Release 5 R6 Ballot (1st Draft)

This page is part of the FHIR Specification (v5.0.0: R5 - STU v6.0.0-ballot1: Release 6 Ballot (1st Draft) (see Ballot Notes ). This is the The current published version in it's permanent home (it will always be available at this URL). is 5.0.0 . For a full list of available versions, see the Directory of published versions . Page versions: R5 R4B

Example StructureDefinition/ClinicalUseDefinition (XML)

Biomedical Research and Regulation Work Group Maturity Level : N/A Standards Status : Informative Compartments : No defined compartments

Raw XML ( canonical form + also see XML Format Specification )

Jump past Narrative

StructureDefinition for clinicalusedefinition

<?xml version="1.0" encoding="UTF-8"?>
<?xml version="1.0" encoding="UTF-8"?>

<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="ClinicalUseDefinition"/> 
  <meta> 
    

    <lastUpdated value="2023-12-18T15:12:07.602+11:00"/> 
  </meta> 
  <text> 
    <status value="generated"/> 
    <div xmlns="http://www.w3.org/1999/xhtml">
      border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align:

      <table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align:
       top;">
        border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align:

        <tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align:
         top">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="The logical name of the element">Name</a> 
          </th> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Information about the use of the element">Flags</a> 
          </th> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Minimum and Maximum # of times the the element can appear in the instance">Card.</a> 
          </th> 
          <th class="hierarchy" style="width: 100px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Reference to the type of the element">Type</a> 
          </th> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Additional information about the element">Description &amp; Constraints</a> 
            <span style="float: right">
              <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format">
                <img alt="doco" src="data:(snipped in html view)" style="background-color: inherit"/> 
              </a> 
            </span> 
          </th> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAgDsHd9/w4EQIOamFnaBgAA4M

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAgDsHd9/w4EQIOamFnaBgAA4M

          MKAACAKwNp30CqZFfFmwAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Resource"/>  
            ClinicalUseDefinition : A single issue - either an indication, contraindication,
             interaction or an undesirable effect for a medicinal product, medication, device

            <span title="ClinicalUseDefinition : A single issue - either an indication, contraindication,
             interaction or an undesirable effect for a medicinal product, medication, device

             or procedure.">ClinicalUseDefinition</span> 
            <a name="ClinicalUseDefinition"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold;

            <a href="versions.html#std-process" style="padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold;
             color: black; background-color: #fff5e6" title="Standards Status = Trial Use">TU</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="domainresource.html">DomainResource</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxA single issue - either an indication, contraindication, interaction or an undesirable

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">A single issue - either an indication, contraindication, interaction or an undesirable

             effect for a medicinal product, medication, device or procedure
            <br/>  
            + Rule: Indication, Contraindication, Interaction, UndesirableEffect and Warning

            <span style="font-style: italic" title="cud-1">+ Rule: Indication, Contraindication, Interaction, UndesirableEffect and Warning
               cannot be used in the same instance</span> 
            <br/>  
            <br/>  Elements defined in Ancestors: 
            The logical id of the resource, as used in the URL for the resource. Once assigned,

            <a href="resource.html#Resource" title="The logical id of the resource, as used in the URL for the resource. Once assigned,
             this value never changes.">id</a> , 
            The metadata about the resource. This is content that is maintained by the infrastructure.
             Changes to the content might not always be associated with version changes to the

            <a href="resource.html#Resource" title="The metadata about the resource. This is content that is maintained by the infrastructure.
             Changes to the content might not always be associated with version changes to the

             resource.">meta</a> , 
            A reference to a set of rules that were followed when the resource was constructed,
             and which must be understood when processing the content. Often, this is a reference
             to an implementation guide that defines the special rules along with other profiles

            <a href="resource.html#Resource" title="A reference to a set of rules that were followed when the resource was constructed,
             and which must be understood when processing the content. Often, this is a reference
             to an implementation guide that defines the special rules along with other profiles

             etc.">implicitRules</a> , 
            <a href="resource.html#Resource" title="The base language in which the resource is written.">language</a> , 
            A human-readable narrative that contains a summary of the resource and can be used
             to represent the content of the resource to a human. The narrative need not encode
             all the structured data, but is required to contain sufficient detail to make it
             &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions
             may define what content should be represented in the narrative to ensure clinical

            <a href="domainresource.html#DomainResource" title="A human-readable narrative that contains a summary of the resource and can be used
             to represent the content of the resource to a human. The narrative need not encode
             all the structured data, but is required to contain sufficient detail to make it
             &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions
             may define what content should be represented in the narrative to ensure clinical

             safety.">text</a> , 
            These resources do not have an independent existence apart from the resource that
             contains them - they cannot be identified independently, nor can they have their
             own independent transaction scope. This is allowed to be a Parameters resource

            <a href="domainresource.html#DomainResource" title="These resources do not have an independent existence apart from the resource that
             contains them - they cannot be identified independently, nor can they have their
             own independent transaction scope. This is allowed to be a Parameters resource

             if and only if it is referenced by a resource that provides context/meaning.">contained</a> , 
            May be used to represent additional information that is not part of the basic definition
             of the resource. To make the use of extensions safe and managable, there is a strict
             set of governance applied to the definition and use of extensions. Though any implementer
             can define an extension, there is a set of requirements that SHALL be met as part

            <a href="domainresource.html#DomainResource" title="May be used to represent additional information that is not part of the basic definition
             of the resource. To make the use of extensions safe and managable, there is a strict
             set of governance applied to the definition and use of extensions. Though any implementer
             can define an extension, there is a set of requirements that SHALL be met as part

             of the definition of the extension.">extension</a> , 
            May be used to represent additional information that is not part of the basic definition
             of the resource and that modifies the understanding of the element that contains
             it and/or the understanding of the containing element's descendants. Usually modifier
             elements provide negation or qualification. To make the use of extensions safe
             and managable, there is a strict set of governance applied to the definition and
             use of extensions. Though any implementer is allowed to define an extension, there
             is a set of requirements that SHALL be met as part of the definition of the extension.

            <a href="domainresource.html#DomainResource" title="May be used to represent additional information that is not part of the basic definition
             of the resource and that modifies the understanding of the element that contains
             it and/or the understanding of the containing element's descendants. Usually modifier
             elements provide negation or qualification. To make the use of extensions safe
             and managable, there is a strict set of governance applied to the definition and
             use of extensions. Though any implementer is allowed to define an extension, there
             is a set of requirements that SHALL be met as part of the definition of the extension.

             Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

             DomainResource (including cannot change the meaning of modifierExtension itself).">modifierExtension</a> 
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            <span title="ClinicalUseDefinition.identifier : Business identifier for this issue.">identifier</span> 
            <a name="ClinicalUseDefinition.identifier"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Identifier">Identifier</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">Business identifier for this issue
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>  
            ClinicalUseDefinition.type : indication | contraindication | interaction | undesirable-effect

            <span title="ClinicalUseDefinition.type : indication | contraindication | interaction | undesirable-effect
             | warning.">type</span> 
            <a name="ClinicalUseDefinition.type"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">1..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#code">code</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">indication | contraindication | interaction | undesirable-effect | warning
            <br/>  Binding: 
            <a href="valueset-clinical-use-definition-type.html">Clinical Use Definition Type</a>  (
            To be conformant, the concept in this element SHALL be from the specified value

            <a href="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value
             set.">Required</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.category : A categorisation of the issue, primarily for dividing
             warnings into subject heading areas such as &quot;Pregnancy and Lactation&quot;,

            <span title="ClinicalUseDefinition.category : A categorisation of the issue, primarily for dividing
             warnings into subject heading areas such as &quot;Pregnancy and Lactation&quot;,

             &quot;Overdose&quot;, &quot;Effects on Ability to Drive and Use Machines&quot;.">category</span> 
            <a name="ClinicalUseDefinition.category"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4pxA categorisation of the issue, primarily for dividing warnings into subject heading

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">A categorisation of the issue, primarily for dividing warnings into subject heading

             areas such as &quot;Pregnancy&quot;, &quot;Overdose&quot;
            <br/>  Binding: 
            <a href="valueset-clinical-use-definition-category.html">Clinical Use Definition Category</a>  (
            Instances are encouraged to draw from the specified codes for interoperability

            <a href="terminologies.html#preferred" title="Instances are encouraged to draw from the specified codes for interoperability
             purposes but are not required to do so to be considered conformant.">Preferred</a> )
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.subject : The medication, product, substance, device, procedure
             etc. for which this is an indication.

            <span title="ClinicalUseDefinition.subject : The medication, product, substance, device, procedure
             etc. for which this is an indication, contraindication, interaction, undesirable
             effect, or warning.">subject</span> 

            <a name="ClinicalUseDefinition.subject"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (
            <a href="medicinalproductdefinition.html">MedicinalProductDefinition</a>  | 
            <a href="medication.html">Medication</a>  | 
            <a href="activitydefinition.html">ActivityDefinition</a>  | 
            <a href="plandefinition.html">PlanDefinition</a>  | 
            <a href="device.html">Device</a>  | 
            <a href="devicedefinition.html">DeviceDefinition</a>  | 
            <a href="substance.html">Substance</a>  | 
            <a href="nutritionproduct.html">NutritionProduct</a>  | 
            <a href="biologicallyderivedproduct.html">BiologicallyDerivedProduct</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxThe medication, product, substance, device, procedure etc. for which this is an
             indication

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The medication, product, substance, device, procedure etc. for which this is an
             indication, contraindication, interaction, undesirable effect, or warning

            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.status : Whether this is a current issue or one that has

            <span title="ClinicalUseDefinition.status : Whether this is a current issue or one that has
             been retired etc.">status</span> 
            <a name="ClinicalUseDefinition.status"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">Whether this is a current issue or one that has been retired etc
            <br/>  Binding: 
            <a href="valueset-publication-status.html">PublicationStatus</a>  (
            Instances are encouraged to draw from the specified codes for interoperability

            <a href="terminologies.html#preferred" title="Instances are encouraged to draw from the specified codes for interoperability
             purposes but are not required to do so to be considered conformant.">Preferred</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Element"/>  
            <span title="ClinicalUseDefinition.contraindication : Specifics for when this is a contraindication.">contraindication</span> 
            <a name="ClinicalUseDefinition.contraindication"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
            padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;

            <a href="conformance-rules.html#constraints" style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;
             color: #301212; background-color: #fdf4f4;" title="This element has or is affected by some invariants">C</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Specifics for when this is a contraindication
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.contraindication.diseaseSymptomProcedure : The situation

            <span title="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure : The situation
             that is being documented as contraindicating against this item.">diseaseSymptomProcedure</span> 
            <a name="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The situation that is being documented as contraindicating against this item
            <br/>  Binding: 
            <a href="valueset-disease-symptom-procedure.html">Disease Symptom Procedure</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.contraindication.diseaseStatus : The status of the disease
             or symptom for the contraindication, for example &quot;chronic&quot; or &quot;metastatic&quot

            <span title="ClinicalUseDefinition.contraindication.diseaseStatus : The status of the disease
             or symptom for the contraindication, for example &quot;chronic&quot; or &quot;metastatic&quot

            ;.">diseaseStatus</span> 
            <a name="ClinicalUseDefinition.contraindication.diseaseStatus"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The status of the disease or symptom for the contraindication
            <br/>  Binding: 
            <a href="valueset-disease-status.html">Disease Status</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.contraindication.comorbidity : A comorbidity (concurrent

            <span title="ClinicalUseDefinition.contraindication.comorbidity : A comorbidity (concurrent
             condition) or coinfection.">comorbidity</span> 
            <a name="ClinicalUseDefinition.contraindication.comorbidity"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">A comorbidity (concurrent condition) or coinfection
            <br/>  Binding: 
            <a href="valueset-disease-symptom-procedure.html">Disease Symptom Procedure</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.contraindication.indication : The indication which this is

            <span title="ClinicalUseDefinition.contraindication.indication : The indication which this is
             a contraidication for.">indication</span> 
            <a name="ClinicalUseDefinition.contraindication.indication"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (
            <a href="clinicalusedefinition.html">ClinicalUseDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The indication which this is a contraidication for
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.contraindication.applicability : An expression that returns
             true or false, indicating whether the indication is applicable or not, after having

            <span title="ClinicalUseDefinition.contraindication.applicability : An expression that returns
             true or false, indicating whether the indication is applicable or not, after having

             applied its other elements.">applicability</span> 
            <a name="ClinicalUseDefinition.contraindication.applicability"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="metadatatypes.html#Expression">Expression</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4pxAn expression that returns true or false, indicating whether the indication is

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">An expression that returns true or false, indicating whether the indication is

             applicable or not, after having applied its other elements
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Element"/>  
            ClinicalUseDefinition.contraindication.otherTherapy : Information about the use
             of the medicinal product in relation to other therapies described as part of the

            <span title="ClinicalUseDefinition.contraindication.otherTherapy : Information about the use
             of the medicinal product in relation to other therapies described as part of the

             contraindication.">otherTherapy</span> 
            <a name="ClinicalUseDefinition.contraindication.otherTherapy"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxInformation about use of the product in relation to other therapies described as

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Information about use of the product in relation to other therapies described as

             part of the contraindication
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3NoQ0AIBR

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3NoQ0AIBR

          Dwb9r958B0KAgAcw1OfNMK0ntGGtze+n3PwAAcG4JAAAAt3RWK0BWYk6o4QAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.contraindication.otherTherapy.relationshipType : The type
             of relationship between the medicinal product indication or contraindication and

            <span title="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType : The type
             of relationship between the medicinal product indication or contraindication and

             another therapy.">relationshipType</span> 
            <a name="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">1..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4pxThe type of relationship between the product indication/contraindication and another

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The type of relationship between the product indication/contraindication and another

             therapy
            <br/>  Binding: 
            <a href="valueset-therapy-relationship-type.html">Therapy Relationship Type</a>  (
            Instances are encouraged to draw from the specified codes for interoperability

            <a href="terminologies.html#preferred" title="Instances are encouraged to draw from the specified codes for interoperability
             purposes but are not required to do so to be considered conformant.">Preferred</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.contraindication.otherTherapy.treatment : Reference to a
             specific medication (active substance, medicinal product or class of products,

            <span title="ClinicalUseDefinition.contraindication.otherTherapy.treatment : Reference to a
             specific medication (active substance, medicinal product or class of products,

             biological, food etc.) as part of an indication or contraindication.">treatment</span> 
            <a name="ClinicalUseDefinition.contraindication.otherTherapy.treatment"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">1..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="medicinalproductdefinition.html">MedicinalProductDefinition</a>  | 
            <a href="medication.html">Medication</a>  | 
            <a href="substance.html">Substance</a>  | 
            <a href="substancedefinition.html">SubstanceDefinition</a>  | 
            <a href="nutritionproduct.html">NutritionProduct</a>  | 
            <a href="biologicallyderivedproduct.html">BiologicallyDerivedProduct</a>  | 
            <a href="activitydefinition.html">ActivityDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxReference to a specific medication, substance etc. as part of an indication or

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Reference to a specific medication, substance etc. as part of an indication or

             contraindication
            <br/>  Binding: 
            <a href="valueset-therapy.html">Therapy</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Element"/>  
            <span title="ClinicalUseDefinition.indication : Specifics for when this is an indication.">indication</span> 
            <a name="ClinicalUseDefinition.indication"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
            padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;

            <a href="conformance-rules.html#constraints" style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;
             color: #301212; background-color: #fdf4f4;" title="This element has or is affected by some invariants">C</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">Specifics for when this is an indication
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.indication.diseaseSymptomProcedure : The situation that is

            <span title="ClinicalUseDefinition.indication.diseaseSymptomProcedure : The situation that is
             being documented as an indicaton for this item.">diseaseSymptomProcedure</span> 
            <a name="ClinicalUseDefinition.indication.diseaseSymptomProcedure"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The situation that is being documented as an indicaton for this item
            <br/>  Binding: 
            <a href="valueset-disease-symptom-procedure.html">Disease Symptom Procedure</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.indication.diseaseStatus : The status of the disease or symptom

            <span title="ClinicalUseDefinition.indication.diseaseStatus : The status of the disease or symptom
             for the indication, for example &quot;chronic&quot; or &quot;metastatic&quot;.">diseaseStatus</span> 
            <a name="ClinicalUseDefinition.indication.diseaseStatus"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The status of the disease or symptom for the indication
            <br/>  Binding: 
            <a href="valueset-disease-status.html">Disease Status</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.indication.comorbidity : A comorbidity (concurrent condition)

            <span title="ClinicalUseDefinition.indication.comorbidity : A comorbidity (concurrent condition)
             or coinfection as part of the indication.">comorbidity</span> 
            <a name="ClinicalUseDefinition.indication.comorbidity"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">A comorbidity or coinfection as part of the indication
            <br/>  Binding: 
            <a href="valueset-disease-symptom-procedure.html">Disease Symptom Procedure</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.indication.intendedEffect : The intended effect, aim or strategy

            <span title="ClinicalUseDefinition.indication.intendedEffect : The intended effect, aim or strategy
             to be achieved.">intendedEffect</span> 
            <a name="ClinicalUseDefinition.indication.intendedEffect"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The intended effect, aim or strategy to be achieved
            <br/>  Binding: 
            <a href="valueset-product-intended-use.html">Product Intended Use</a>  (
            Instances are encouraged to draw from the specified codes for interoperability

            <a href="terminologies.html#preferred" title="Instances are encouraged to draw from the specified codes for interoperability
             purposes but are not required to do so to be considered conformant.">Preferred</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Choice of Types"/>  
            ClinicalUseDefinition.indication.duration[x] : Timing or duration information,
             that may be associated with use with the indicated condition e.g. Adult patients
             suffering from myocardial infarction (from a few days until less than 35 days),

            <span title="ClinicalUseDefinition.indication.duration[x] : Timing or duration information,
             that may be associated with use with the indicated condition e.g. Adult patients
             suffering from myocardial infarction (from a few days until less than 35 days),

             ischaemic stroke (from 7 days until less than 6 months).">duration[x]</span> 
            <a name="ClinicalUseDefinition.indication.duration_x_"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Timing or duration information
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LsQ0AIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LsQ0AIAw

          Dwezq/WcAaqhSoDRn6ZqXXEmq42zdrWP6DwAAzHkCAADALxtMUUAsbN3VPQAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            <span title="A set of ordered Quantities defined by a low and high limit.">durationRange</span> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Range">Range</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>  
            <span title="A sequence of Unicode characters">durationString</span> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#string">string</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.indication.undesirableEffect : An unwanted side effect or
             negative outcome that may happen if you use the drug (or other subject of this

            <span title="ClinicalUseDefinition.indication.undesirableEffect : An unwanted side effect or
             negative outcome that may happen if you use the drug (or other subject of this

             resource) for this indication.">undesirableEffect</span> 
            <a name="ClinicalUseDefinition.indication.undesirableEffect"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (
            <a href="clinicalusedefinition.html">ClinicalUseDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4pxAn unwanted side effect or negative outcome of the subject of this resource when

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">An unwanted side effect or negative outcome of the subject of this resource when

             being used for this indication
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.indication.applicability : An expression that returns true
             or false, indicating whether the indication is applicable or not, after having

            <span title="ClinicalUseDefinition.indication.applicability : An expression that returns true
             or false, indicating whether the indication is applicable or not, after having

             applied its other elements.">applicability</span> 
            <a name="ClinicalUseDefinition.indication.applicability"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="metadatatypes.html#Expression">Expression</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxAn expression that returns true or false, indicating whether the indication is

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">An expression that returns true or false, indicating whether the indication is

             applicable or not, after having applied its other elements
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Element"/>  
            ClinicalUseDefinition.indication.otherTherapy : Information about the use of the

            <span title="ClinicalUseDefinition.indication.otherTherapy : Information about the use of the
             medicinal product in relation to other therapies described as part of the indication.">otherTherapy</span> 
            <a name="ClinicalUseDefinition.indication.otherTherapy"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">see 
            <a href="#ClinicalUseDefinition.contraindication.otherTherapy" title="ClinicalUseDefinition.contraindication.otherTherapy">otherTherapy</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4pxThe use of the medicinal product in relation to other therapies described as part

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The use of the medicinal product in relation to other therapies described as part

             of the indication
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Element"/>  
            <span title="ClinicalUseDefinition.interaction : Specifics for when this is an interaction.">interaction</span> 
            <a name="ClinicalUseDefinition.interaction"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
            padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;

            <a href="conformance-rules.html#constraints" style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;
             color: #301212; background-color: #fdf4f4;" title="This element has or is affected by some invariants">C</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Specifics for when this is an interaction
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Element"/>  
            ClinicalUseDefinition.interaction.interactant : The specific medication, product,

            <span title="ClinicalUseDefinition.interaction.interactant : The specific medication, product,
             food, substance etc. or laboratory test that interacts.">interactant</span> 
            <a name="ClinicalUseDefinition.interaction.interactant"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The specific medication, product, food etc. or laboratory test that interacts
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Choice of Types"/>  
            ClinicalUseDefinition.interaction.interactant.item[x] : The specific medication,

            <span title="ClinicalUseDefinition.interaction.interactant.item[x] : The specific medication,
             product, food, substance etc. or laboratory test that interacts.">item[x]</span> 
            <a name="ClinicalUseDefinition.interaction.interactant.item_x_"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">1..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The specific medication, product, food etc. or laboratory test that interacts
            <br/>  Binding: 
            <a href="valueset-interactant.html">Interactant</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAANUlEQVR4Xu3NMQoAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAANUlEQVR4Xu3NMQoAIAw

          DwP61/3+DOutUijh4gVsCIZGZUbEy9q6iu+96/Q8AAD87CgAAgFsmVtFALAxrfsEAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  itemReference
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (
            <a href="medicinalproductdefinition.html">MedicinalProductDefinition</a>  | 
            <a href="medication.html">Medication</a>  | 
            <a href="substance.html">Substance</a>  | 
            <a href="nutritionproduct.html">NutritionProduct</a>  | 
            <a href="biologicallyderivedproduct.html">BiologicallyDerivedProduct</a>  | 
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>  
            A concept that may be defined by a formal reference to a terminology or ontology

            <span title="A concept that may be defined by a formal reference to a terminology or ontology
             or may be provided by text.">itemCodeableConcept</span> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px"/> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.interaction.type : The type of the interaction e.g. drug-drug

            <span title="ClinicalUseDefinition.interaction.type : The type of the interaction e.g. drug-drug
             interaction, drug-food interaction, drug-lab test interaction.">type</span> 
            <a name="ClinicalUseDefinition.interaction.type"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The type of the interaction e.g. drug-drug interaction, drug-lab test interaction
            <br/>  Binding: 
            <a href="valueset-interaction-type.html">Interaction Type</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.interaction.effect : The effect of the interaction, for example

            <span title="ClinicalUseDefinition.interaction.effect : The effect of the interaction, for example
             &quot;reduced gastric absorption of primary medication&quot;.">effect</span> 
            <a name="ClinicalUseDefinition.interaction.effect"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxThe effect of the interaction, for example &quot;reduced gastric absorption of

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The effect of the interaction, for example &quot;reduced gastric absorption of

             primary medication&quot;
            <br/>  Binding: 
            <a href="valueset-interaction-effect.html">Interaction Effect</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.interaction.incidence : The incidence of the interaction,

            <span title="ClinicalUseDefinition.interaction.incidence : The incidence of the interaction,
             e.g. theoretical, observed.">incidence</span> 
            <a name="ClinicalUseDefinition.interaction.incidence"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The incidence of the interaction, e.g. theoretical, observed
            <br/>  Binding: 
            <a href="valueset-interaction-incidence.html">Interaction Incidence</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>  
            <span title="ClinicalUseDefinition.interaction.management : Actions for managing the interaction.">management</span> 
            <a name="ClinicalUseDefinition.interaction.management"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Actions for managing the interaction
            <br/>  Binding: 
            <a href="valueset-interaction-management.html">Interaction Management</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            <span title="ClinicalUseDefinition.population : The population group to which this applies.">population</span> 
            <a name="ClinicalUseDefinition.population"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (
            <a href="group.html">Group</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">The population group to which this applies
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            <span title="ClinicalUseDefinition.library : Logic used by the clinical use definition.">library</span> 
            <a name="ClinicalUseDefinition.library"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#canonical">canonical</a> (
            <a href="library.html">Library</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Logic used by the clinical use definition
            <br/>  
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw

          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Element"/>  
            ClinicalUseDefinition.undesirableEffect : Describe the possible undesirable effects

            <span title="ClinicalUseDefinition.undesirableEffect : Describe the possible undesirable effects
             (negative outcomes) from the use of the medicinal product as treatment.">undesirableEffect</span> 
            <a name="ClinicalUseDefinition.undesirableEffect"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
            padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;

            <a href="conformance-rules.html#constraints" style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;
             color: #301212; background-color: #fdf4f4;" title="This element has or is affected by some invariants">C</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">A possible negative outcome from the use of this treatment
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBADwftr/v8GtdbqEAthAtMspJ

          JUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>  
            ClinicalUseDefinition.undesirableEffect.symptomConditionEffect : The situation

            <span title="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect : The situation
             in which the undesirable effect may manifest.">symptomConditionEffect</span> 
            <a name="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (
            <a href="observationdefinition.html">ObservationDefinition</a> )
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The situation in which the undesirable effect may manifest
            <br/>  Binding: 
            <a href="valueset-undesirable-effect-symptom.html">Undesirable Effect Symptom</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA

          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.undesirableEffect.classification : High level classification

            <span title="ClinicalUseDefinition.undesirableEffect.classification : High level classification
             of the effect.">classification</span> 
            <a name="ClinicalUseDefinition.undesirableEffect.classification"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">High level classification of the effect
            <br/>  Binding: 
            <a href="valueset-undesirable-effect-classification.html">Undesirable Effect Classification</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAwEwfT6/ddA0GBAxO3NrLlKUj

          9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence : How often the effect

            <span title="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence : How often the effect
             is seen.">frequencyOfOccurrence</span> 
            <a name="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">How often the effect is seen
            <br/>  Binding: 
            <a href="valueset-undesirable-effect-frequency.html">Undesirabl Effect Frequency</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg

          DsHd9/w4EQIOamFnaBgAA4MMKAACAKwNp30CqZFfFmwAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Element"/>  
            ClinicalUseDefinition.warning : A critical piece of information about environmental,
             health or physical risks or hazards that serve as caution to the user. For example
             'Do not operate heavy machinery', 'May cause drowsiness', or 'Get medical advice/attention

            <span title="ClinicalUseDefinition.warning : A critical piece of information about environmental,
             health or physical risks or hazards that serve as caution to the user. For example
             'Do not operate heavy machinery', 'May cause drowsiness', or 'Get medical advice/attention

             if you feel unwell'.">warning</span> 
            <a name="ClinicalUseDefinition.warning"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
            padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;

            <a href="conformance-rules.html#constraints" style="padding-left: 3px; padding-right: 3px; border: 1px maroon solid; font-weight: bold;
             color: #301212; background-color: #fdf4f4;" title="This element has or is affected by some invariants">C</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4pxCritical environmental, health or physical risks or hazards. For example 'Do not

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">Critical environmental, health or physical risks or hazards. For example 'Do not

             operate heavy machinery', 'May cause drowsiness'
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         white">
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAwEsez6+89AqKGGJj7JzVWS+m

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;bas
          e64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAwEsez6+89AqKGGJj7JzVWS+m

          m3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>  
            ClinicalUseDefinition.warning.description : A textual definition of this warning,

            <span title="ClinicalUseDefinition.warning.description : A textual definition of this warning,
             with formatting.">description</span> 
            <a name="ClinicalUseDefinition.warning.description"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#markdown">markdown</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">A textual definition of this warning, with formatting
            <br/>  
          </td> 
        </tr> 
        border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:
         #F7F7F7">
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg

          DsHd9/w4EQIOamFnaBgAA4MMKAACAKwNp30CqZFfFmwAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/> 
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            ClinicalUseDefinition.warning.code : A coded or unformatted textual definition

            <span title="ClinicalUseDefinition.warning.code : A coded or unformatted textual definition
             of this warning.">code</span> 
            <a name="ClinicalUseDefinition.warning.code"> </a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px

          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px
           #F0F0F0 solid; padding:0px 4px 0px 4px">A coded or unformatted textual definition of this warning
            <br/>  Binding: 
            <a href="valueset-warning-type.html">Warning Type</a>  (
            Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value
             set.  The value set merely provides examples of the types of concepts intended

             to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 
        <tr> 
          <td class="hierarchy" colspan="5">
            <br/>  
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format">
              <img alt="doco" src="data:(snipped in html view)" style="background-color: inherit"/>  Documentation for this format
            </a> 
          </td> 
        </tr> 
      </table> 
    </div> 
  </text> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-category">
    <valueString value="Specialized.Medication Definition"/> 
  </extension> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="trial-use"/> 
  </extension> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="brr"/> 
  </extension> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="2"/> 
  </extension> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category">
    <valueCode value="anonymous"/> 
  </extension> 
  
    
  

  <url value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
  

  <version value="6.0.0-ballot1"/> 
  <name value="ClinicalUseDefinition"/> 
  <status value="draft"/> 
  <experimental value="false"/> 
  
  

  <date value="2023-12-18T15:12:07+11:00"/> 
  <publisher value="HL7 International / Biomedical Research and Regulation"/> 
  <contact> 
    <telecom> 
      <system value="url"/> 
      

      <value value="http://www.hl7.org/Special/committees/fiwg"/> 
    </telecom> 
  </contact> 
  <contact> 
    <telecom> 
      <system value="url"/> 
      

      <value value="http://www.hl7.org/Special/committees/rcrim"/> 
    </telecom> 
  </contact> 
  A single issue - either an indication, contraindication, interaction or an undesirable
   effect for a medicinal product, medication, device or procedure.

  <description value="A single issue - either an indication, contraindication, interaction, undesirable
   effect or warning for a medicinal product, medication, device or procedure."/> 

  <jurisdiction> 
    <coding> 
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/> 
      <code value="001"/> 
      <display value="World"/> 
    </coding> 
  </jurisdiction> 
  

  <fhirVersion value="6.0.0-ballot1"/> 
  <mapping> 
    <identity value="workflow"/> 
    <uri value="http://hl7.org/fhir/workflow"/> 
    <name value="Workflow Pattern"/> 
  </mapping> 
  <mapping> 
    <identity value="w5"/> 
    <uri value="http://hl7.org/fhir/fivews"/> 
    <name value="FiveWs Pattern Mapping"/> 
  </mapping> 
  <mapping> 
    <identity value="idmp"/> 
    <uri value="https://www.iso.org/obp/ui/#iso:std:iso:11615"/> 
    <name value="IDMP Mapping"/> 
  </mapping> 
  <mapping> 
    <identity value="rim"/> 
    <uri value="http://hl7.org/v3"/> 
    <name value="RIM Mapping"/> 
  </mapping> 
  <kind value="resource"/> 
  <abstract value="false"/> 
  <type value="ClinicalUseDefinition"/> 
  <baseDefinition value="http://hl7.org/fhir/StructureDefinition/DomainResource"/> 
  <derivation value="specialization"/> 
  <snapshot> 
    <element id="ClinicalUseDefinition">
      <path value="ClinicalUseDefinition"/> 
      A single issue - either an indication, contraindication, interaction or an undesirable

      <short value="A single issue - either an indication, contraindication, interaction or an undesirable
       effect for a medicinal product, medication, device or procedure"/> 
      A single issue - either an indication, contraindication, interaction or an undesirable

      <definition value="A single issue - either an indication, contraindication, interaction or an undesirable
       effect for a medicinal product, medication, device or procedure."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <constraint> 
        <key value="cud-1"/> 
        <severity value="error"/> 
        Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot

        <human value="Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot
         be used in the same instance"/> 
        (ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count()
         + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count()

        <expression value="(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count()
         + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count()

         + ClinicalUseDefinition.warning.count())  &lt; 2"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
      </constraint> 
      <constraint> 
        <key value="dom-2"/> 
        <severity value="error"/> 
        <human value="If the resource is contained in another resource, it SHALL NOT contain nested Resources"/> 
        <expression value="contained.contained.empty()"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/> 
      </constraint> 
      <constraint> 
        <key value="dom-3"/> 
        <severity value="error"/> 
        If the resource is contained in another resource, it SHALL be referred to from

        <human value="If the resource is contained in another resource, it SHALL be referred to from
         elsewhere in the resource or SHALL refer to the containing resource"/> 
        contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofTy
        pe(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url)))
         or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical)
         = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmat

        <expression value="contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().ofTy
        pe(canonical) | %resource.descendants().ofType(uri) | %resource.descendants().ofType(url)))
         or descendants().where(reference = '#').exists() or descendants().where(ofType(canonical)
         = '#').exists() or descendants().where(ofType(canonical) = '#').exists()).not()).trace('unmat

        ched', id).empty()"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/> 
      </constraint> 
      <constraint> 
        <key value="dom-4"/> 
        <severity value="error"/> 
        If a resource is contained in another resource, it SHALL NOT have a meta.versionId

        <human value="If a resource is contained in another resource, it SHALL NOT have a meta.versionId
         or a meta.lastUpdated"/> 
        <expression value="contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/> 
      </constraint> 
      <constraint> 
        <key value="dom-5"/> 
        <severity value="error"/> 
        <human value="If a resource is contained in another resource, it SHALL NOT have a security label"/> 
        <expression value="contained.meta.security.empty()"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/> 
      </constraint> 
      <constraint> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice">
          <valueBoolean value="true"/> 
        </extension> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation">
          When a resource has no narrative, only systems that fully understand the data can
           display the resource to a human safely. Including a human readable representation
           in the resource makes for a much more robust eco-system and cheaper handling of
           resources by intermediary systems. Some ecosystems restrict distribution of resources
           to only those systems that do fully understand the resources, and as a consequence
           implementers may believe that the narrative is superfluous. However experience

          <valueMarkdown value="When a resource has no narrative, only systems that fully understand the data can
           display the resource to a human safely. Including a human readable representation
           in the resource makes for a much more robust eco-system and cheaper handling of
           resources by intermediary systems. Some ecosystems restrict distribution of resources
           to only those systems that do fully understand the resources, and as a consequence
           implementers may believe that the narrative is superfluous. However experience

           shows that such eco-systems often open up to new participants over time."/> 
        </extension> 
        <key value="dom-6"/> 
        <severity value="warning"/> 
        <human value="A resource should have narrative for robust management"/> 
        <expression value="text.`div`.exists()"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="Entity, Role, or Act"/> 
      </mapping> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition"/> 
      </mapping> 
      <mapping> 
        <identity value="w5"/> 
        <map value="clinical.general"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication, Therapeutic Indication, Interactions, Undesirable Effects"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.id">
      <path value="ClinicalUseDefinition.id"/> 
      <short value="Logical id of this artifact"/> 
      The logical id of the resource, as used in the URL for the resource. Once assigned,

      <definition value="The logical id of the resource, as used in the URL for the resource. Once assigned,
       this value never changes."/> 
      Within the context of the FHIR RESTful interactions, the resource has an id except
       for cases like the create and conditional update. Otherwise, the use of the resouce

      <comment value="Within the context of the FHIR RESTful interactions, the resource has an id except
       for cases like the create and conditional update. Otherwise, the use of the resouce

       id depends on the given use case."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Resource.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="id"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
    </element> 
    <element id="ClinicalUseDefinition.meta">
      <path value="ClinicalUseDefinition.meta"/> 
      <short value="Metadata about the resource"/> 
      The metadata about the resource. This is content that is maintained by the infrastructure.
       Changes to the content might not always be associated with version changes to the

      <definition value="The metadata about the resource. This is content that is maintained by the infrastructure.
       Changes to the content might not always be associated with version changes to the

       resource."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Resource.meta"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Meta"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
    </element> 
    <element id="ClinicalUseDefinition.implicitRules">
      <path value="ClinicalUseDefinition.implicitRules"/> 
      <short value="A set of rules under which this content was created"/> 
      A reference to a set of rules that were followed when the resource was constructed,
       and which must be understood when processing the content. Often, this is a reference
       to an implementation guide that defines the special rules along with other profiles

      <definition value="A reference to a set of rules that were followed when the resource was constructed,
       and which must be understood when processing the content. Often, this is a reference
       to an implementation guide that defines the special rules along with other profiles

       etc."/> 
      Asserting this rule set restricts the content to be only understood by a limited
       set of trading partners. This inherently limits the usefulness of the data in the
       long term. However, the existing health eco-system is highly fractured, and not
       yet ready to define, collect, and exchange data in a generally computable sense.
       Wherever possible, implementers and/or specification writers should avoid using
       this element. Often, when used, the URL is a reference to an implementation guide
       that defines these special rules as part of its narrative along with other profiles,

      <comment value="Asserting this rule set restricts the content to be only understood by a limited
       set of trading partners. This inherently limits the usefulness of the data in the
       long term. However, the existing health eco-system is highly fractured, and not
       yet ready to define, collect, and exchange data in a generally computable sense.
       Wherever possible, implementers and/or specification writers should avoid using
       this element. Often, when used, the URL is a reference to an implementation guide
       that defines these special rules as part of its narrative along with other profiles,

       value sets, etc."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Resource.implicitRules"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="uri"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="true"/> 
      This element is labeled as a modifier because the implicit rules may provide additional

      <isModifierReason value="This element is labeled as a modifier because the implicit rules may provide additional
       knowledge about the resource that modifies its meaning or interpretation"/> 
      <isSummary value="true"/> 
    </element> 
    <element id="ClinicalUseDefinition.language">
      <path value="ClinicalUseDefinition.language"/> 
      <short value="Language of the resource content"/> 
      <definition value="The base language in which the resource is written."/> 
      Language is provided to support indexing and accessibility (typically, services
       such as text to speech use the language tag). The html language tag in the narrative
       applies  to the narrative. The language tag on the resource may be used to specify
       the language of other presentations generated from the data in the resource. Not
       all the content has to be in the base language. The Resource.language should not
       be assumed to apply to the narrative automatically. If a language is specified,
       it should it also be specified on the div element in the html (see rules in HTML5

      <comment value="Language is provided to support indexing and accessibility (typically, services
       such as text to speech use the language tag). The html language tag in the narrative
       applies  to the narrative. The language tag on the resource may be used to specify
       the language of other presentations generated from the data in the resource. Not
       all the content has to be in the base language. The Resource.language should not
       be assumed to apply to the narrative automatically. If a language is specified,
       it should it also be specified on the div element in the html (see rules in HTML5

       for information about the relationship between xml:lang and the html lang attribute)."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Resource.language"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="code"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="Language"/> 
        </extension> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding">
          <valueBoolean value="true"/> 
        </extension> 
        <strength value="required"/> 
        <description value="IETF language tag for a human language"/> 
        

        <valueSet value="http://hl7.org/fhir/ValueSet/all-languages|6.0.0-ballot1"/> 
        <additional> 
          <purpose value="starter"/> 
          <valueSet value="http://hl7.org/fhir/ValueSet/languages"/> 
        </additional> 
      </binding> 
    </element> 
    <element id="ClinicalUseDefinition.text">
      <path value="ClinicalUseDefinition.text"/> 
      <short value="Text summary of the resource, for human interpretation"/> 
      A human-readable narrative that contains a summary of the resource and can be used
       to represent the content of the resource to a human. The narrative need not encode
       all the structured data, but is required to contain sufficient detail to make it
       &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions
       may define what content should be represented in the narrative to ensure clinical

      <definition value="A human-readable narrative that contains a summary of the resource and can be used
       to represent the content of the resource to a human. The narrative need not encode
       all the structured data, but is required to contain sufficient detail to make it
       &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions
       may define what content should be represented in the narrative to ensure clinical

       safety."/> 
      Contained resources do not have a narrative. Resources that are not contained SHOULD
       have a narrative. In some cases, a resource may only have text with little or no
       additional discrete data (as long as all minOccurs=1 elements are satisfied). 
       This may be necessary for data from legacy systems where information is captured
       as a &quot;text blob&quot; or where text is additionally entered raw or narrated

      <comment value="Contained resources do not have a narrative. Resources that are not contained SHOULD
       have a narrative. In some cases, a resource may only have text with little or no
       additional discrete data (as long as all minOccurs=1 elements are satisfied). 
       This may be necessary for data from legacy systems where information is captured
       as a &quot;text blob&quot; or where text is additionally entered raw or narrated

       and encoded information is added later."/> 
      <alias value="narrative"/> 
      <alias value="html"/> 
      <alias value="xhtml"/> 
      <alias value="display"/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="DomainResource.text"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Narrative"/> 
      </type> 
      <condition value="dom-6"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="Act.text?"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contained">
      <path value="ClinicalUseDefinition.contained"/> 
      <short value="Contained, inline Resources"/> 
      These resources do not have an independent existence apart from the resource that
       contains them - they cannot be identified independently, nor can they have their
       own independent transaction scope. This is allowed to be a Parameters resource

      <definition value="These resources do not have an independent existence apart from the resource that
       contains them - they cannot be identified independently, nor can they have their
       own independent transaction scope. This is allowed to be a Parameters resource

       if and only if it is referenced by a resource that provides context/meaning."/> 
      This should never be done when the content can be identified properly, as once
       identification is lost, it is extremely difficult (and context dependent) to restore
       it again. Contained resources may have profiles and tags in their meta elements,

      <comment value="This should never be done when the content can be identified properly, as once
       identification is lost, it is extremely difficult (and context dependent) to restore
       it again. Contained resources may have profiles and tags in their meta elements,

       but SHALL NOT have security labels."/> 
      <alias value="inline resources"/> 
      <alias value="anonymous resources"/> 
      <alias value="contained resources"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="DomainResource.contained"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Resource"/> 
      </type> 
      <condition value="dom-2"/> 
      <condition value="dom-4"/> 
      <condition value="dom-3"/> 
      <condition value="dom-5"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.extension">
      <path value="ClinicalUseDefinition.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the resource. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the resource. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="DomainResource.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.modifierExtension">
      <path value="ClinicalUseDefinition.modifierExtension"/> 
      <short value="Extensions that cannot be ignored"/> 
      May be used to represent additional information that is not part of the basic definition
       of the resource and that modifies the understanding of the element that contains
       it and/or the understanding of the containing element's descendants. Usually modifier
       elements provide negation or qualification. To make the use of extensions safe
       and managable, there is a strict set of governance applied to the definition and
       use of extensions. Though any implementer is allowed to define an extension, there
       is a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the resource and that modifies the understanding of the element that contains
       it and/or the understanding of the containing element's descendants. Usually modifier
       elements provide negation or qualification. To make the use of extensions safe
       and managable, there is a strict set of governance applied to the definition and
       use of extensions. Though any implementer is allowed to define an extension, there
       is a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="DomainResource.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <mustSupport value="false"/> 
      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       resource that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.identifier">
      <path value="ClinicalUseDefinition.identifier"/> 
      <short value="Business identifier for this issue"/> 
      <definition value="Business identifier for this issue."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.identifier"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Identifier"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition.identifier"/> 
      </mapping> 
      <mapping> 
        <identity value="w5"/> 
        <map value="FiveWs.class"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.type">
      <path value="ClinicalUseDefinition.type"/> 
      <short value="indication | contraindication | interaction | undesirable-effect | warning"/> 
      <definition value="indication | contraindication | interaction | undesirable-effect | warning."/> 
      <min value="1"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.type"/> 
        <min value="1"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="code"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="ClinicalUseDefinitionType"/> 
        </extension> 
        <strength value="required"/> 
        <description value="Overall defining type of this clinical use definition."/> 
        

        <valueSet value="http://hl7.org/fhir/ValueSet/clinical-use-definition-type|6.0.0-ballot1"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        (the type of IDMP class, out of Contraindication, Therapeutic Indication, Interactions,

        <map value="(the type of IDMP class, out of Contraindication, Therapeutic Indication, Interactions,
         Undesirable Effects)"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.category">
      <path value="ClinicalUseDefinition.category"/> 
      A categorisation of the issue, primarily for dividing warnings into subject heading

      <short value="A categorisation of the issue, primarily for dividing warnings into subject heading
       areas such as &quot;Pregnancy&quot;, &quot;Overdose&quot;"/> 
      A categorisation of the issue, primarily for dividing warnings into subject heading
       areas such as &quot;Pregnancy and Lactation&quot;, &quot;Overdose&quot;, &quot;Effects

      <definition value="A categorisation of the issue, primarily for dividing warnings into subject heading
       areas such as &quot;Pregnancy and Lactation&quot;, &quot;Overdose&quot;, &quot;Effects

       on Ability to Drive and Use Machines&quot;."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.category"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="ClinicalUseDefinitionCategory"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="A categorisation for a clinical use information item."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/clinical-use-definition-category"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.subject">
      <path value="ClinicalUseDefinition.subject"/> 
      The medication, product, substance, device, procedure etc. for which this is an
       indication
      The medication, product, substance, device, procedure etc. for which this is an
       indication.

      <short value="The medication, product, substance, device, procedure etc. for which this is an
       indication, contraindication, interaction, undesirable effect, or warning"/> 
      <definition value="The medication, product, substance, device, procedure etc. for which this is an
       indication, contraindication, interaction, undesirable effect, or warning."/> 

      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.subject"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Medication"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ActivityDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/PlanDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Device"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/DeviceDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Substance"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/NutritionProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition.subject"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="(the link between the IDMP class and Medicinal Product)"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.status">
      <path value="ClinicalUseDefinition.status"/> 
      <short value="Whether this is a current issue or one that has been retired etc"/> 
      <definition value="Whether this is a current issue or one that has been retired etc."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.status"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="PublicationStatus"/> 
        </extension> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding">
          <valueBoolean value="true"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="The lifecycle status of an artifact."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/publication-status"/> 
      </binding> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition.status"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication">
      <path value="ClinicalUseDefinition.contraindication"/> 
      <short value="Specifics for when this is a contraindication"/> 
      <definition value="Specifics for when this is a contraindication."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.id">
      <path value="ClinicalUseDefinition.contraindication.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.extension">
      <path value="ClinicalUseDefinition.contraindication.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.modifierExtension">
      <path value="ClinicalUseDefinition.contraindication.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure">
      <path value="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure"/> 
      <short value="The situation that is being documented as contraindicating against this item"/> 
      <definition value="The situation that is being documented as contraindicating against this item."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        Contraindication.Contraindications as &quot;Disease / Symptom / Procedure&quot;

        <map value="Contraindication.Contraindications as &quot;Disease / Symptom / Procedure&quot;
         and Contraindication.Contraindications Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.diseaseStatus">
      <path value="ClinicalUseDefinition.contraindication.diseaseStatus"/> 
      <short value="The status of the disease or symptom for the contraindication"/> 
      The status of the disease or symptom for the contraindication, for example &quot;chronic&quot

      <definition value="The status of the disease or symptom for the contraindication, for example &quot;chronic&quot
      ; or &quot;metastatic&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.diseaseStatus"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseStatus"/> 
        </extension> 
        <strength value="example"/> 
        <description value="The status of a disease or symptom."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-status"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication.Disease Status"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.comorbidity">
      <path value="ClinicalUseDefinition.contraindication.comorbidity"/> 
      <short value="A comorbidity (concurrent condition) or coinfection"/> 
      <definition value="A comorbidity (concurrent condition) or coinfection."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.comorbidity"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication.Comorbidity"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.indication">
      <path value="ClinicalUseDefinition.contraindication.indication"/> 
      <short value="The indication which this is a contraidication for"/> 
      <definition value="The indication which this is a contraidication for."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.indication"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="(the link from Contraindication to Therapeutic Indication)"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.applicability">
      <path value="ClinicalUseDefinition.contraindication.applicability"/> 
      An expression that returns true or false, indicating whether the indication is

      <short value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements"/> 
      An expression that returns true or false, indicating whether the indication is

      <definition value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements."/> 
      The expression may be inlined or may be a reference to a named expression within

      <comment value="The expression may be inlined or may be a reference to a named expression within
       a logic library referenced by the library element."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.applicability"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Expression"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy"/> 
      Information about use of the product in relation to other therapies described as

      <short value="Information about use of the product in relation to other therapies described as
       part of the contraindication"/> 
      Information about the use of the medicinal product in relation to other therapies

      <definition value="Information about the use of the medicinal product in relation to other therapies
       described as part of the contraindication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.otherTherapy"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication.Other Therapy Specifics"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.id">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.extension">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.modifierExtension">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType"/> 
      The type of relationship between the product indication/contraindication and another

      <short value="The type of relationship between the product indication/contraindication and another
       therapy"/> 
      The type of relationship between the medicinal product indication or contraindication

      <definition value="The type of relationship between the medicinal product indication or contraindication
       and another therapy."/> 
      <min value="1"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType"/> 
        <min value="1"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="TherapyRelationshipType"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="Classification of relationship between a therapy and a contraindication or an indication."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/therapy-relationship-type"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Other Therapy Specifics.Therapy Relationship Type"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.treatment">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.treatment"/> 
      Reference to a specific medication, substance etc. as part of an indication or

      <short value="Reference to a specific medication, substance etc. as part of an indication or
       contraindication"/> 
      Reference to a specific medication (active substance, medicinal product or class

      <definition value="Reference to a specific medication (active substance, medicinal product or class
       of products, biological, food etc.) as part of an indication or contraindication."/> 
      <min value="1"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.contraindication.otherTherapy.treatment"/> 
        <min value="1"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Medication"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Substance"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/SubstanceDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/NutritionProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ActivityDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="Therapy"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A therapy."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/therapy"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Other Therapy Specifics.Medication"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication">
      <path value="ClinicalUseDefinition.indication"/> 
      <short value="Specifics for when this is an indication"/> 
      <definition value="Specifics for when this is an indication."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.id">
      <path value="ClinicalUseDefinition.indication.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.extension">
      <path value="ClinicalUseDefinition.indication.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.modifierExtension">
      <path value="ClinicalUseDefinition.indication.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.diseaseSymptomProcedure">
      <path value="ClinicalUseDefinition.indication.diseaseSymptomProcedure"/> 
      <short value="The situation that is being documented as an indicaton for this item"/> 
      <definition value="The situation that is being documented as an indicaton for this item."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.diseaseSymptomProcedure"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        Therapeutic Indication.Indication as &quot;Disease / Symptom / Procedure&quot;,

        <map value="Therapeutic Indication.Indication as &quot;Disease / Symptom / Procedure&quot;,
         and Therapeutic Indication.Indication Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.diseaseStatus">
      <path value="ClinicalUseDefinition.indication.diseaseStatus"/> 
      <short value="The status of the disease or symptom for the indication"/> 
      The status of the disease or symptom for the indication, for example &quot;chronic&quot;

      <definition value="The status of the disease or symptom for the indication, for example &quot;chronic&quot;
       or &quot;metastatic&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.diseaseStatus"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseStatus"/> 
        </extension> 
        <strength value="example"/> 
        <description value="The status of a disease or symptom."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-status"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Disease Status"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.comorbidity">
      <path value="ClinicalUseDefinition.indication.comorbidity"/> 
      <short value="A comorbidity or coinfection as part of the indication"/> 
      <definition value="A comorbidity (concurrent condition) or coinfection as part of the indication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.comorbidity"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Comorbidity"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.intendedEffect">
      <path value="ClinicalUseDefinition.indication.intendedEffect"/> 
      <short value="The intended effect, aim or strategy to be achieved"/> 
      <definition value="The intended effect, aim or strategy to be achieved."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.intendedEffect"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="ProductIntendedUse"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="The overall intended use of a product."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/product-intended-use"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Intended Effect"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.duration[x]">
      <path value="ClinicalUseDefinition.indication.duration[x]"/> 
      <short value="Timing or duration information"/> 
      Timing or duration information, that may be associated with use with the indicated
       condition e.g. Adult patients suffering from myocardial infarction (from a few
       days until less than 35 days), ischaemic stroke (from 7 days until less than 6

      <definition value="Timing or duration information, that may be associated with use with the indicated
       condition e.g. Adult patients suffering from myocardial infarction (from a few
       days until less than 35 days), ischaemic stroke (from 7 days until less than 6

       months)."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.duration[x]"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Range"/> 
      </type> 
      <type> 
        <code value="string"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Timing / Duration"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.undesirableEffect">
      <path value="ClinicalUseDefinition.indication.undesirableEffect"/> 
      An unwanted side effect or negative outcome of the subject of this resource when

      <short value="An unwanted side effect or negative outcome of the subject of this resource when
       being used for this indication"/> 
      An unwanted side effect or negative outcome that may happen if you use the drug

      <definition value="An unwanted side effect or negative outcome that may happen if you use the drug
       (or other subject of this resource) for this indication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.undesirableEffect"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Undesirable Effects"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.applicability">
      <path value="ClinicalUseDefinition.indication.applicability"/> 
      An expression that returns true or false, indicating whether the indication is

      <short value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements"/> 
      An expression that returns true or false, indicating whether the indication is

      <definition value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements."/> 
      The expression may be inlined or may be a reference to a named expression within

      <comment value="The expression may be inlined or may be a reference to a named expression within
       a logic library referenced by the library element."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.applicability"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Expression"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.otherTherapy">
      <path value="ClinicalUseDefinition.indication.otherTherapy"/> 
      The use of the medicinal product in relation to other therapies described as part

      <short value="The use of the medicinal product in relation to other therapies described as part
       of the indication"/> 
      Information about the use of the medicinal product in relation to other therapies

      <definition value="Information about the use of the medicinal product in relation to other therapies
       described as part of the indication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.indication.otherTherapy"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <contentReference value="#ClinicalUseDefinition.contraindication.otherTherapy"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Other Therapy Specifics"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction">
      <path value="ClinicalUseDefinition.interaction"/> 
      <short value="Specifics for when this is an interaction"/> 
      <definition value="Specifics for when this is an interaction."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.id">
      <path value="ClinicalUseDefinition.interaction.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.extension">
      <path value="ClinicalUseDefinition.interaction.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.modifierExtension">
      <path value="ClinicalUseDefinition.interaction.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant">
      <path value="ClinicalUseDefinition.interaction.interactant"/> 
      <short value="The specific medication, product, food etc. or laboratory test that interacts"/> 
      The specific medication, product, food, substance etc. or laboratory test that

      <definition value="The specific medication, product, food, substance etc. or laboratory test that
       interacts."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction.interactant"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactant and Interactions.Interactions Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant.id">
      <path value="ClinicalUseDefinition.interaction.interactant.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant.extension">
      <path value="ClinicalUseDefinition.interaction.interactant.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant.modifierExtension">
      <path value="ClinicalUseDefinition.interaction.interactant.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant.item[x]">
      <path value="ClinicalUseDefinition.interaction.interactant.item[x]"/> 
      <short value="The specific medication, product, food etc. or laboratory test that interacts"/> 
      The specific medication, product, food, substance etc. or laboratory test that

      <definition value="The specific medication, product, food, substance etc. or laboratory test that
       interacts."/> 
      <min value="1"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction.interactant.item[x]"/> 
        <min value="1"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Medication"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Substance"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/NutritionProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="Interactant"/> 
        </extension> 
        <strength value="example"/> 
        <description value="An interactant - a substance that may have a clinically significant effect on another."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interactant"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactant and Interactions.Interactions Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.type">
      <path value="ClinicalUseDefinition.interaction.type"/> 
      <short value="The type of the interaction e.g. drug-drug interaction, drug-lab test interaction"/> 
      The type of the interaction e.g. drug-drug interaction, drug-food interaction,

      <definition value="The type of the interaction e.g. drug-drug interaction, drug-food interaction,
       drug-lab test interaction."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction.type"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="InteractionType"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for an interaction between two substances."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-type"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactions Type"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.effect">
      <path value="ClinicalUseDefinition.interaction.effect"/> 
      The effect of the interaction, for example &quot;reduced gastric absorption of

      <short value="The effect of the interaction, for example &quot;reduced gastric absorption of
       primary medication&quot;"/> 
      The effect of the interaction, for example &quot;reduced gastric absorption of

      <definition value="The effect of the interaction, for example &quot;reduced gastric absorption of
       primary medication&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction.effect"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="InteractionEffect"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A interaction effect of clinical use of a medication or other substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-effect"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactions Effect"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.incidence">
      <path value="ClinicalUseDefinition.interaction.incidence"/> 
      <short value="The incidence of the interaction, e.g. theoretical, observed"/> 
      <definition value="The incidence of the interaction, e.g. theoretical, observed."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction.incidence"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirableEffectSymptom"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for incidence of occurence of an interaction."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-incidence"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactions Incidence"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.management">
      <path value="ClinicalUseDefinition.interaction.management"/> 
      <short value="Actions for managing the interaction"/> 
      <definition value="Actions for managing the interaction."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.interaction.management"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="InteractionManagement"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A type of management for an interaction of a medication or other substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-management"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Management Actions"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.population">
      <path value="ClinicalUseDefinition.population"/> 
      <short value="The population group to which this applies"/> 
      <definition value="The population group to which this applies."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.population"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Group"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Population Specifics"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.library">
      <path value="ClinicalUseDefinition.library"/> 
      <short value="Logic used by the clinical use definition"/> 
      <definition value="Logic used by the clinical use definition."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="ClinicalUseDefinition.library"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="canonical"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Library"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect">
      <path value="ClinicalUseDefinition.undesirableEffect"/> 
      <short value="A possible negative outcome from the use of this treatment"/> 
      Describe the possible undesirable effects (negative outcomes) from the use of the

      <definition value="Describe the possible undesirable effects (negative outcomes) from the use of the
       medicinal product as treatment."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.undesirableEffect"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.id">
      <path value="ClinicalUseDefinition.undesirableEffect.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.extension">
      <path value="ClinicalUseDefinition.undesirableEffect.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.modifierExtension">
      <path value="ClinicalUseDefinition.undesirableEffect.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect">
      <path value="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect"/> 
      <short value="The situation in which the undesirable effect may manifest"/> 
      <definition value="The situation in which the undesirable effect may manifest."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirableEffectSymptom"/> 
        </extension> 
        <strength value="example"/> 
        <description value="An undesirable effect of clinical use."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/undesirable-effect-symptom"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects.Undesirable Effect as &quot;Symptom / Condition / Effect&quot;"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.classification">
      <path value="ClinicalUseDefinition.undesirableEffect.classification"/> 
      <short value="High level classification of the effect"/> 
      <definition value="High level classification of the effect."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.undesirableEffect.classification"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirableEffectClassification"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for an undesirable effect."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/undesirable-effect-classification"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects.Symptom / Condition / Effect Classification"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence">
      <path value="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence"/> 
      <short value="How often the effect is seen"/> 
      <definition value="How often the effect is seen."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirablEffectFrequency"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for a frequency of occurence of an undesirable effect."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/undesirable-effect-frequency"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects.Frequency of Occurrence"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning">
      <path value="ClinicalUseDefinition.warning"/> 
      Critical environmental, health or physical risks or hazards. For example 'Do not

      <short value="Critical environmental, health or physical risks or hazards. For example 'Do not
       operate heavy machinery', 'May cause drowsiness'"/> 
      A critical piece of information about environmental, health or physical risks or
       hazards that serve as caution to the user. For example 'Do not operate heavy machinery',

      <definition value="A critical piece of information about environmental, health or physical risks or
       hazards that serve as caution to the user. For example 'Do not operate heavy machinery',

       'May cause drowsiness', or 'Get medical advice/attention if you feel unwell'."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.warning"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.id">
      <path value="ClinicalUseDefinition.warning.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      Unique id for the element within a resource (for internal references). This may

      <definition value="Unique id for the element within a resource (for internal references). This may
       be any string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

      <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler
       magic (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUrl value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <condition value="ele-1"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.extension">
      <path value="ClinicalUseDefinition.warning.extension"/> 
      <short value="Additional content defined by implementations"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part

       of the definition of the extension."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.modifierExtension">
      <path value="ClinicalUseDefinition.warning.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.

       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or

Modifier extensions SHALL NOT change the meaning of any elements on Resource or

       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

      <comment value="There can be no stigma associated with the use of extensions by any application,
       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification

       to retain a core level of simplicity for everyone."/> 
      Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be
       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition

       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneElement.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      
        
        
        
        
        
      

      <isModifier value="true"/> 
      Modifier extensions are expected to modify the meaning or interpretation of the

      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the
       element that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.description">
      <path value="ClinicalUseDefinition.warning.description"/> 
      <short value="A textual definition of this warning, with formatting"/> 
      <definition value="A textual definition of this warning, with formatting."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.warning.description"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="markdown"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.code">
      <path value="ClinicalUseDefinition.warning.code"/> 
      <short value="A coded or unformatted textual definition of this warning"/> 
      <definition value="A coded or unformatted textual definition of this warning."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="ClinicalUseDefinition.warning.code"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="WarningType"/> 
        </extension> 
        <strength value="example"/> 
        <description value="Classification of warning type."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/warning-type"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
  </snapshot> 
  <differential> 
    <element id="ClinicalUseDefinition">
      <path value="ClinicalUseDefinition"/> 
      A single issue - either an indication, contraindication, interaction or an undesirable

      <short value="A single issue - either an indication, contraindication, interaction or an undesirable
       effect for a medicinal product, medication, device or procedure"/> 
      A single issue - either an indication, contraindication, interaction or an undesirable

      <definition value="A single issue - either an indication, contraindication, interaction or an undesirable
       effect for a medicinal product, medication, device or procedure."/> 
      <min value="0"/> 
      <max value="*"/> 
      <constraint> 
        <key value="cud-1"/> 
        <severity value="error"/> 
        Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot

        <human value="Indication, Contraindication, Interaction, UndesirableEffect and Warning cannot
         be used in the same instance"/> 
        (ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count()
         + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count()

        <expression value="(ClinicalUseDefinition.indication.count() + ClinicalUseDefinition.contraindication.count()
         + ClinicalUseDefinition.interaction.count() + ClinicalUseDefinition.undesirableEffect.count()

         + ClinicalUseDefinition.warning.count())  &lt; 2"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
      </constraint> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition"/> 
      </mapping> 
      <mapping> 
        <identity value="w5"/> 
        <map value="clinical.general"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication, Therapeutic Indication, Interactions, Undesirable Effects"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.identifier">
      <path value="ClinicalUseDefinition.identifier"/> 
      <short value="Business identifier for this issue"/> 
      <definition value="Business identifier for this issue."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="Identifier"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition.identifier"/> 
      </mapping> 
      <mapping> 
        <identity value="w5"/> 
        <map value="FiveWs.class"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.type">
      <path value="ClinicalUseDefinition.type"/> 
      <short value="indication | contraindication | interaction | undesirable-effect | warning"/> 
      <definition value="indication | contraindication | interaction | undesirable-effect | warning."/> 
      <min value="1"/> 
      <max value="1"/> 
      <type> 
        <code value="code"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="ClinicalUseDefinitionType"/> 
        </extension> 
        <strength value="required"/> 
        <description value="Overall defining type of this clinical use definition."/> 
        

        <valueSet value="http://hl7.org/fhir/ValueSet/clinical-use-definition-type|6.0.0-ballot1"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        (the type of IDMP class, out of Contraindication, Therapeutic Indication, Interactions,

        <map value="(the type of IDMP class, out of Contraindication, Therapeutic Indication, Interactions,
         Undesirable Effects)"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.category">
      <path value="ClinicalUseDefinition.category"/> 
      A categorisation of the issue, primarily for dividing warnings into subject heading

      <short value="A categorisation of the issue, primarily for dividing warnings into subject heading
       areas such as &quot;Pregnancy&quot;, &quot;Overdose&quot;"/> 
      A categorisation of the issue, primarily for dividing warnings into subject heading
       areas such as &quot;Pregnancy and Lactation&quot;, &quot;Overdose&quot;, &quot;Effects

      <definition value="A categorisation of the issue, primarily for dividing warnings into subject heading
       areas such as &quot;Pregnancy and Lactation&quot;, &quot;Overdose&quot;, &quot;Effects

       on Ability to Drive and Use Machines&quot;."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="ClinicalUseDefinitionCategory"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="A categorisation for a clinical use information item."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/clinical-use-definition-category"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.subject">
      <path value="ClinicalUseDefinition.subject"/> 
      The medication, product, substance, device, procedure etc. for which this is an
       indication
      The medication, product, substance, device, procedure etc. for which this is an
       indication.

      <short value="The medication, product, substance, device, procedure etc. for which this is an
       indication, contraindication, interaction, undesirable effect, or warning"/> 
      <definition value="The medication, product, substance, device, procedure etc. for which this is an
       indication, contraindication, interaction, undesirable effect, or warning."/> 

      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Medication"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ActivityDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/PlanDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Device"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/DeviceDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Substance"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/NutritionProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition.subject"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="(the link between the IDMP class and Medicinal Product)"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.status">
      <path value="ClinicalUseDefinition.status"/> 
      <short value="Whether this is a current issue or one that has been retired etc"/> 
      <definition value="Whether this is a current issue or one that has been retired etc."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="PublicationStatus"/> 
        </extension> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding">
          <valueBoolean value="true"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="The lifecycle status of an artifact."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/publication-status"/> 
      </binding> 
      <mapping> 
        <identity value="workflow"/> 
        <map value="Definition.status"/> 
      </mapping> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication">
      <path value="ClinicalUseDefinition.contraindication"/> 
      <short value="Specifics for when this is a contraindication"/> 
      <definition value="Specifics for when this is a contraindication."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure">
      <path value="ClinicalUseDefinition.contraindication.diseaseSymptomProcedure"/> 
      <short value="The situation that is being documented as contraindicating against this item"/> 
      <definition value="The situation that is being documented as contraindicating against this item."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        Contraindication.Contraindications as &quot;Disease / Symptom / Procedure&quot;

        <map value="Contraindication.Contraindications as &quot;Disease / Symptom / Procedure&quot;
         and Contraindication.Contraindications Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.diseaseStatus">
      <path value="ClinicalUseDefinition.contraindication.diseaseStatus"/> 
      <short value="The status of the disease or symptom for the contraindication"/> 
      The status of the disease or symptom for the contraindication, for example &quot;chronic&quot

      <definition value="The status of the disease or symptom for the contraindication, for example &quot;chronic&quot
      ; or &quot;metastatic&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseStatus"/> 
        </extension> 
        <strength value="example"/> 
        <description value="The status of a disease or symptom."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-status"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication.Disease Status"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.comorbidity">
      <path value="ClinicalUseDefinition.contraindication.comorbidity"/> 
      <short value="A comorbidity (concurrent condition) or coinfection"/> 
      <definition value="A comorbidity (concurrent condition) or coinfection."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication.Comorbidity"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.indication">
      <path value="ClinicalUseDefinition.contraindication.indication"/> 
      <short value="The indication which this is a contraidication for"/> 
      <definition value="The indication which this is a contraidication for."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="(the link from Contraindication to Therapeutic Indication)"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.applicability">
      <path value="ClinicalUseDefinition.contraindication.applicability"/> 
      An expression that returns true or false, indicating whether the indication is

      <short value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements"/> 
      An expression that returns true or false, indicating whether the indication is

      <definition value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements."/> 
      The expression may be inlined or may be a reference to a named expression within

      <comment value="The expression may be inlined or may be a reference to a named expression within
       a logic library referenced by the library element."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Expression"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy"/> 
      Information about use of the product in relation to other therapies described as

      <short value="Information about use of the product in relation to other therapies described as
       part of the contraindication"/> 
      Information about the use of the medicinal product in relation to other therapies

      <definition value="Information about the use of the medicinal product in relation to other therapies
       described as part of the contraindication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Contraindication.Other Therapy Specifics"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.relationshipType"/> 
      The type of relationship between the product indication/contraindication and another

      <short value="The type of relationship between the product indication/contraindication and another
       therapy"/> 
      The type of relationship between the medicinal product indication or contraindication

      <definition value="The type of relationship between the medicinal product indication or contraindication
       and another therapy."/> 
      <min value="1"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="TherapyRelationshipType"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="Classification of relationship between a therapy and a contraindication or an indication."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/therapy-relationship-type"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Other Therapy Specifics.Therapy Relationship Type"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.contraindication.otherTherapy.treatment">
      <path value="ClinicalUseDefinition.contraindication.otherTherapy.treatment"/> 
      Reference to a specific medication, substance etc. as part of an indication or

      <short value="Reference to a specific medication, substance etc. as part of an indication or
       contraindication"/> 
      Reference to a specific medication (active substance, medicinal product or class

      <definition value="Reference to a specific medication (active substance, medicinal product or class
       of products, biological, food etc.) as part of an indication or contraindication."/> 
      <min value="1"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Medication"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Substance"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/SubstanceDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/NutritionProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ActivityDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="Therapy"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A therapy."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/therapy"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Other Therapy Specifics.Medication"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication">
      <path value="ClinicalUseDefinition.indication"/> 
      <short value="Specifics for when this is an indication"/> 
      <definition value="Specifics for when this is an indication."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.diseaseSymptomProcedure">
      <path value="ClinicalUseDefinition.indication.diseaseSymptomProcedure"/> 
      <short value="The situation that is being documented as an indicaton for this item"/> 
      <definition value="The situation that is being documented as an indicaton for this item."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        Therapeutic Indication.Indication as &quot;Disease / Symptom / Procedure&quot;,

        <map value="Therapeutic Indication.Indication as &quot;Disease / Symptom / Procedure&quot;,
         and Therapeutic Indication.Indication Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.diseaseStatus">
      <path value="ClinicalUseDefinition.indication.diseaseStatus"/> 
      <short value="The status of the disease or symptom for the indication"/> 
      The status of the disease or symptom for the indication, for example &quot;chronic&quot;

      <definition value="The status of the disease or symptom for the indication, for example &quot;chronic&quot;
       or &quot;metastatic&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseStatus"/> 
        </extension> 
        <strength value="example"/> 
        <description value="The status of a disease or symptom."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-status"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Disease Status"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.comorbidity">
      <path value="ClinicalUseDefinition.indication.comorbidity"/> 
      <short value="A comorbidity or coinfection as part of the indication"/> 
      <definition value="A comorbidity (concurrent condition) or coinfection as part of the indication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DiseaseSymptomProcedure"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A symptom, disease or procedure."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/disease-symptom-procedure"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Comorbidity"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.intendedEffect">
      <path value="ClinicalUseDefinition.indication.intendedEffect"/> 
      <short value="The intended effect, aim or strategy to be achieved"/> 
      <definition value="The intended effect, aim or strategy to be achieved."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="ProductIntendedUse"/> 
        </extension> 
        <strength value="preferred"/> 
        <description value="The overall intended use of a product."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/product-intended-use"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Intended Effect"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.duration[x]">
      <path value="ClinicalUseDefinition.indication.duration[x]"/> 
      <short value="Timing or duration information"/> 
      Timing or duration information, that may be associated with use with the indicated
       condition e.g. Adult patients suffering from myocardial infarction (from a few
       days until less than 35 days), ischaemic stroke (from 7 days until less than 6

      <definition value="Timing or duration information, that may be associated with use with the indicated
       condition e.g. Adult patients suffering from myocardial infarction (from a few
       days until less than 35 days), ischaemic stroke (from 7 days until less than 6

       months)."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Range"/> 
      </type> 
      <type> 
        <code value="string"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Timing / Duration"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.undesirableEffect">
      <path value="ClinicalUseDefinition.indication.undesirableEffect"/> 
      An unwanted side effect or negative outcome of the subject of this resource when

      <short value="An unwanted side effect or negative outcome of the subject of this resource when
       being used for this indication"/> 
      An unwanted side effect or negative outcome that may happen if you use the drug

      <definition value="An unwanted side effect or negative outcome that may happen if you use the drug
       (or other subject of this resource) for this indication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ClinicalUseDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Undesirable Effects"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.applicability">
      <path value="ClinicalUseDefinition.indication.applicability"/> 
      An expression that returns true or false, indicating whether the indication is

      <short value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements"/> 
      An expression that returns true or false, indicating whether the indication is

      <definition value="An expression that returns true or false, indicating whether the indication is
       applicable or not, after having applied its other elements."/> 
      The expression may be inlined or may be a reference to a named expression within

      <comment value="The expression may be inlined or may be a reference to a named expression within
       a logic library referenced by the library element."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Expression"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.indication.otherTherapy">
      <path value="ClinicalUseDefinition.indication.otherTherapy"/> 
      The use of the medicinal product in relation to other therapies described as part

      <short value="The use of the medicinal product in relation to other therapies described as part
       of the indication"/> 
      Information about the use of the medicinal product in relation to other therapies

      <definition value="Information about the use of the medicinal product in relation to other therapies
       described as part of the indication."/> 
      <min value="0"/> 
      <max value="*"/> 
      <contentReference value="#ClinicalUseDefinition.contraindication.otherTherapy"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Therapeutic Indication.Other Therapy Specifics"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction">
      <path value="ClinicalUseDefinition.interaction"/> 
      <short value="Specifics for when this is an interaction"/> 
      <definition value="Specifics for when this is an interaction."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant">
      <path value="ClinicalUseDefinition.interaction.interactant"/> 
      <short value="The specific medication, product, food etc. or laboratory test that interacts"/> 
      The specific medication, product, food, substance etc. or laboratory test that

      <definition value="The specific medication, product, food, substance etc. or laboratory test that
       interacts."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactant and Interactions.Interactions Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.interactant.item[x]">
      <path value="ClinicalUseDefinition.interaction.interactant.item[x]"/> 
      <short value="The specific medication, product, food etc. or laboratory test that interacts"/> 
      The specific medication, product, food, substance etc. or laboratory test that

      <definition value="The specific medication, product, food, substance etc. or laboratory test that
       interacts."/> 
      <min value="1"/> 
      <max value="1"/> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Medication"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Substance"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/NutritionProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/BiologicallyDerivedProduct"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="Interactant"/> 
        </extension> 
        <strength value="example"/> 
        <description value="An interactant - a substance that may have a clinically significant effect on another."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interactant"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactant and Interactions.Interactions Text"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.type">
      <path value="ClinicalUseDefinition.interaction.type"/> 
      <short value="The type of the interaction e.g. drug-drug interaction, drug-lab test interaction"/> 
      The type of the interaction e.g. drug-drug interaction, drug-food interaction,

      <definition value="The type of the interaction e.g. drug-drug interaction, drug-food interaction,
       drug-lab test interaction."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="InteractionType"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for an interaction between two substances."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-type"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactions Type"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.effect">
      <path value="ClinicalUseDefinition.interaction.effect"/> 
      The effect of the interaction, for example &quot;reduced gastric absorption of

      <short value="The effect of the interaction, for example &quot;reduced gastric absorption of
       primary medication&quot;"/> 
      The effect of the interaction, for example &quot;reduced gastric absorption of

      <definition value="The effect of the interaction, for example &quot;reduced gastric absorption of
       primary medication&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="InteractionEffect"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A interaction effect of clinical use of a medication or other substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-effect"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactions Effect"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.incidence">
      <path value="ClinicalUseDefinition.interaction.incidence"/> 
      <short value="The incidence of the interaction, e.g. theoretical, observed"/> 
      <definition value="The incidence of the interaction, e.g. theoretical, observed."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirableEffectSymptom"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for incidence of occurence of an interaction."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-incidence"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Interactions Incidence"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.interaction.management">
      <path value="ClinicalUseDefinition.interaction.management"/> 
      <short value="Actions for managing the interaction"/> 
      <definition value="Actions for managing the interaction."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="InteractionManagement"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A type of management for an interaction of a medication or other substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/interaction-management"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Interactions.Management Actions"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.population">
      <path value="ClinicalUseDefinition.population"/> 
      <short value="The population group to which this applies"/> 
      <definition value="The population group to which this applies."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="Reference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Group"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Population Specifics"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.library">
      <path value="ClinicalUseDefinition.library"/> 
      <short value="Logic used by the clinical use definition"/> 
      <definition value="Logic used by the clinical use definition."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="canonical"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Library"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect">
      <path value="ClinicalUseDefinition.undesirableEffect"/> 
      <short value="A possible negative outcome from the use of this treatment"/> 
      Describe the possible undesirable effects (negative outcomes) from the use of the

      <definition value="Describe the possible undesirable effects (negative outcomes) from the use of the
       medicinal product as treatment."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect">
      <path value="ClinicalUseDefinition.undesirableEffect.symptomConditionEffect"/> 
      <short value="The situation in which the undesirable effect may manifest"/> 
      <definition value="The situation in which the undesirable effect may manifest."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableReference"/> 
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/ObservationDefinition"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirableEffectSymptom"/> 
        </extension> 
        <strength value="example"/> 
        <description value="An undesirable effect of clinical use."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/undesirable-effect-symptom"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects.Undesirable Effect as &quot;Symptom / Condition / Effect&quot;"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.classification">
      <path value="ClinicalUseDefinition.undesirableEffect.classification"/> 
      <short value="High level classification of the effect"/> 
      <definition value="High level classification of the effect."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirableEffectClassification"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for an undesirable effect."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/undesirable-effect-classification"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects.Symptom / Condition / Effect Classification"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence">
      <path value="ClinicalUseDefinition.undesirableEffect.frequencyOfOccurrence"/> 
      <short value="How often the effect is seen"/> 
      <definition value="How often the effect is seen."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="UndesirablEffectFrequency"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A categorisation for a frequency of occurence of an undesirable effect."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/undesirable-effect-frequency"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="Undesirable Effects.Frequency of Occurrence"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning">
      <path value="ClinicalUseDefinition.warning"/> 
      Critical environmental, health or physical risks or hazards. For example 'Do not

      <short value="Critical environmental, health or physical risks or hazards. For example 'Do not
       operate heavy machinery', 'May cause drowsiness'"/> 
      A critical piece of information about environmental, health or physical risks or
       hazards that serve as caution to the user. For example 'Do not operate heavy machinery',

      <definition value="A critical piece of information about environmental, health or physical risks or
       hazards that serve as caution to the user. For example 'Do not operate heavy machinery',

       'May cause drowsiness', or 'Get medical advice/attention if you feel unwell'."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="BackboneElement"/> 
      </type> 
      <condition value="cud-1"/> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.description">
      <path value="ClinicalUseDefinition.warning.description"/> 
      <short value="A textual definition of this warning, with formatting"/> 
      <definition value="A textual definition of this warning, with formatting."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="markdown"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="ClinicalUseDefinition.warning.code">
      <path value="ClinicalUseDefinition.warning.code"/> 
      <short value="A coded or unformatted textual definition of this warning"/> 
      <definition value="A coded or unformatted textual definition of this warning."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <mustSupport value="false"/> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="WarningType"/> 
        </extension> 
        <strength value="example"/> 
        <description value="Classification of warning type."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/warning-type"/> 
      </binding> 
      <mapping> 
        <identity value="idmp"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
  </differential> 


</

StructureDefinition

>



Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.