EvidenceVariableRole ( Extensible )
.... observed Σ 0..1 Reference ( Group | EvidenceVariable ) Definition of the content is actual variable related to the statistic(s)
.... intended 0..1 Reference ( Group | EvidenceVariable ) Definition of the intended variable related to support the Evidence
.... directnessMatch 0..1 CodeableConcept low | moderate | high | exact
EvidenceDirectness ( Extensible )
. . . synthesisType 0..1 CodeableConcept The method to combine studies
SynthesisType ( Extensible )
. . . jurisdiction studyType Σ 0..* 0..1 CodeableConcept Intended jurisdiction for The type of study that produced this evidence (if applicable)
Jurisdiction StudyType ( Extensible )
. . . statistic 0..* BackboneElement Values and parameters for a single statistic
. . . copyright . description 0..1 string Description of content
.... note 0..1 0..* markdown Annotation Use Footnotes and/or publishing restrictions explanatory notes
. . . approvalDate . statisticType 0..1 date CodeableConcept When the evidence was approved by publisher Type of statistic, eg relative risk
StatisticType ( Extensible )
. . . lastReviewDate . category 0..1 date CodeableConcept When the evidence was last reviewed Associated category for categorical variable
. . . . effectivePeriod quantity Σ 0..1 Quantity Statistic value
.... numberOfEvents 0..1 unsignedInt The number of events associated with the statistic
.... numberAffected Period 0..1 unsignedInt When The number of participants affected
.... sampleSize 0..1 BackboneElement Number of samples in the evidence is expected to be used statistic
. . . . . description 0..1 string Textual description of sample size for statistic
. . . . . topic note 0..* CodeableConcept Annotation The category of Footnote or explanatory note about the Evidence, such as Education, Treatment, Assessment, etc. sample size
DefinitionTopic
. . . . . numberOfStudies ( Example ) 0..1 unsignedInt Number of contributing studies
. . . . author . numberOfParticipants 0..1 unsignedInt Cumulative number of participants
..... knownDataCount 0..* 0..1 ContactDetail unsignedInt Who authored Number of participants with known results for measured variables
.... attributeEstimate 0..* BackboneElement An attribute of the content Statistic
. . . . . description 0..1 string Textual description of the attribute estimate
... . . editor note 0..* ContactDetail Annotation Who edited Footnote or explanatory note about the content estimate
. . . . . reviewer type 0..* 0..1 ContactDetail CodeableConcept Who reviewed the content The type of attribute estimate, eg confidence interval or p value
AttributeEstimateType ( Extensible )
. . . . . endorser quantity 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
..... level 0..1 decimal Level of confidence interval, eg 0.95 for 95% confidence interval
..... range 0..1 Range Lower and upper bound values of the attribute estimate
..... attributeEstimate 0..* see attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate
.... modelCharacteristic ContactDetail 0..* BackboneElement Who endorsed An aspect of the content statistical model
. . . . . relatedArtifact code 0..* 1..1 RelatedArtifact CodeableConcept Additional documentation, citations, etc. Model specification
StatisticModelCode ( Extensible )
. . . . exposureBackground . value Σ 0..1 SimpleQuantity Numerical value to complete model specification
..... variable 0..* BackboneElement A variable adjusted for in the adjusted analysis
...... variableDefinition 1..1 Reference ( Group | EvidenceVariable ) What population? Description of the variable
. . . . . exposureVariant . handling Σ 0..1 0..* code continuous | dichotomous | ordinal | polychotomous
Reference EvidenceVariableHandling ( EvidenceVariable Required )
. . . . . . valueCategory 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables
...... valueQuantity What exposure? 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables
. . . . . outcome . valueRange Σ 0..* Range Range of values for grouping of ordinal or polychotomous variables
..... attributeEstimate 0..* see attributeEstimate An attribute of the statistic used as a model characteristic
... certainty 0..* Reference BackboneElement Certainty or quality of the evidence
.... description 0..1 string Textual description of certainty
.... note 0..* Annotation Footnotes and/or explanatory notes
.... type 0..1 CodeableConcept Aspect of certainty being rated
EvidenceCertaintyType ( EvidenceVariable Extensible )
. . . . rating What outcome? 0..1 CodeableConcept Assessment or judgement of the aspect
EvidenceCertaintyRating ( Extensible )
.... rater 0..1 string Individual or group who did the rating
.... subcomponent 0..* see certainty A domain or subdomain of certainty

doco Documentation for this format

UML Diagram ( Legend )

Evidence ( DomainResource ) An absolute URI that is used to identify this evidence when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this evidence summary is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the evidence summary is stored on different servers url : uri [0..1] A formal identifier that is used to identify this evidence summary when it is represented in other formats, or referenced in a specification, model, design or an instance identifier : Identifier [0..*] The identifier that is used to identify this version of the evidence summary when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the evidence summary author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence. To provide a version consistent with the Decision Support Service specification, use the format Major.Minor.Revision (e.g. 1.0.0). For more information on versioning knowledge assets, refer to the Decision Support Service specification. Note that a version is required for non-experimental active artifacts sequence version : string [0..1] A natural language name identifying the evidence. This name should be usable as an identifier for the module by machine processing applications such as code generation name : string [0..1] A short, descriptive, user-friendly title for the evidence summary title : string [0..1] The short title provides an alternate title Citation Resource or display of suggested citation for use in informal descriptive contexts where the full, formal title is not necessary this evidence shortTitle citeAs[x] : string Element [0..1] An explanatory or alternate title for the Evidence giving additional information about its content subtitle « Reference : string ( Citation [0..1] )| markdown » The status of this evidence. summary. Enables tracking the life-cycle of the content (this element modifies the meaning of other elements) status : code [1..1] « The lifecycle status of an artifact. null (Strength=Required) PublicationStatus ! » The date (and optionally time) when the evidence summary was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the evidence summary changes date : dateTime [0..1] The name of the organization or individual that published the evidence publisher : string [0..1] Contact details to assist a user in finding and communicating with the publisher contact : ContactDetail [0..*] A free text natural language description of the evidence from a consumer's perspective description : markdown [0..1] A human-readable string to clarify or explain concepts about the resource note : Annotation [0..*] The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate evidence instances useContext : UsageContext [0..*] A legal or geographic region in which the evidence is intended to be used jurisdiction : CodeableConcept [0..*] « Countries and regions within which this artifact is targeted for use. (Strength=Extensible) Jurisdiction ValueSet + » A copyright statement relating to the evidence and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the evidence copyright : markdown [0..1] The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage approvalDate : date [0..1] The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date lastReviewDate : date [0..1] The period during which name of the evidence content was organization or is planned to be in active use individual that published the evidence effectivePeriod publisher : Period string [0..1] Descriptive topics related Contact details to the content of the Evidence. Topics provide assist a high-level categorization grouping types of Evidences that can be useful for filtering user in finding and searching communicating with the publisher topic contact : CodeableConcept ContactDetail [0..*] « High-level categorization of the definition, used for searching, sorting, and filtering. (Strength=Example) DefinitionTopic ?? » An individiual individiual, organization, or organization device primarily involved in the creation and maintenance of the content author : ContactDetail [0..*] An individual individiual, organization, or organization device primarily responsible for internal coherence of the content editor : ContactDetail [0..*] An individual individiual, organization, or organization device primarily responsible for review of some aspect of the content reviewer : ContactDetail [0..*] An individual individiual, organization, or organization device responsible for officially endorsing the content for use in some setting endorser : ContactDetail [0..*] Related artifacts such as additional documentation, justification, Link or bibliographic references citation to artifact associated with the summary relatedArtifact : RelatedArtifact [0..*] A reference to free text natural language description of the evidence from a EvidenceVariable resource consumer's perspective description : markdown [0..1] Declarative description of the Evidence assertion : markdown [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] The method to combine studies synthesisType : CodeableConcept [0..1] « null (Strength=Extensible) SynthesisType + » The type of study that defines produced this evidence studyType : CodeableConcept [0..1] « null (Strength=Extensible) StudyType + » VariableDefinition A text description or summary of the variable description : markdown [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] population for | subpopulation | exposure | referenceExposure | measuredVariable | confounder variableRole : CodeableConcept [1..1] « null (Strength=Extensible) EvidenceVariableRole + » Definition of the research actual variable related to the statistic(s) exposureBackground observed : Reference [1..1] [0..1] « Group | EvidenceVariable » A reference Definition of the intended variable related to a the Evidence intended : Reference [0..1] « Group | EvidenceVariable resource that defines » Indication of quality of match between intended variable to actual variable directnessMatch : CodeableConcept [0..1] « null (Strength=Extensible) EvidenceDirectness + » Statistic A description of the exposure for content value of the research statistic exposureVariant description : Reference string [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] Type of statistic, eg relative risk statisticType : CodeableConcept [0..1] « EvidenceVariable null (Strength=Extensible) StatisticType + » When the measured variable is handled categorically, the category element is used to define which category the statistic is reporting category : CodeableConcept [0..1] Statistic value quantity : Quantity [0..1] The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipants numberOfEvents : unsignedInt [0..1] The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipants numberAffected : unsignedInt [0..1] SampleSize Human-readable summary of population sample size description : string [0..1] Footnote or explanatory note about the sample size note : Annotation [0..*] Number of participants in the population numberOfStudies : unsignedInt [0..1] A reference human-readable string to a EvidenceVariable resomece that defines clarify or explain concepts about the outcome sample size numberOfParticipants : unsignedInt [0..1] Number of participants with known results for measured variables knownDataCount : unsignedInt [0..1] AttributeEstimate Human-readable summary of the research estimate outcome description : Reference string [0..1] Footnote or explanatory note about the estimate note : Annotation [0..*] The type of attribute estimate, eg confidence interval or p value type : CodeableConcept [0..1] « null (Strength=Extensible) AttributeEstimateType + » The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure quantity : Quantity [0..1] Use 95 for a 95% confidence interval level : decimal [0..1] Lower bound of confidence interval range : Range [0..1] ModelCharacteristic Description of a component of the method to generate the statistic code : CodeableConcept [1..1] « null (Strength=Extensible) StatisticModelCode + » Further specification of the quantified value of the component of the method to generate the statistic value : Quantity ( SimpleQuantity ) [0..1] Variable Description of the variable variableDefinition : Reference [1..1] « Group | EvidenceVariable » How the variable is classified for use in adjusted analysis handling : code [0..1] « null (Strength=Required) EvidenceVariableHandling ! » Description for grouping of ordinal or polychotomous variables valueCategory : CodeableConcept [0..*] Discrete value for grouping of ordinal or polychotomous variables valueQuantity : Quantity [0..*] Range of values for grouping of ordinal or polychotomous variables valueRange : Range [0..*] Certainty Textual description of certainty description : string [0..1] Footnotes and/or explanatory notes note : Annotation [0..*] Aspect of certainty being rated type : CodeableConcept [0..1] « null (Strength=Extensible) EvidenceCertaintyType + » Assessment or judgement of the aspect rating : CodeableConcept [0..1] « null (Strength=Extensible) EvidenceCertaintyRating + » Individual or group who did the rating rater : string [0..1] Evidence variable such as population, exposure, or outcome variableDefinition [1..*] Number of samples in the statistic sampleSize [0..1] A nested attribute estimate; which is the attribute estimate of an attribute estimate attributeEstimate [0..*] A statistical attribute of the statistic such as a measure of heterogeneity attributeEstimate [0..*] A variable adjusted for in the adjusted analysis variable [0..*] An attribute of the statistic used as a model characteristic attributeEstimate [0..*] A component of the method to generate the statistic modelCharacteristic [0..*] Values and parameters for a single statistic statistic [0..*] A domain or subdomain of certainty subcomponent [0..*] Assessment of certainty, confidence in the estimates, or quality of the evidence certainty [0..*]

XML Template 

<

<Evidence xmlns="http://hl7.org/fhir"> doco

 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <
 <</identifier>
 <
 <
 <
 <
 <
 <
 <

 <url value="[uri]"/><!-- 0..1 Canonical identifier for this evidence, represented as a globally unique URI -->
 <identifier><!-- 0..* Identifier Additional identifier for the summary --></identifier>
 <version value="[string]"/><!-- 0..1 Business version of this summary -->
 <title value="[string]"/><!-- 0..1 Name for this summary (human friendly) -->
 <citeAs[x]><!-- 0..1 Reference(Citation)|markdown Citation for this evidence --></citeAs[x]>
 <status value="[code]"/><!-- 1..1 draft | active | retired | unknown -->
 <date value="[dateTime]"/><!-- 0..1 Date last changed -->
 <useContext><!-- 0..* UsageContext The context that the content is intended to support --></useContext>
 <approvalDate value="[date]"/><!-- 0..1 When the summary was approved by publisher -->
 <lastReviewDate value="[date]"/><!-- 0..1 When the summary was last reviewed -->

 <publisher value="[string]"/><!-- 0..1 Name of the publisher (organization or individual) -->
 <contact><!-- 0..* ContactDetail Contact details for the publisher --></contact>
 <
 <</note>
 <</useContext>
 <</jurisdiction>
 <
 <
 <
 <</effectivePeriod>
 <</topic>
 <</author>
 <</editor>
 <</reviewer>
 <</endorser>
 <</relatedArtifact>
 <</exposureBackground>
 <</exposureVariant>
 <</outcome>

 <author><!-- 0..* ContactDetail Who authored the content --></author>
 <editor><!-- 0..* ContactDetail Who edited the content --></editor>
 <reviewer><!-- 0..* ContactDetail Who reviewed the content --></reviewer>
 <endorser><!-- 0..* ContactDetail Who endorsed the content --></endorser>
 <relatedArtifact><!-- 0..* RelatedArtifact Link or citation to artifact associated with the summary --></relatedArtifact>
 <description value="[markdown]"/><!-- 0..1 Description of the particular summary -->
 <assertion value="[markdown]"/><!-- 0..1 Declarative description of the Evidence -->
 <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
 <variableDefinition>  <!-- 1..* Evidence variable such as population, exposure, or outcome -->
  <description value="[markdown]"/><!-- 0..1 A text description or summary of the variable -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <variableRole><!-- 1..1 CodeableConcept population | subpopulation | exposure | referenceExposure | measuredVariable | confounder --></variableRole>
  <observed><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the actual variable related to the statistic(s) --></observed>
  <intended><!-- 0..1 Reference(EvidenceVariable|Group) Definition of the intended variable related to the Evidence --></intended>
  <directnessMatch><!-- 0..1 CodeableConcept low | moderate | high | exact --></directnessMatch>
 </variableDefinition>
 <synthesisType><!-- 0..1 CodeableConcept The method to combine studies --></synthesisType>
 <studyType><!-- 0..1 CodeableConcept The type of study that produced this evidence --></studyType>
 <statistic>  <!-- 0..* Values and parameters for a single statistic -->
  <description value="[string]"/><!-- 0..1 Description of content -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <statisticType><!-- 0..1 CodeableConcept Type of statistic, eg relative risk --></statisticType>
  <category><!-- 0..1 CodeableConcept Associated category for categorical variable --></category>
  <quantity><!-- 0..1 Quantity Statistic value --></quantity>
  <numberOfEvents value="[unsignedInt]"/><!-- 0..1 The number of events associated with the statistic -->
  <numberAffected value="[unsignedInt]"/><!-- 0..1 The number of participants affected -->
  <sampleSize>  <!-- 0..1 Number of samples in the statistic -->
   <description value="[string]"/><!-- 0..1 Textual description of sample size for statistic -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the sample size --></note>
   <numberOfStudies value="[unsignedInt]"/><!-- 0..1 Number of contributing studies -->
   <numberOfParticipants value="[unsignedInt]"/><!-- 0..1 Cumulative number of participants -->
   <knownDataCount value="[unsignedInt]"/><!-- 0..1 Number of participants with known results for measured variables -->
  </sampleSize>
  <attributeEstimate>  <!-- 0..* An attribute of the Statistic -->
   <description value="[string]"/><!-- 0..1 Textual description of the attribute estimate -->
   <note><!-- 0..* Annotation Footnote or explanatory note about the estimate --></note>
   <type><!-- 0..1 CodeableConcept The type of attribute estimate, eg confidence interval or p value --></type>
   <quantity><!-- 0..1 Quantity The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure --></quantity>
   <level value="[decimal]"/><!-- 0..1 Level of confidence interval, eg 0.95 for 95% confidence interval -->
   <range><!-- 0..1 Range Lower and upper bound values of the attribute estimate --></range>
   <attributeEstimate><!-- 0..* Content as for Evidence.statistic.attributeEstimate A nested attribute estimate; which is the attribute estimate of an attribute estimate --></attributeEstimate>
  </attributeEstimate>
  <modelCharacteristic>  <!-- 0..* An aspect of the statistical model -->
   <code><!-- 1..1 CodeableConcept Model specification --></code>
   <value><!-- 0..1 Quantity(SimpleQuantity) Numerical value to complete model specification --></value>
   <variable>  <!-- 0..* A variable adjusted for in the adjusted analysis -->
    <variableDefinition><!-- 1..1 Reference(EvidenceVariable|Group) Description of the variable --></variableDefinition>
    <handling value="[code]"/><!-- 0..1 continuous | dichotomous | ordinal | polychotomous -->
    <valueCategory><!-- 0..* CodeableConcept Description for grouping of ordinal or polychotomous variables --></valueCategory>
    <valueQuantity><!-- 0..* Quantity Discrete value for grouping of ordinal or polychotomous variables --></valueQuantity>
    <valueRange><!-- 0..* Range Range of values for grouping of ordinal or polychotomous variables --></valueRange>
   </variable>
   <attributeEstimate><!-- 0..* Content as for Evidence.statistic.attributeEstimate An attribute of the statistic used as a model characteristic --></attributeEstimate>
  </modelCharacteristic>
 </statistic>
 <certainty>  <!-- 0..* Certainty or quality of the evidence -->
  <description value="[string]"/><!-- 0..1 Textual description of certainty -->
  <note><!-- 0..* Annotation Footnotes and/or explanatory notes --></note>
  <type><!-- 0..1 CodeableConcept Aspect of certainty being rated --></type>
  <rating><!-- 0..1 CodeableConcept Assessment or judgement of the aspect --></rating>
  <rater value="[string]"/><!-- 0..1 Individual or group who did the rating -->
  <subcomponent><!-- 0..* Content as for Evidence.certainty A domain or subdomain of certainty --></subcomponent>
 </certainty>

</Evidence>

JSON Template 

{doco
  "resourceType" : "",

  "resourceType" : "Evidence",

  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "
  "
  "
  "
  "
  "
  "
  "
  "

  "url" : "<uri>", // Canonical identifier for this evidence, represented as a globally unique URI
  "identifier" : [{ Identifier }], // Additional identifier for the summary
  "version" : "<string>", // Business version of this summary
  "title" : "<string>", // Name for this summary (human friendly)
  // citeAs[x]: Citation for this evidence. One of these 2:

  "citeAsReference" : { Reference(Citation) },
  "citeAsMarkdown" : "<markdown>",
  "status" : "<code>", // R!  draft | active | retired | unknown
  "date" : "<dateTime>", // Date last changed
  "useContext" : [{ UsageContext }], // The context that the content is intended to support
  "approvalDate" : "<date>", // When the summary was approved by publisher
  "lastReviewDate" : "<date>", // When the summary was last reviewed

  "publisher" : "<string>", // Name of the publisher (organization or individual)
  "contact" : [{ ContactDetail }], // Contact details for the publisher
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "
  "

  "author" : [{ ContactDetail }], // Who authored the content
  "editor" : [{ ContactDetail }], // Who edited the content
  "reviewer" : [{ ContactDetail }], // Who reviewed the content
  "endorser" : [{ ContactDetail }], // Who endorsed the content
  "relatedArtifact" : [{ RelatedArtifact }], // Link or citation to artifact associated with the summary
  "description" : "<markdown>", // Description of the particular summary
  "assertion" : "<markdown>", // Declarative description of the Evidence
  "note" : [{ Annotation }], // Footnotes and/or explanatory notes
  "variableDefinition" : [{ // R!  Evidence variable such as population, exposure, or outcome
    "description" : "<markdown>", // A text description or summary of the variable
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "variableRole" : { CodeableConcept }, // R!  population | subpopulation | exposure | referenceExposure | measuredVariable | confounder
    "observed" : { Reference(EvidenceVariable|Group) }, // Definition of the actual variable related to the statistic(s)
    "intended" : { Reference(EvidenceVariable|Group) }, // Definition of the intended variable related to the Evidence
    "directnessMatch" : { CodeableConcept } // low | moderate | high | exact
  }],
  "synthesisType" : { CodeableConcept }, // The method to combine studies
  "studyType" : { CodeableConcept }, // The type of study that produced this evidence
  "statistic" : [{ // Values and parameters for a single statistic
    "description" : "<string>", // Description of content
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "statisticType" : { CodeableConcept }, // Type of statistic, eg relative risk
    "category" : { CodeableConcept }, // Associated category for categorical variable
    "quantity" : { Quantity }, // Statistic value
    "numberOfEvents" : "<unsignedInt>", // The number of events associated with the statistic
    "numberAffected" : "<unsignedInt>", // The number of participants affected
    "sampleSize" : { // Number of samples in the statistic
      "description" : "<string>", // Textual description of sample size for statistic
      "note" : [{ Annotation }], // Footnote or explanatory note about the sample size
      "numberOfStudies" : "<unsignedInt>", // Number of contributing studies
      "numberOfParticipants" : "<unsignedInt>", // Cumulative number of participants
      "knownDataCount" : "<unsignedInt>" // Number of participants with known results for measured variables
    },
    "attributeEstimate" : [{ // An attribute of the Statistic
      "description" : "<string>", // Textual description of the attribute estimate
      "note" : [{ Annotation }], // Footnote or explanatory note about the estimate
      "type" : { CodeableConcept }, // The type of attribute estimate, eg confidence interval or p value
      "quantity" : { Quantity }, // The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
      "level" : <decimal>, // Level of confidence interval, eg 0.95 for 95% confidence interval
      "range" : { Range }, // Lower and upper bound values of the attribute estimate
      "attributeEstimate" : [{ Content as for Evidence.statistic.attributeEstimate }] // A nested attribute estimate; which is the attribute estimate of an attribute estimate
    }],
    "modelCharacteristic" : [{ // An aspect of the statistical model
      "code" : { CodeableConcept }, // R!  Model specification
      "value" : { Quantity(SimpleQuantity) }, // Numerical value to complete model specification
      "variable" : [{ // A variable adjusted for in the adjusted analysis
        "variableDefinition" : { Reference(EvidenceVariable|Group) }, // R!  Description of the variable
        "handling" : "<code>", // continuous | dichotomous | ordinal | polychotomous
        "valueCategory" : [{ CodeableConcept }], // Description for grouping of ordinal or polychotomous variables
        "valueQuantity" : [{ Quantity }], // Discrete value for grouping of ordinal or polychotomous variables
        "valueRange" : [{ Range }] // Range of values for grouping of ordinal or polychotomous variables
      }],
      "attributeEstimate" : [{ Content as for Evidence.statistic.attributeEstimate }] // An attribute of the statistic used as a model characteristic
    }]
  }],
  "certainty" : [{ // Certainty or quality of the evidence
    "description" : "<string>", // Textual description of certainty
    "note" : [{ Annotation }], // Footnotes and/or explanatory notes
    "type" : { CodeableConcept }, // Aspect of certainty being rated
    "rating" : { CodeableConcept }, // Assessment or judgement of the aspect
    "rater" : "<string>", // Individual or group who did the rating
    "subcomponent" : [{ Content as for Evidence.certainty }] // A domain or subdomain of certainty
  }]

}

Turtle Template 

@prefix fhir: <http://hl7.org/fhir/> .doco


[ a fhir:;

[ a fhir:Evidence;

  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:

  fhir:Evidence.url [ uri ]; # 0..1 Canonical identifier for this evidence, represented as a globally unique URI
  fhir:Evidence.identifier [ Identifier ], ... ; # 0..* Additional identifier for the summary
  fhir:Evidence.version [ string ]; # 0..1 Business version of this summary
  fhir:Evidence.title [ string ]; # 0..1 Name for this summary (human friendly)
  # Evidence.citeAs[x] : 0..1 Citation for this evidence. One of these 2
    fhir:Evidence.citeAsReference [ Reference(Citation) ]
    fhir:Evidence.citeAsMarkdown [ markdown ]
  fhir:Evidence.status [ code ]; # 1..1 draft | active | retired | unknown
  fhir:Evidence.date [ dateTime ]; # 0..1 Date last changed
  fhir:Evidence.useContext [ UsageContext ], ... ; # 0..* The context that the content is intended to support
  fhir:Evidence.approvalDate [ date ]; # 0..1 When the summary was approved by publisher
  fhir:Evidence.lastReviewDate [ date ]; # 0..1 When the summary was last reviewed

  fhir:Evidence.publisher [ string ]; # 0..1 Name of the publisher (organization or individual)
  fhir:Evidence.contact [ ContactDetail ], ... ; # 0..* Contact details for the publisher
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:
  fhir:

  fhir:Evidence.author [ ContactDetail ], ... ; # 0..* Who authored the content
  fhir:Evidence.editor [ ContactDetail ], ... ; # 0..* Who edited the content
  fhir:Evidence.reviewer [ ContactDetail ], ... ; # 0..* Who reviewed the content
  fhir:Evidence.endorser [ ContactDetail ], ... ; # 0..* Who endorsed the content
  fhir:Evidence.relatedArtifact [ RelatedArtifact ], ... ; # 0..* Link or citation to artifact associated with the summary
  fhir:Evidence.description [ markdown ]; # 0..1 Description of the particular summary
  fhir:Evidence.assertion [ markdown ]; # 0..1 Declarative description of the Evidence
  fhir:Evidence.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
  fhir:Evidence.variableDefinition [ # 1..* Evidence variable such as population, exposure, or outcome
    fhir:Evidence.variableDefinition.description [ markdown ]; # 0..1 A text description or summary of the variable
    fhir:Evidence.variableDefinition.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
    fhir:Evidence.variableDefinition.variableRole [ CodeableConcept ]; # 1..1 population | subpopulation | exposure | referenceExposure | measuredVariable | confounder
    fhir:Evidence.variableDefinition.observed [ Reference(EvidenceVariable|Group) ]; # 0..1 Definition of the actual variable related to the statistic(s)
    fhir:Evidence.variableDefinition.intended [ Reference(EvidenceVariable|Group) ]; # 0..1 Definition of the intended variable related to the Evidence
    fhir:Evidence.variableDefinition.directnessMatch [ CodeableConcept ]; # 0..1 low | moderate | high | exact
  ], ...;
  fhir:Evidence.synthesisType [ CodeableConcept ]; # 0..1 The method to combine studies
  fhir:Evidence.studyType [ CodeableConcept ]; # 0..1 The type of study that produced this evidence
  fhir:Evidence.statistic [ # 0..* Values and parameters for a single statistic
    fhir:Evidence.statistic.description [ string ]; # 0..1 Description of content
    fhir:Evidence.statistic.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
    fhir:Evidence.statistic.statisticType [ CodeableConcept ]; # 0..1 Type of statistic, eg relative risk
    fhir:Evidence.statistic.category [ CodeableConcept ]; # 0..1 Associated category for categorical variable
    fhir:Evidence.statistic.quantity [ Quantity ]; # 0..1 Statistic value
    fhir:Evidence.statistic.numberOfEvents [ unsignedInt ]; # 0..1 The number of events associated with the statistic
    fhir:Evidence.statistic.numberAffected [ unsignedInt ]; # 0..1 The number of participants affected
    fhir:Evidence.statistic.sampleSize [ # 0..1 Number of samples in the statistic
      fhir:Evidence.statistic.sampleSize.description [ string ]; # 0..1 Textual description of sample size for statistic
      fhir:Evidence.statistic.sampleSize.note [ Annotation ], ... ; # 0..* Footnote or explanatory note about the sample size
      fhir:Evidence.statistic.sampleSize.numberOfStudies [ unsignedInt ]; # 0..1 Number of contributing studies
      fhir:Evidence.statistic.sampleSize.numberOfParticipants [ unsignedInt ]; # 0..1 Cumulative number of participants
      fhir:Evidence.statistic.sampleSize.knownDataCount [ unsignedInt ]; # 0..1 Number of participants with known results for measured variables
    ];
    fhir:Evidence.statistic.attributeEstimate [ # 0..* An attribute of the Statistic
      fhir:Evidence.statistic.attributeEstimate.description [ string ]; # 0..1 Textual description of the attribute estimate
      fhir:Evidence.statistic.attributeEstimate.note [ Annotation ], ... ; # 0..* Footnote or explanatory note about the estimate
      fhir:Evidence.statistic.attributeEstimate.type [ CodeableConcept ]; # 0..1 The type of attribute estimate, eg confidence interval or p value
      fhir:Evidence.statistic.attributeEstimate.quantity [ Quantity ]; # 0..1 The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure
      fhir:Evidence.statistic.attributeEstimate.level [ decimal ]; # 0..1 Level of confidence interval, eg 0.95 for 95% confidence interval
      fhir:Evidence.statistic.attributeEstimate.range [ Range ]; # 0..1 Lower and upper bound values of the attribute estimate
      fhir:Evidence.statistic.attributeEstimate.attributeEstimate [ See Evidence.statistic.attributeEstimate ], ... ; # 0..* A nested attribute estimate; which is the attribute estimate of an attribute estimate
    ], ...;
    fhir:Evidence.statistic.modelCharacteristic [ # 0..* An aspect of the statistical model
      fhir:Evidence.statistic.modelCharacteristic.code [ CodeableConcept ]; # 1..1 Model specification
      fhir:Evidence.statistic.modelCharacteristic.value [ Quantity(SimpleQuantity) ]; # 0..1 Numerical value to complete model specification
      fhir:Evidence.statistic.modelCharacteristic.variable [ # 0..* A variable adjusted for in the adjusted analysis
        fhir:Evidence.statistic.modelCharacteristic.variable.variableDefinition [ Reference(EvidenceVariable|Group) ]; # 1..1 Description of the variable
        fhir:Evidence.statistic.modelCharacteristic.variable.handling [ code ]; # 0..1 continuous | dichotomous | ordinal | polychotomous
        fhir:Evidence.statistic.modelCharacteristic.variable.valueCategory [ CodeableConcept ], ... ; # 0..* Description for grouping of ordinal or polychotomous variables
        fhir:Evidence.statistic.modelCharacteristic.variable.valueQuantity [ Quantity ], ... ; # 0..* Discrete value for grouping of ordinal or polychotomous variables
        fhir:Evidence.statistic.modelCharacteristic.variable.valueRange [ Range ], ... ; # 0..* Range of values for grouping of ordinal or polychotomous variables
      ], ...;
      fhir:Evidence.statistic.modelCharacteristic.attributeEstimate [ See Evidence.statistic.attributeEstimate ], ... ; # 0..* An attribute of the statistic used as a model characteristic
    ], ...;
  ], ...;
  fhir:Evidence.certainty [ # 0..* Certainty or quality of the evidence
    fhir:Evidence.certainty.description [ string ]; # 0..1 Textual description of certainty
    fhir:Evidence.certainty.note [ Annotation ], ... ; # 0..* Footnotes and/or explanatory notes
    fhir:Evidence.certainty.type [ CodeableConcept ]; # 0..1 Aspect of certainty being rated
    fhir:Evidence.certainty.rating [ CodeableConcept ]; # 0..1 Assessment or judgement of the aspect
    fhir:Evidence.certainty.rater [ string ]; # 0..1 Individual or group who did the rating
    fhir:Evidence.certainty.subcomponent [ See Evidence.certainty ], ... ; # 0..* A domain or subdomain of certainty
  ], ...;

]

Changes since Release 3 4

Evidence
Evidence.citeAs[x]
  • Added Element
Evidence.assertion
  • Added Element
Evidence.variableDefinition
  • Added Mandatory Element
Evidence.variableDefinition.description
  • Added Element
Evidence.variableDefinition.note
  • Added Element
Evidence.variableDefinition.variableRole
  • Added Mandatory Element
Evidence.variableDefinition.observed
  • Added Element
Evidence.variableDefinition.intended
  • Added Element
Evidence.variableDefinition.directnessMatch
  • Added Element
Evidence.synthesisType
  • Added Element
Evidence.studyType
  • Added Element
Evidence.statistic
  • Added Element
Evidence.statistic.description
  • Added Element
Evidence.statistic.note
  • Added Element
Evidence.statistic.statisticType
  • Added Element
Evidence.statistic.category
  • Added Element
Evidence.statistic.quantity
  • Added Element
Evidence.statistic.numberOfEvents
  • Added Element
Evidence.statistic.numberAffected
  • Added Element
Evidence.statistic.sampleSize
  • Added Element
Evidence.statistic.sampleSize.description
  • Added Element
Evidence.statistic.sampleSize.note
  • Added Element
Evidence.statistic.sampleSize.numberOfStudies
  • Added Element
Evidence.statistic.sampleSize.numberOfParticipants
  • Added Element
Evidence.statistic.sampleSize.knownDataCount
  • Added Element
Evidence.statistic.attributeEstimate
  • Added Element
Evidence.statistic.attributeEstimate.description
  • Added Element
Evidence.statistic.attributeEstimate.note
  • Added Element
Evidence.statistic.attributeEstimate.type
  • Added Element
Evidence.statistic.attributeEstimate.quantity
  • Added Element
Evidence.statistic.attributeEstimate.level
  • Added Element
Evidence.statistic.attributeEstimate.range
  • Added Element
Evidence.statistic.attributeEstimate.attributeEstimate
  • Added Element
Evidence.statistic.modelCharacteristic
  • Added Element
Evidence.statistic.modelCharacteristic.code
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.value
  • Added Element
Evidence.statistic.modelCharacteristic.variable
  • Added Element
Evidence.statistic.modelCharacteristic.variable.variableDefinition
  • Added Mandatory Element
Evidence.statistic.modelCharacteristic.variable.handling
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueCategory
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueQuantity
  • Added Element
Evidence.statistic.modelCharacteristic.variable.valueRange
  • Added Element
Evidence.statistic.modelCharacteristic.attributeEstimate
  • Added Element
Evidence.certainty
  • Added Element
Evidence.certainty.description
  • Added Element
Evidence.certainty.note
  • Added Element
Evidence.certainty.type
  • Added Element
Evidence.certainty.rating
  • Added Element
Evidence.certainty.rater
  • Added Element
Evidence.certainty.subcomponent
  • Added Element
Evidence.name
  • deleted
Evidence.shortTitle
  • deleted
Evidence.subtitle
  • deleted
Evidence.jurisdiction
  • deleted
Evidence.copyright
  • deleted
Evidence.effectivePeriod
  • deleted
Evidence.topic
  • deleted
Evidence.exposureBackground
  • deleted
Evidence.exposureVariant
  • deleted
Evidence.outcome
  • deleted

This resource did not exist in Release 2 See the Full Difference for further information

This analysis is available as XML or JSON .

Conversions between R3 and R4

 

See the Profiles & Extensions and the alternate definitions: Master Definition XML + JSON , XML Schema / Schematron + JSON Schema , ShEx (for Turtle ) + see the extensions & the dependency analysis

14.9.3.1 14.10.4.1 Terminology Bindings

Evidence.jurisdiction Evidence.topic
Path Definition Type Reference
Evidence.status The lifecycle status of an artifact. Required PublicationStatus
Evidence.variableDefinition.variableRole Countries and regions within which this artifact is targeted for use. Extensible Jurisdiction ValueSet EvidenceVariableRole
Evidence.variableDefinition.directnessMatch High-level categorization of the definition, used for searching, sorting, and filtering. Example Extensible DefinitionTopic EvidenceDirectness
Evidence.synthesisType Extensible SynthesisType
Evidence.studyType Extensible StudyType
Evidence.statistic.statisticType Extensible StatisticType
Evidence.statistic.attributeEstimate.type Extensible AttributeEstimateType
Evidence.statistic.modelCharacteristic.code Extensible StatisticModelCode
Evidence.statistic.modelCharacteristic.variable.handling Required EvidenceVariableHandling
Evidence.certainty.type Extensible EvidenceCertaintyType
Evidence.certainty.rating Extensible EvidenceCertaintyRating

14.9.3.2 14.10.4.2 Constraints

id Level Location Description Expression
evi-0 cnl-0 Warning (base) Name should be usable as an identifier for the module by machine processing applications such as code generation name.exists() implies name.matches('[A-Z]([A-Za-z0-9_]){0,254}')

14.9.4 14.10.5 Search Parameters

Search parameters for this resource. The common parameters also apply. See Searching for more information about searching in REST, messaging, and services.

Name Type Description Expression In Common
composed-of reference What resource is being referenced Evidence.relatedArtifact.where(type='composed-of').resource (Any) context token A use context assigned to the evidence (Evidence.useContext.value as CodeableConcept)
context-quantity quantity A quantity- or range-valued use context assigned to the evidence (Evidence.useContext.value as Quantity) | (Evidence.useContext.value as Range)
context-type token A type of use context assigned to the evidence Evidence.useContext.code
context-type-quantity composite A use context type and quantity- or range-based value assigned to the evidence On Evidence.useContext:
  context-type: code
  context-quantity: value.as(Quantity) | value.as(Range)
context-type-value composite A use context type and value assigned to the evidence On Evidence.useContext:
  context-type: code
  context: value.as(CodeableConcept)
date N date The evidence publication date Evidence.date
depends-on reference What resource is being referenced Evidence.relatedArtifact.where(type='depends-on').resource (Any) derived-from reference What resource is being referenced Evidence.relatedArtifact.where(type='derived-from').resource (Any) description N string The description of the evidence Evidence.description
effective date The time during which the evidence is intended to be in use Evidence.effectivePeriod identifier token External identifier for the evidence Evidence.identifier
jurisdiction token Intended jurisdiction for the evidence Evidence.jurisdiction name string Computationally friendly name of the evidence Evidence.name predecessor reference What resource is being referenced Evidence.relatedArtifact.where(type='predecessor').resource (Any) publisher N string Name of the publisher of the evidence Evidence.publisher
status N token The current status of the evidence Evidence.status
successor reference What resource is being referenced Evidence.relatedArtifact.where(type='successor').resource (Any) title N string The human-friendly name of the evidence Evidence.title
topic token Topics associated with the Evidence Evidence.topic url N uri The uri that identifies the evidence Evidence.url
version N token The business version of the evidence Evidence.version