Certainty Rating of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19 (id = "example-certainty-rating")

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       1px solid #8da1b4; border-radius: 5px; line-height: 60%Evidence/18812: Critically appraised summary of all-cause mortality in meta-analysis
           of RCTs of heparin for moderately ill patients with COVID-19high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial
               effect estimates barely overlapping
    
      
    
    
    
    
      
    
  
  
  
  
    
    

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  <id value="example-certainty-rating"/> 
  <identifier> 
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      <text value="FEvIR Object Identifier"/> 
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    <system value="https://fevir.net"/> 
    <value value="27756"/> 
    <assigner> 
      <display value="Computable Publishing LLC"/> 
    </assigner> 
  </identifier> 
  <date value="2021-11-02T14:48:59.890Z"/> 
  <copyright value="https://creativecommons.org/licenses/by-nc-sa/4.0/"/> 
  <artifactReference> 
    <reference value="Evidence/example-stroke-alteplase-fatalICH"/> 
    <type value="Evidence"/> 
    <display value="Critically appraised summary of all-cause mortality in meta-analysis of RCTs of
     heparin for moderately ill patients with COVID-19
  
  
    
    
    
      
        
        
        
      
    
    
      
        
        
        
      
    
    
      
    
    
    
      
      
      
        
          
          
          
        
      
      
        
          
          
          
        
      
      
        
      
    
    
      

     heparin for moderately ill patients with COVID-19"/> 
  </artifactReference>   <content>     <informationType value="rating"/>     <summary value="serious concerns with risk of bias, inconsistency, and imprecision"/>     <type>       <coding>         <system value="http://hl7.org/fhir/certainty-type"/>         <code value="Overall"/>         <display value="Overall certainty"/>       </coding>     </type>     <classifier>       <coding>         <system value="http://hl7.org/fhir/certainty-rating"/>         <code value="very-low"/>         <display value="Very low quality"/>       </coding>     </classifier>     <author>       <display value="Brian S. Alper"/>     </author>     <freeToShare value="true"/>     <component>       <informationType value="rating"/>       <summary value="risk of bias in both included trials"/>       <type>         <coding>           <system value="http://hl7.org/fhir/certainty-type"/>           <code value="RiskOfBias"/>           <display value="Risk of bias"/>         </coding>       </type>       <classifier>         <coding>           <system value="http://hl7.org/fhir/certainty-rating"/>           <code value="serious-concern"/>           <display value="serious concern"/>         </coding>       </classifier>       <author>         <display value="Brian S. Alper"/>       </author>     </component>     <component>       <informationType value="rating"/> 
      <summary value="high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial
       effect estimates barely overlapping
      
        
          
          
          
        
      
      
        
          
          
          
        
      
      
        
      
    
    
      
      
        
          
          
          
        
      
      
        
          
          
          
        
      
      
        
      
    
    
      
      
      
        
          
          
          
        
      
      
        
          
          
          
        
      
      
        
      
    
    
      
      
        
          
          
          
        
      
      
        
          
          
          
        
      
      
        
      
    
  

       effect estimates barely overlapping"/> 
      <type>         <coding>           <system value="http://hl7.org/fhir/certainty-type"/>           <code value="Inconsistency"/>           <display value="Inconsistency"/>         </coding>       </type>       <classifier>         <coding>           <system value="http://hl7.org/fhir/certainty-rating"/>           <code value="serious-concern"/>           <display value="serious concern"/>         </coding>       </classifier>       <author>         <display value="Brian S. Alper"/>       </author>     </component>     <component>       <informationType value="rating"/>       <type>         <coding>           <system value="http://hl7.org/fhir/certainty-type"/>           <code value="Indirectness"/>           <display value="Indirectness"/>         </coding>       </type>       <classifier>         <coding>           <system value="http://hl7.org/fhir/certainty-rating"/>           <code value="no-concern"/>           <display value="no serious concern"/>         </coding>       </classifier>       <author>         <display value="Brian S. Alper"/>       </author>     </component>     <component>       <informationType value="rating"/>       <summary value="95% confidence interval includes both large effects and no effects"/>       <type>         <coding>           <system value="http://hl7.org/fhir/certainty-type"/>           <code value="Imprecision"/>           <display value="Imprecision"/>         </coding>       </type>       <classifier>         <coding>           <system value="http://hl7.org/fhir/certainty-rating"/>           <code value="serious-concern"/>           <display value="serious concern"/>         </coding>       </classifier>       <author>         <display value="Brian S. Alper"/>       </author>     </component>     <component>       <informationType value="rating"/>       <type>         <coding>           <system value="http://hl7.org/fhir/certainty-type"/>           <code value="PublicationBias"/>           <display value="Publication bias"/>         </coding>       </type>       <classifier>         <coding>           <system value="http://hl7.org/fhir/certainty-rating"/>           <code value="no-concern"/>           <display value="no serious concern"/>         </coding>       </classifier>       <author>         <display value="Brian S. Alper"/>       </author>     </component>   </content> 


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