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Example Ingredient/example (XML)

Biomedical Research and Regulation Work Group Maturity Level : N/A Standards Status : Informative Compartments : No defined compartments

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Example of an inhaler ingredient, showing multiple strength measurements (id = "example")

<?xml version="1.0" encoding="UTF-8"?>


  
  display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border:
       1px solid #8da1b4; border-radius: 5px; line-height: 60% 
  
    
      
      
    
  
  
    
      
    
  
  
    
      
      
        
        
      
      
    
        <!--    A single drug only has a single strength (amount of active ingredient).

<Ingredient xmlns="http://hl7.org/fhir">
  <id value="example"/> 
  <status value="active"/> 
  <role> 
    <coding> 
      <system value="http://ema.europa.eu/example/ingredientRole"/> 
      <code value="ActiveBase"/> 
    </coding> 
  </role> 
  <manufacturer> 
    <manufacturer> 
      <reference value="Organization/example"/> 
    </manufacturer> 
  </manufacturer> 
  <substance> 
    <code> 
      <concept> 
        <coding> 
          <system value="http://ema.europa.eu/example/substance"/> 
          <code value="Wizzohaler"/> 
        </coding> 
      </concept> 
    </code> 
    <!--   A single drug only has a single strength (amount of active ingredient).
         However it can be measured in different ways, giving rise to different values
     of what is basically the same underlying strength.
         In these cases the "strength" attribute can repeat.

     of what is basically the same underlying strength.
         In these cases the "strength" attribute can repeat.

         This is common with inhalers, where the strength is the amount of ingredient
     found in a spray or puff, but which differs at

     found in a spray or puff, but which differs at

         different distances from the nozzle. The effective strength is therefore
     different when the inhaler is used with a spacer device, 

     different when the inhaler is used with a spacer device, 

         which changes the distance. Different countries may also chose to measure
     at different standard distances.

     at different standard distances.

         This is a separate concept to presentation vs. concentration strength (which
     are two ways of expressing the same numeric value).

     are two ways of expressing the same numeric value).

         Concentration strength could be in the example below, in each "strength",
     but is omitted for clarity.

     but is omitted for clarity.

         All these are different from reference strength (a strength in terms of
     a different substance). 
       -->
    
      
        
          
          
           
          
        
        
          
          
           
          
        
      
      
    
        <!--    show a different strength value for the same ingredient, measured at a different
     distance    -->
    
      
        
          
          
           
          
        
        
          
          
           
          
        
      
      
    
  

     a different substance). 
      -->
    <strength>       <presentationRatio>         <numerator>           <value value="730"/>           <unit value="mcg"/>           <system value="http://unitsofmeasure.org"/>           <code value="ug"/>         </numerator>         <denominator>           <value value="1"/>           <unit value="delivered dose"/>           <system value="http://unitsofmeasure.org"/>           <code value="{delivered dose}"/>         </denominator>       </presentationRatio>       <measurementPoint value="2cm"/>     </strength>     <!--   show a different strength value for the same ingredient, measured at a different

     distance   -->
    <strength>       <presentationRatio>         <numerator>           <value value="460"/>           <unit value="mcg"/>           <system value="http://unitsofmeasure.org"/>           <code value="ug"/>         </numerator>         <denominator>           <value value="1"/>           <unit value="delivered dose"/>           <system value="http://unitsofmeasure.org"/>           <code value="{delivered dose}"/>         </denominator>       </presentationRatio>       <measurementPoint value="5cm"/>     </strength>   </substance> 


</

Ingredient

>



Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.