11.6 Resource MedicationKnowledge - Content

Name	Flags	Card.	Type	Description & Constraints
MedicationKnowledge	TU		DomainResource	Definition of Medication Knowledge Elements defined in Ancestors: id , meta , implicitRules , language , text , contained , extension , modifierExtension Interfaces Implemented: MetadataResource
code identifier	Σ	0..1 0..*	CodeableConcept Identifier	Code that identifies Business identifier for this medication SNOMED CT Medication Codes ( Example )
status code	?! Σ	0..1	code CodeableConcept	active | inactive | entered-in-error Code that identifies this medication MedicationKnowledge Status Binding: SNOMED CT Medication Codes ( Required Example )
manufacturer status	?! Σ	0..1	Reference code	active | entered-in-error | inactive Binding: MedicationKnowledge Status Codes ( Organization Required ) Manufacturer of the item
doseForm author		0..1	CodeableConcept Reference ( Organization )	powder | tablets | capsule + Creator or owner of the knowledge or information about the medication SNOMED CT Form Codes ( Example )
amount intendedJurisdiction		0..1 0..*	SimpleQuantity CodeableConcept	Amount Codes that identify the different jurisdictions for which the information of drug in package this resource was created
synonym name	Σ	0..*	string	Additional names for a A name associated with the medication being described
relatedMedicationKnowledge		0..*	BackboneElement	Associated or related medication information
type		1..1	CodeableConcept	Category of medicationKnowledge
reference		1..*	Reference ( MedicationKnowledge )	Associated documentation about the associated medication knowledge
associatedMedication		0..*	Reference ( Medication )	A The set of medication resource resources that is are associated with this medication
productType		0..*	CodeableConcept	Category of the medication or product
monograph		0..*	BackboneElement	Associated documentation about the medication
type		0..1	CodeableConcept	The category of medication document
source		0..1	Reference ( DocumentReference | Media )	Associated documentation about the medication
ingredient preparationInstruction		0..* 0..1	BackboneElement markdown	Active or inactive ingredient The instructions for preparing the medication
item[x] cost		1..1 0..*	BackboneElement	Medication(s) or substance(s) contained in The pricing of the medication
itemCodeableConcept effectiveDate		0..*	CodeableConcept Period	The date range for which the cost is effective
itemReference type		1..1	Reference ( Substance CodeableConcept )	The category of the cost information
isActive source		0..1	boolean string	Active ingredient indicator The source or owner for the price information
strength cost[x]		0..1 1..1	Ratio	Quantity The price or category of ingredient present the cost of the medication Binding: Medication Cost Category Codes ( Example )
preparationInstruction costMoney		0..1	markdown Money
intendedRoute costCodeableConcept		0..*	CodeableConcept
cost monitoringProgram	Σ	0..*	BackboneElement	The pricing of the Program under which a medication is reviewed
type		1..1 0..1	CodeableConcept	The category Type of program under which the cost information medication is monitored
source name		0..1	string	The source or owner for Name of the price information reviewing program
cost indicationGuideline		1..1 0..*	Money BackboneElement	The price Guidelines or protocols for administration of the medication for an indication
monitoringProgram indication		0..*	BackboneElement CodeableReference ( ClinicalUseDefinition )	Program under which a medication is reviewed Indication for use that applies to the specific administration guideline
type dosingGuideline		0..1 0..*	CodeableConcept BackboneElement	Type Guidelines for dosage of program under which the medication is monitored
name treatmentIntent		0..1	string CodeableConcept	Name of the reviewing program administrationGuidelines 0..* BackboneElement Guidelines for administration Intention of the medication treatment
dosage		0..*	BackboneElement	Dosage for the medication for the specific guidelines
type		1..1	CodeableConcept	Category of dosage for a medication
dosage		1..*	Dosage	Dosage for the medication for the specific guidelines indication[x] 0..1
indicationCodeableConcept administrationTreatment		0..1	CodeableConcept	Type of treatment the guideline applies to
indicationReference patientCharacteristic		0..*	Reference ( ObservationDefinition BackboneElement )	Characteristics of the patient that are relevant to the administration guidelines
patientCharacteristics type		0..* 1..1	BackboneElement CodeableConcept	Characteristics Categorization of the patient specific characteristic that are is relevant to the administration guidelines guideline
characteristic[x] value[x]		1..1 0..1		Specific The specific characteristic that is relevant to the administration guideline
characteristicCodeableConcept valueCodeableConcept			CodeableConcept
characteristicQuantity valueQuantity			SimpleQuantity Quantity
value valueRange		0..*	string Range
medicineClassification		0..*	BackboneElement	Categorization of the medication within a formulary or classification system
type		1..1	CodeableConcept	The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
classification source[x]		0..1		0..* The source of the classification
sourceString			string
sourceUri			uri
classification		0..*	CodeableConcept	Specific category assigned to the medication
packaging	0..1	0..*	BackboneElement	Details about packaged medications
type cost		0..*	see cost	Cost of the packaged medication
packagedProduct		0..1	CodeableConcept Reference ( PackagedProductDefinition )	A code that defines the specific type of packaging that the The packaged medication can be found in that is being priced medicationKnowledge Package Type Codes
clinicalUseIssue		0..*	Reference ( Example ClinicalUseDefinition )	Potential clinical issue with or between medication(s)
storageGuideline quantity		0..*	BackboneElement	How the medication should be stored
reference		0..1	SimpleQuantity uri	The number of product units the package would contain if fully loaded Reference to additional information
drugCharacteristic note		0..*	BackboneElement Annotation	Specifies descriptive properties of the medicine Additional storage notes
type stabilityDuration		0..1	CodeableConcept Duration	Code specifying the type of characteristic of medication Duration remains stable medicationKnowledge Characteristic Codes ( Example )
value[x] environmentalSetting		0..1 0..*	BackboneElement	Description Setting or value of the characteristic environment for adequate storage
valueCodeableConcept type		1..1	CodeableConcept	Categorization of the setting
valueString value[x]		1..1	string	Value of the setting
valueQuantity			SimpleQuantity Quantity
valueBase64Binary valueRange			base64Binary Range
contraindication valueCodeableConcept		Reference ( DetectedIssue )	Potential clinical issue with or between medication(s) CodeableConcept
regulatory		0..*	BackboneElement	Regulatory information about a medication
regulatoryAuthority		1..1	Reference ( Organization )	Specifies the authority of the regulation
substitution		0..*	BackboneElement	Specifies if changes are allowed when dispensing a medication from a regulatory perspective
type		1..1	CodeableConcept	Specifies the type of substitution allowed
allowed		1..1	boolean	Specifies if regulation allows for changes in the medication when dispensing
schedule		0..*	BackboneElement CodeableConcept	Specifies the schedule of a medication in jurisdiction
schedule maxDispense		1..1 0..1	CodeableConcept BackboneElement	Specifies The maximum number of units of the specific drug schedule medication that can be dispensed in a period
maxDispense quantity		0..1 1..1	BackboneElement SimpleQuantity	The maximum number of units of the medication that can be dispensed in a period
quantity period		1..1 0..1	SimpleQuantity Duration	The period that applies to the maximum number of units of
definitional		0..1	BackboneElement	Minimal definition information about the medication that can be dispensed
period definition		0..*	Reference ( MedicinalProductDefinition )	Definitional resources that provide more information about this medication
doseForm		0..1	Duration CodeableConcept	The period that applies to the maximum number of units powder | tablets | capsule + Binding: SNOMED CT Form Codes ( Example )
kinetics intendedRoute		0..*	BackboneElement CodeableConcept	The time course of drug absorption, distribution, metabolism and excretion intended or approved route of a medication from the body administration Binding: SNOMED CT Route Codes ( Example )
areaUnderCurve ingredient	Σ	0..*	SimpleQuantity BackboneElement	The drug concentration measured at certain discrete points Active or inactive ingredient
item	Σ	1..1	CodeableReference ( Substance )	Substances contained in time the medication
lethalDose50 type		0..1	CodeableConcept	A code that defines the type of ingredient, active, base, etc Binding: RoleClassIngredientEntity ( Example )
strength[x]		0..1		Quantity of ingredient present Binding: Medication Ingredient Strength Codes ( Example )
strengthRatio			Ratio
strengthCodeableConcept			CodeableConcept
strengthQuantity			Quantity
drugCharacteristic		0..*	SimpleQuantity BackboneElement	The median lethal dose Specifies descriptive properties of a drug the medicine
halfLifePeriod type		0..1	CodeableConcept	Code specifying the type of characteristic of medication Binding: medicationKnowledge Characteristic Codes ( Example )
value[x]		0..1		Description of the characteristic
valueCodeableConcept		Duration	CodeableConcept
valueString			string
valueQuantity		Time required for concentration in the body to decrease by half	SimpleQuantity
valueBase64Binary			base64Binary
valueAttachment			Attachment
Documentation for this format

See the Extensions for this resource

<MedicationKnowledge xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <identifier><!-- 0..* Identifier Business identifier for this medication --></identifier>

 <code><!-- 0..1 CodeableConcept Code that identifies this medication --></code>
 <
 <</manufacturer>
 <</doseForm>
 <</amount>
 <
 <

 <status value="[code]"/><!-- 0..1 active | entered-in-error | inactive -->
 <author><!-- 0..1 Reference(Organization) Creator or owner of the knowledge or information about the medication --></author>
 <intendedJurisdiction><!-- 0..* CodeableConcept Codes that identify the different jurisdictions for which the information of this resource was created --></intendedJurisdiction>
 <name value="[string]"/><!-- 0..* A name associated with the medication being described -->
 <relatedMedicationKnowledge>  <!-- 0..* Associated or related medication information -->

  <type><!-- 1..1 CodeableConcept Category of medicationKnowledge --></type>
  <reference><!-- 1..* Reference(MedicationKnowledge) Associated documentation about the associated medication knowledge --></reference>
 </relatedMedicationKnowledge>
 <</associatedMedication>

 <associatedMedication><!-- 0..* Reference(Medication) The set of medication resources that are associated with this medication --></associatedMedication>

 <productType><!-- 0..* CodeableConcept Category of the medication or product --></productType>
 <monograph>  <!-- 0..* Associated documentation about the medication -->
  <type><!-- 0..1 CodeableConcept The category of medication document --></type>
  <</source>

  <source><!-- 0..1 Reference(DocumentReference) Associated documentation about the medication --></source>

 </monograph>
 <
  <</item[x]>
  <
  <</strength>
 </ingredient>

 <preparationInstruction value="[markdown]"/><!-- 0..1 The instructions for preparing the medication -->
 <</intendedRoute>

 <cost>  <!-- 0..* The pricing of the medication -->
  <effectiveDate><!-- 0..* Period The date range for which the cost is effective --></effectiveDate>

  <type><!-- 1..1 CodeableConcept The category of the cost information --></type>
  <source value="[string]"/><!-- 0..1 The source or owner for the price information -->
  <</cost>

  <cost[x]><!-- 1..1 Money|CodeableConcept The price or category of the cost of the medication --></cost[x]>

 </cost>
 <monitoringProgram>  <!-- 0..* Program under which a medication is reviewed -->
  <type><!-- 0..1 CodeableConcept Type of program under which the medication is monitored --></type>
  <name value="[string]"/><!-- 0..1 Name of the reviewing program -->
 </monitoringProgram>
 <
  <
   <</type>
   <</dosage>
  </dosage>
  <</indication[x]>
  <
   <</characteristic[x]>
   <
  </patientCharacteristics>
 </administrationGuidelines>

 <indicationGuideline>  <!-- 0..* Guidelines or protocols for administration of the medication for an indication -->
  <indication><!-- 0..* CodeableReference(ClinicalUseDefinition) Indication for use that applies to the specific administration guideline --></indication>
  <dosingGuideline>  <!-- 0..* Guidelines for dosage of the medication -->
   <treatmentIntent><!-- 0..1 CodeableConcept Intention of the treatment --></treatmentIntent>
   <dosage>  <!-- 0..* Dosage for the medication for the specific guidelines -->
    <type><!-- 1..1 CodeableConcept Category of dosage for a medication --></type>
    <dosage><!-- 1..* Dosage Dosage for the medication for the specific guidelines --></dosage>
   </dosage>
   <administrationTreatment><!-- 0..1 CodeableConcept Type of treatment the guideline applies to --></administrationTreatment>
   <patientCharacteristic>  <!-- 0..* Characteristics of the patient that are relevant to the administration guidelines -->
    <type><!-- 1..1 CodeableConcept Categorization of specific characteristic that is relevant to the administration guideline --></type>
    <value[x]><!-- 0..1 CodeableConcept|Quantity|Range The specific characteristic --></value[x]>
   </patientCharacteristic>
  </dosingGuideline>
 </indicationGuideline>

 <medicineClassification>  <!-- 0..* Categorization of the medication within a formulary or classification system -->
  <type><!-- 1..1 CodeableConcept The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification) --></type>
  <source[x]><!-- 0..1 string|uri The source of the classification --></source[x]>

  <classification><!-- 0..* CodeableConcept Specific category assigned to the medication --></classification>
 </medicineClassification>
 <
  <</type>
  <</quantity>

 <packaging>  <!-- 0..* Details about packaged medications -->
  <cost><!-- 0..* Content as for MedicationKnowledge.cost Cost of the packaged medication --></cost>
  <packagedProduct><!-- 0..1 Reference(PackagedProductDefinition) The packaged medication that is being priced --></packagedProduct>

 </packaging>
 <
  <</type>
  <)|
    </value[x]>
 </drugCharacteristic>
 <</contraindication>

 <clinicalUseIssue><!-- 0..* Reference(ClinicalUseDefinition) Potential clinical issue with or between medication(s) --></clinicalUseIssue>
 <storageGuideline>  <!-- 0..* How the medication should be stored -->
  <reference value="[uri]"/><!-- 0..1 Reference to additional information -->
  <note><!-- 0..* Annotation Additional storage notes --></note>
  <stabilityDuration><!-- 0..1 Duration Duration remains stable --></stabilityDuration>
  <environmentalSetting>  <!-- 0..* Setting or value of environment for adequate storage -->
   <type><!-- 1..1 CodeableConcept Categorization of the setting --></type>
   <value[x]><!-- 1..1 Quantity|Range|CodeableConcept Value of the setting --></value[x]>
  </environmentalSetting>
 </storageGuideline>

 <regulatory>  <!-- 0..* Regulatory information about a medication -->
  <regulatoryAuthority><!-- 1..1 Reference(Organization) Specifies the authority of the regulation --></regulatoryAuthority>
  <substitution>  <!-- 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective -->
   <type><!-- 1..1 CodeableConcept Specifies the type of substitution allowed --></type>
   <allowed value="[boolean]"/><!-- 1..1 Specifies if regulation allows for changes in the medication when dispensing -->
  </substitution>
  <
   <</schedule>
  </schedule>

  <schedule><!-- 0..* CodeableConcept Specifies the schedule of a medication in jurisdiction --></schedule>

  <maxDispense>  <!-- 0..1 The maximum number of units of the medication that can be dispensed in a period -->
   <quantity><!-- 1..1 Quantity(SimpleQuantity) The maximum number of units of the medication that can be dispensed --></quantity>
   <period><!-- 0..1 Duration The period that applies to the maximum number of units --></period>
  </maxDispense>
 </regulatory>
 <
  <</areaUnderCurve>
  <</lethalDose50>
  <</halfLifePeriod>
 </kinetics>

 <definitional>  <!-- 0..1 Minimal definition information about the medication -->
  <definition><!-- 0..* Reference(MedicinalProductDefinition) Definitional resources that provide more information about this medication --></definition>
  <doseForm><!-- 0..1 CodeableConcept powder | tablets | capsule + --></doseForm>
  <intendedRoute><!-- 0..* CodeableConcept The intended or approved route of administration --></intendedRoute>
  <ingredient>  <!-- 0..* Active or inactive ingredient -->
   <item><!-- 1..1 CodeableReference(Substance) Substances contained in the medication --></item>
   <type><!-- 0..1 CodeableConcept A code that defines the type of ingredient, active, base, etc  --></type>
   <strength[x]><!-- 0..1 Ratio|CodeableConcept|Quantity Quantity of ingredient present --></strength[x]>
  </ingredient>
  <drugCharacteristic>  <!-- 0..* Specifies descriptive properties of the medicine -->
   <type><!-- 0..1 CodeableConcept Code specifying the type of characteristic of medication --></type>
   <value[x]><!-- 0..1 CodeableConcept|string|Quantity(SimpleQuantity)|
     base64Binary|Attachment Description of the characteristic --></value[x]>

  </drugCharacteristic>
 </definitional>

</MedicationKnowledge>

{
  "resourceType" : "MedicationKnowledge",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "identifier" : [{ Identifier }], // Business identifier for this medication

  "code" : { CodeableConcept }, // Code that identifies this medication
  "
  "
  "
  "
  "
  "

  "status" : "<code>", // active | entered-in-error | inactive
  "author" : { Reference(Organization) }, // Creator or owner of the knowledge or information about the medication
  "intendedJurisdiction" : [{ CodeableConcept }], // Codes that identify the different jurisdictions for which the information of this resource was created
  "name" : ["<string>"], // A name associated with the medication being described
  "relatedMedicationKnowledge" : [{ // Associated or related medication information

    "type" : { CodeableConcept }, // R!  Category of medicationKnowledge
    "reference" : [{ Reference(MedicationKnowledge) }] // R!  Associated documentation about the associated medication knowledge
  }],
  "

  "associatedMedication" : [{ Reference(Medication) }], // The set of medication resources that are associated with this medication

  "productType" : [{ CodeableConcept }], // Category of the medication or product
  "monograph" : [{ // Associated documentation about the medication
    "type" : { CodeableConcept }, // The category of medication document
    "
  }],
  "
    
    " },
    " },
    "
    "

    "source" : { Reference(DocumentReference) } // Associated documentation about the medication

  }],
  "preparationInstruction" : "<markdown>", // The instructions for preparing the medication
  "

  "cost" : [{ // The pricing of the medication
    "effectiveDate" : [{ Period }], // The date range for which the cost is effective

    "type" : { CodeableConcept }, // R!  The category of the cost information
    "source" : "<string>", // The source or owner for the price information
    "

    // cost[x]: The price or category of the cost of the medication. One of these 2:
    "costMoney" : { Money },
    "costCodeableConcept" : { CodeableConcept }

  }],
  "monitoringProgram" : [{ // Program under which a medication is reviewed
    "type" : { CodeableConcept }, // Type of program under which the medication is monitored
    "name" : "<string>" // Name of the reviewing program
  }],
  "
    "
      "
      "
    }],
    
    " },
    " },
    "
      
      " },
      " },
      "

  "indicationGuideline" : [{ // Guidelines or protocols for administration of the medication for an indication
    "indication" : [{ CodeableReference(ClinicalUseDefinition) }], // Indication for use that applies to the specific administration guideline
    "dosingGuideline" : [{ // Guidelines for dosage of the medication
      "treatmentIntent" : { CodeableConcept }, // Intention of the treatment
      "dosage" : [{ // Dosage for the medication for the specific guidelines
        "type" : { CodeableConcept }, // R!  Category of dosage for a medication
        "dosage" : [{ Dosage }] // R!  Dosage for the medication for the specific guidelines
      }],
      "administrationTreatment" : { CodeableConcept }, // Type of treatment the guideline applies to
      "patientCharacteristic" : [{ // Characteristics of the patient that are relevant to the administration guidelines
        "type" : { CodeableConcept }, // R!  Categorization of specific characteristic that is relevant to the administration guideline
        // value[x]: The specific characteristic. One of these 3:

        "valueCodeableConcept" : { CodeableConcept },
        "valueQuantity" : { Quantity },
        "valueRange" : { Range }
      }]

    }]
  }],
  "medicineClassification" : [{ // Categorization of the medication within a formulary or classification system
    "type" : { CodeableConcept }, // R!  The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
    // source[x]: The source of the classification. One of these 2:
    "sourceString" : "<string>",
    "sourceUri" : "<uri>",

    "classification" : [{ CodeableConcept }] // Specific category assigned to the medication
  }],
  "
    "
    "
  },
  "
    "
    
    " }
    ">"
    " }
    ">"

  "packaging" : [{ // Details about packaged medications
    "cost" : [{ Content as for MedicationKnowledge.cost }], // Cost of the packaged medication
    "packagedProduct" : { Reference(PackagedProductDefinition) } // The packaged medication that is being priced
  }],
  "clinicalUseIssue" : [{ Reference(ClinicalUseDefinition) }], // Potential clinical issue with or between medication(s)
  "storageGuideline" : [{ // How the medication should be stored
    "reference" : "<uri>", // Reference to additional information
    "note" : [{ Annotation }], // Additional storage notes
    "stabilityDuration" : { Duration }, // Duration remains stable
    "environmentalSetting" : [{ // Setting or value of environment for adequate storage
      "type" : { CodeableConcept }, // R!  Categorization of the setting
      // value[x]: Value of the setting. One of these 3:

      "valueQuantity" : { Quantity },
      "valueRange" : { Range },
      "valueCodeableConcept" : { CodeableConcept }
    }]

  }],
  "

  "regulatory" : [{ // Regulatory information about a medication
    "regulatoryAuthority" : { Reference(Organization) }, // R!  Specifies the authority of the regulation
    "substitution" : [{ // Specifies if changes are allowed when dispensing a medication from a regulatory perspective
      "type" : { CodeableConcept }, // R!  Specifies the type of substitution allowed
      "allowed" : <boolean> // R!  Specifies if regulation allows for changes in the medication when dispensing
    }],
    "
      "
    }],

    "schedule" : [{ CodeableConcept }], // Specifies the schedule of a medication in jurisdiction

    "maxDispense" : { // The maximum number of units of the medication that can be dispensed in a period
      "quantity" : { Quantity(SimpleQuantity) }, // R!  The maximum number of units of the medication that can be dispensed
      "period" : { Duration } // The period that applies to the maximum number of units
    }
  }],
  "
    "
    "
    "
  }]

  "definitional" : { // Minimal definition information about the medication
    "definition" : [{ Reference(MedicinalProductDefinition) }], // Definitional resources that provide more information about this medication
    "doseForm" : { CodeableConcept }, // powder | tablets | capsule +
    "intendedRoute" : [{ CodeableConcept }], // The intended or approved route of administration
    "ingredient" : [{ // Active or inactive ingredient
      "item" : { CodeableReference(Substance) }, // R!  Substances contained in the medication
      "type" : { CodeableConcept }, // A code that defines the type of ingredient, active, base, etc 
      // strength[x]: Quantity of ingredient present. One of these 3:

      "strengthRatio" : { Ratio },
      "strengthCodeableConcept" : { CodeableConcept },
      "strengthQuantity" : { Quantity }
    }],
    "drugCharacteristic" : [{ // Specifies descriptive properties of the medicine
      "type" : { CodeableConcept }, // Code specifying the type of characteristic of medication
      // value[x]: Description of the characteristic. One of these 5:

      "valueCodeableConcept" : { CodeableConcept },
      "valueString" : "<string>",
      "valueQuantity" : { Quantity(SimpleQuantity) },
      "valueBase64Binary" : "<base64Binary>",
      "valueAttachment" : { Attachment }
    }]
  }

}

@prefix fhir: <http://hl7.org/fhir/> .


[ a fhir:MedicationKnowledge;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:
  fhir:
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  ], ...;
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  ], ...;
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    # . One of these 2
      fhir: ]
      fhir:) ]
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  ], ...;
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    ], ...;
    # . One of these 2
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      # . One of these 2
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    ], ...;
  ], ...;
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  ];
  fhir:
    fhir:
    # . One of these 4
      fhir: ]
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  ], ...;
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    ], ...;
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    ], ...;
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    ];
  ], ...;
  fhir:
    fhir:
    fhir:
    fhir:
  ], ...;

  fhir:identifier  ( [ Identifier ] ... ) ; # 0..* Business identifier for this medication
  fhir:code [ CodeableConcept ] ; # 0..1 Code that identifies this medication
  fhir:status [ code ] ; # 0..1 active | entered-in-error | inactive
  fhir:author [ Reference(Organization) ] ; # 0..1 Creator or owner of the knowledge or information about the medication
  fhir:intendedJurisdiction  ( [ CodeableConcept ] ... ) ; # 0..* Codes that identify the different jurisdictions for which the information of this resource was created
  fhir:name  ( [ string ] ... ) ; # 0..* A name associated with the medication being described
  fhir:relatedMedicationKnowledge ( [ # 0..* Associated or related medication information
    fhir:type [ CodeableConcept ] ; # 1..1 Category of medicationKnowledge
    fhir:reference  ( [ Reference(MedicationKnowledge) ] ... ) ; # 1..* Associated documentation about the associated medication knowledge
  ] ... ) ;
  fhir:associatedMedication  ( [ Reference(Medication) ] ... ) ; # 0..* The set of medication resources that are associated with this medication
  fhir:productType  ( [ CodeableConcept ] ... ) ; # 0..* Category of the medication or product
  fhir:monograph ( [ # 0..* Associated documentation about the medication
    fhir:type [ CodeableConcept ] ; # 0..1 The category of medication document
    fhir:source [ Reference(DocumentReference) ] ; # 0..1 Associated documentation about the medication
  ] ... ) ;
  fhir:preparationInstruction [ markdown ] ; # 0..1 The instructions for preparing the medication
  fhir:cost ( [ # 0..* The pricing of the medication
    fhir:effectiveDate  ( [ Period ] ... ) ; # 0..* The date range for which the cost is effective
    fhir:type [ CodeableConcept ] ; # 1..1 The category of the cost information
    fhir:source [ string ] ; # 0..1 The source or owner for the price information
    # cost[x] : 1..1 The price or category of the cost of the medication. One of these 2
      fhir:cost [  a fhir:Money ; Money ]
      fhir:cost [  a fhir:CodeableConcept ; CodeableConcept ]
  ] ... ) ;
  fhir:monitoringProgram ( [ # 0..* Program under which a medication is reviewed
    fhir:type [ CodeableConcept ] ; # 0..1 Type of program under which the medication is monitored
    fhir:name [ string ] ; # 0..1 Name of the reviewing program
  ] ... ) ;
  fhir:indicationGuideline ( [ # 0..* Guidelines or protocols for administration of the medication for an indication
    fhir:indication  ( [ CodeableReference(ClinicalUseDefinition) ] ... ) ; # 0..* Indication for use that applies to the specific administration guideline
    fhir:dosingGuideline ( [ # 0..* Guidelines for dosage of the medication
      fhir:treatmentIntent [ CodeableConcept ] ; # 0..1 Intention of the treatment
      fhir:dosage ( [ # 0..* Dosage for the medication for the specific guidelines
        fhir:type [ CodeableConcept ] ; # 1..1 Category of dosage for a medication
        fhir:dosage  ( [ Dosage ] ... ) ; # 1..* Dosage for the medication for the specific guidelines
      ] ... ) ;
      fhir:administrationTreatment [ CodeableConcept ] ; # 0..1 Type of treatment the guideline applies to
      fhir:patientCharacteristic ( [ # 0..* Characteristics of the patient that are relevant to the administration guidelines
        fhir:type [ CodeableConcept ] ; # 1..1 Categorization of specific characteristic that is relevant to the administration guideline
        # value[x] : 0..1 The specific characteristic. One of these 3
          fhir:value [  a fhir:CodeableConcept ; CodeableConcept ]
          fhir:value [  a fhir:Quantity ; Quantity ]
          fhir:value [  a fhir:Range ; Range ]
      ] ... ) ;
    ] ... ) ;
  ] ... ) ;
  fhir:medicineClassification ( [ # 0..* Categorization of the medication within a formulary or classification system
    fhir:type [ CodeableConcept ] ; # 1..1 The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
    # source[x] : 0..1 The source of the classification. One of these 2
      fhir:source [  a fhir:string ; string ]
      fhir:source [  a fhir:uri ; uri ]
    fhir:classification  ( [ CodeableConcept ] ... ) ; # 0..* Specific category assigned to the medication
  ] ... ) ;
  fhir:packaging ( [ # 0..* Details about packaged medications
    fhir:cost  ( [ See MedicationKnowledge.cost ] ... ) ; # 0..* Cost of the packaged medication
    fhir:packagedProduct [ Reference(PackagedProductDefinition) ] ; # 0..1 The packaged medication that is being priced
  ] ... ) ;
  fhir:clinicalUseIssue  ( [ Reference(ClinicalUseDefinition) ] ... ) ; # 0..* Potential clinical issue with or between medication(s)
  fhir:storageGuideline ( [ # 0..* How the medication should be stored
    fhir:reference [ uri ] ; # 0..1 Reference to additional information
    fhir:note  ( [ Annotation ] ... ) ; # 0..* Additional storage notes
    fhir:stabilityDuration [ Duration ] ; # 0..1 Duration remains stable
    fhir:environmentalSetting ( [ # 0..* Setting or value of environment for adequate storage
      fhir:type [ CodeableConcept ] ; # 1..1 Categorization of the setting
      # value[x] : 1..1 Value of the setting. One of these 3
        fhir:value [  a fhir:Quantity ; Quantity ]
        fhir:value [  a fhir:Range ; Range ]
        fhir:value [  a fhir:CodeableConcept ; CodeableConcept ]
    ] ... ) ;
  ] ... ) ;
  fhir:regulatory ( [ # 0..* Regulatory information about a medication
    fhir:regulatoryAuthority [ Reference(Organization) ] ; # 1..1 Specifies the authority of the regulation
    fhir:substitution ( [ # 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective
      fhir:type [ CodeableConcept ] ; # 1..1 Specifies the type of substitution allowed
      fhir:allowed [ boolean ] ; # 1..1 Specifies if regulation allows for changes in the medication when dispensing
    ] ... ) ;
    fhir:schedule  ( [ CodeableConcept ] ... ) ; # 0..* Specifies the schedule of a medication in jurisdiction
    fhir:maxDispense [ # 0..1 The maximum number of units of the medication that can be dispensed in a period
      fhir:quantity [ Quantity(SimpleQuantity) ] ; # 1..1 The maximum number of units of the medication that can be dispensed
      fhir:period [ Duration ] ; # 0..1 The period that applies to the maximum number of units
    ] ;
  ] ... ) ;
  fhir:definitional [ # 0..1 Minimal definition information about the medication
    fhir:definition  ( [ Reference(MedicinalProductDefinition) ] ... ) ; # 0..* Definitional resources that provide more information about this medication
    fhir:doseForm [ CodeableConcept ] ; # 0..1 powder | tablets | capsule +
    fhir:intendedRoute  ( [ CodeableConcept ] ... ) ; # 0..* The intended or approved route of administration
    fhir:ingredient ( [ # 0..* Active or inactive ingredient
      fhir:item [ CodeableReference(Substance) ] ; # 1..1 Substances contained in the medication
      fhir:type [ CodeableConcept ] ; # 0..1 A code that defines the type of ingredient, active, base, etc
      # strength[x] : 0..1 Quantity of ingredient present. One of these 3
        fhir:strength [  a fhir:Ratio ; Ratio ]
        fhir:strength [  a fhir:CodeableConcept ; CodeableConcept ]
        fhir:strength [  a fhir:Quantity ; Quantity ]
    ] ... ) ;
    fhir:drugCharacteristic ( [ # 0..* Specifies descriptive properties of the medicine
      fhir:type [ CodeableConcept ] ; # 0..1 Code specifying the type of characteristic of medication
      # value[x] : 0..1 Description of the characteristic. One of these 5
        fhir:value [  a fhir:CodeableConcept ; CodeableConcept ]
        fhir:value [  a fhir:string ; string ]
        fhir:value [  a fhir:SimpleQuantity ; Quantity(SimpleQuantity) ]
        fhir:value [  a fhir:base64Binary ; base64Binary ]
        fhir:value [  a fhir:Attachment ; Attachment ]
    ] ... ) ;
  ] ;

]

See the Full Difference for further information

This analysis is available as XML or JSON .

Name	Flags	Card.	Type	Description & Constraints
MedicationKnowledge	TU		DomainResource	Definition of Medication Knowledge Elements defined in Ancestors: id , meta , implicitRules , language , text , contained , extension , modifierExtension Interfaces Implemented: MetadataResource
code identifier	Σ	0..1 0..*	CodeableConcept Identifier	Code that identifies Business identifier for this medication SNOMED CT Medication Codes ( Example )
status code	?! Σ	0..1	code CodeableConcept	active | inactive | entered-in-error Code that identifies this medication MedicationKnowledge Status Binding: SNOMED CT Medication Codes ( Required Example )
manufacturer status	?! Σ	0..1	Reference code	active | entered-in-error | inactive Binding: MedicationKnowledge Status Codes ( Organization Required ) Manufacturer of the item
doseForm author		0..1	CodeableConcept Reference ( Organization )	powder | tablets | capsule + Creator or owner of the knowledge or information about the medication SNOMED CT Form Codes ( Example )
amount intendedJurisdiction		0..1 0..*	SimpleQuantity CodeableConcept	Amount Codes that identify the different jurisdictions for which the information of drug in package this resource was created
synonym name	Σ	0..*	string	Additional names for a A name associated with the medication being described
relatedMedicationKnowledge		0..*	BackboneElement	Associated or related medication information
type		1..1	CodeableConcept	Category of medicationKnowledge
reference		1..*	Reference ( MedicationKnowledge )	Associated documentation about the associated medication knowledge
associatedMedication		0..*	Reference ( Medication )	A The set of medication resource resources that is are associated with this medication
productType		0..*	CodeableConcept	Category of the medication or product
monograph		0..*	BackboneElement	Associated documentation about the medication
type		0..1	CodeableConcept	The category of medication document
source		0..1	Reference ( DocumentReference | Media )	Associated documentation about the medication
ingredient preparationInstruction		0..* 0..1	BackboneElement markdown	Active or inactive ingredient The instructions for preparing the medication
item[x] cost		1..1 0..*	BackboneElement	Medication(s) or substance(s) contained in The pricing of the medication
itemCodeableConcept effectiveDate		0..*	CodeableConcept Period	The date range for which the cost is effective
itemReference type		1..1	Reference ( Substance CodeableConcept )	The category of the cost information
isActive source		0..1	boolean string	Active ingredient indicator The source or owner for the price information
strength cost[x]		0..1 1..1	Ratio	Quantity The price or category of ingredient present the cost of the medication Binding: Medication Cost Category Codes ( Example )
preparationInstruction costMoney		0..1	markdown Money
intendedRoute costCodeableConcept		0..*	CodeableConcept
cost monitoringProgram	Σ	0..*	BackboneElement	The pricing of the Program under which a medication is reviewed
type		1..1 0..1	CodeableConcept	The category Type of program under which the cost information medication is monitored
source name		0..1	string	The source or owner for Name of the price information reviewing program
cost indicationGuideline		1..1 0..*	Money BackboneElement	The price Guidelines or protocols for administration of the medication for an indication
monitoringProgram indication		0..*	BackboneElement CodeableReference ( ClinicalUseDefinition )	Program under which a medication is reviewed Indication for use that applies to the specific administration guideline
type dosingGuideline		0..1 0..*	CodeableConcept BackboneElement	Type Guidelines for dosage of program under which the medication is monitored
name treatmentIntent		0..1	string CodeableConcept	Name of the reviewing program administrationGuidelines 0..* BackboneElement Guidelines for administration Intention of the medication treatment
dosage		0..*	BackboneElement	Dosage for the medication for the specific guidelines
type		1..1	CodeableConcept	Category of dosage for a medication
dosage		1..*	Dosage	Dosage for the medication for the specific guidelines indication[x] 0..1
indicationCodeableConcept administrationTreatment		0..1	CodeableConcept	Type of treatment the guideline applies to
indicationReference patientCharacteristic		0..*	Reference ( ObservationDefinition BackboneElement )	Characteristics of the patient that are relevant to the administration guidelines
patientCharacteristics type		0..* 1..1	BackboneElement CodeableConcept	Characteristics Categorization of the patient specific characteristic that are is relevant to the administration guidelines guideline
characteristic[x] value[x]		1..1 0..1		Specific The specific characteristic that is relevant to the administration guideline
characteristicCodeableConcept valueCodeableConcept			CodeableConcept
characteristicQuantity valueQuantity			SimpleQuantity Quantity
value valueRange		0..*	string Range
medicineClassification		0..*	BackboneElement	Categorization of the medication within a formulary or classification system
type		1..1	CodeableConcept	The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
classification source[x]		0..1		0..* The source of the classification
sourceString			string
sourceUri			uri
classification		0..*	CodeableConcept	Specific category assigned to the medication
packaging	0..1	0..*	BackboneElement	Details about packaged medications
type cost		0..*	see cost	Cost of the packaged medication
packagedProduct		0..1	CodeableConcept Reference ( PackagedProductDefinition )	A code that defines the specific type of packaging that the The packaged medication can be found in that is being priced medicationKnowledge Package Type Codes
clinicalUseIssue		0..*	Reference ( Example ClinicalUseDefinition )	Potential clinical issue with or between medication(s)
storageGuideline quantity		0..*	BackboneElement	How the medication should be stored
reference		0..1	SimpleQuantity uri	The number of product units the package would contain if fully loaded Reference to additional information
drugCharacteristic note		0..*	BackboneElement Annotation	Specifies descriptive properties of the medicine Additional storage notes
type stabilityDuration		0..1	CodeableConcept Duration	Code specifying the type of characteristic of medication Duration remains stable medicationKnowledge Characteristic Codes ( Example )
value[x] environmentalSetting		0..1 0..*	BackboneElement	Description Setting or value of the characteristic environment for adequate storage
valueCodeableConcept type		1..1	CodeableConcept	Categorization of the setting
valueString value[x]		1..1	string	Value of the setting
valueQuantity			SimpleQuantity Quantity
valueBase64Binary valueRange			base64Binary Range
contraindication valueCodeableConcept		Reference ( DetectedIssue )	Potential clinical issue with or between medication(s) CodeableConcept
regulatory		0..*	BackboneElement	Regulatory information about a medication
regulatoryAuthority		1..1	Reference ( Organization )	Specifies the authority of the regulation
substitution		0..*	BackboneElement	Specifies if changes are allowed when dispensing a medication from a regulatory perspective
type		1..1	CodeableConcept	Specifies the type of substitution allowed
allowed		1..1	boolean	Specifies if regulation allows for changes in the medication when dispensing
schedule		0..*	BackboneElement CodeableConcept	Specifies the schedule of a medication in jurisdiction
schedule maxDispense		1..1 0..1	CodeableConcept BackboneElement	Specifies The maximum number of units of the specific drug schedule medication that can be dispensed in a period
maxDispense quantity		0..1 1..1	BackboneElement SimpleQuantity	The maximum number of units of the medication that can be dispensed in a period
quantity period		1..1 0..1	SimpleQuantity Duration	The period that applies to the maximum number of units of
definitional		0..1	BackboneElement	Minimal definition information about the medication that can be dispensed
period definition		0..*	Reference ( MedicinalProductDefinition )	Definitional resources that provide more information about this medication
doseForm		0..1	Duration CodeableConcept	The period that applies to the maximum number of units powder | tablets | capsule + Binding: SNOMED CT Form Codes ( Example )
kinetics intendedRoute		0..*	BackboneElement CodeableConcept	The time course of drug absorption, distribution, metabolism and excretion intended or approved route of a medication from the body administration Binding: SNOMED CT Route Codes ( Example )
areaUnderCurve ingredient	Σ	0..*	SimpleQuantity BackboneElement	The drug concentration measured at certain discrete points Active or inactive ingredient
item	Σ	1..1	CodeableReference ( Substance )	Substances contained in time the medication
lethalDose50 type		0..1	CodeableConcept	A code that defines the type of ingredient, active, base, etc Binding: RoleClassIngredientEntity ( Example )
strength[x]		0..1		Quantity of ingredient present Binding: Medication Ingredient Strength Codes ( Example )
strengthRatio			Ratio
strengthCodeableConcept			CodeableConcept
strengthQuantity			Quantity
drugCharacteristic		0..*	SimpleQuantity BackboneElement	The median lethal dose Specifies descriptive properties of a drug the medicine
halfLifePeriod type		0..1	CodeableConcept	Code specifying the type of characteristic of medication Binding: medicationKnowledge Characteristic Codes ( Example )
value[x]		0..1		Description of the characteristic
valueCodeableConcept		Duration	CodeableConcept
valueString			string
valueQuantity		Time required for concentration in the body to decrease by half	SimpleQuantity
valueBase64Binary			base64Binary
valueAttachment			Attachment
Documentation for this format

See the Extensions for this resource

<MedicationKnowledge xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <identifier><!-- 0..* Identifier Business identifier for this medication --></identifier>

 <code><!-- 0..1 CodeableConcept Code that identifies this medication --></code>
 <
 <</manufacturer>
 <</doseForm>
 <</amount>
 <
 <

 <status value="[code]"/><!-- 0..1 active | entered-in-error | inactive -->
 <author><!-- 0..1 Reference(Organization) Creator or owner of the knowledge or information about the medication --></author>
 <intendedJurisdiction><!-- 0..* CodeableConcept Codes that identify the different jurisdictions for which the information of this resource was created --></intendedJurisdiction>
 <name value="[string]"/><!-- 0..* A name associated with the medication being described -->
 <relatedMedicationKnowledge>  <!-- 0..* Associated or related medication information -->

  <type><!-- 1..1 CodeableConcept Category of medicationKnowledge --></type>
  <reference><!-- 1..* Reference(MedicationKnowledge) Associated documentation about the associated medication knowledge --></reference>
 </relatedMedicationKnowledge>
 <</associatedMedication>

 <associatedMedication><!-- 0..* Reference(Medication) The set of medication resources that are associated with this medication --></associatedMedication>

 <productType><!-- 0..* CodeableConcept Category of the medication or product --></productType>
 <monograph>  <!-- 0..* Associated documentation about the medication -->
  <type><!-- 0..1 CodeableConcept The category of medication document --></type>
  <</source>

  <source><!-- 0..1 Reference(DocumentReference) Associated documentation about the medication --></source>

 </monograph>
 <
  <</item[x]>
  <
  <</strength>
 </ingredient>

 <preparationInstruction value="[markdown]"/><!-- 0..1 The instructions for preparing the medication -->
 <</intendedRoute>

 <cost>  <!-- 0..* The pricing of the medication -->
  <effectiveDate><!-- 0..* Period The date range for which the cost is effective --></effectiveDate>

  <type><!-- 1..1 CodeableConcept The category of the cost information --></type>
  <source value="[string]"/><!-- 0..1 The source or owner for the price information -->
  <</cost>

  <cost[x]><!-- 1..1 Money|CodeableConcept The price or category of the cost of the medication --></cost[x]>

 </cost>
 <monitoringProgram>  <!-- 0..* Program under which a medication is reviewed -->
  <type><!-- 0..1 CodeableConcept Type of program under which the medication is monitored --></type>
  <name value="[string]"/><!-- 0..1 Name of the reviewing program -->
 </monitoringProgram>
 <
  <
   <</type>
   <</dosage>
  </dosage>
  <</indication[x]>
  <
   <</characteristic[x]>
   <
  </patientCharacteristics>
 </administrationGuidelines>

 <indicationGuideline>  <!-- 0..* Guidelines or protocols for administration of the medication for an indication -->
  <indication><!-- 0..* CodeableReference(ClinicalUseDefinition) Indication for use that applies to the specific administration guideline --></indication>
  <dosingGuideline>  <!-- 0..* Guidelines for dosage of the medication -->
   <treatmentIntent><!-- 0..1 CodeableConcept Intention of the treatment --></treatmentIntent>
   <dosage>  <!-- 0..* Dosage for the medication for the specific guidelines -->
    <type><!-- 1..1 CodeableConcept Category of dosage for a medication --></type>
    <dosage><!-- 1..* Dosage Dosage for the medication for the specific guidelines --></dosage>
   </dosage>
   <administrationTreatment><!-- 0..1 CodeableConcept Type of treatment the guideline applies to --></administrationTreatment>
   <patientCharacteristic>  <!-- 0..* Characteristics of the patient that are relevant to the administration guidelines -->
    <type><!-- 1..1 CodeableConcept Categorization of specific characteristic that is relevant to the administration guideline --></type>
    <value[x]><!-- 0..1 CodeableConcept|Quantity|Range The specific characteristic --></value[x]>
   </patientCharacteristic>
  </dosingGuideline>
 </indicationGuideline>

 <medicineClassification>  <!-- 0..* Categorization of the medication within a formulary or classification system -->
  <type><!-- 1..1 CodeableConcept The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification) --></type>
  <source[x]><!-- 0..1 string|uri The source of the classification --></source[x]>

  <classification><!-- 0..* CodeableConcept Specific category assigned to the medication --></classification>
 </medicineClassification>
 <
  <</type>
  <</quantity>

 <packaging>  <!-- 0..* Details about packaged medications -->
  <cost><!-- 0..* Content as for MedicationKnowledge.cost Cost of the packaged medication --></cost>
  <packagedProduct><!-- 0..1 Reference(PackagedProductDefinition) The packaged medication that is being priced --></packagedProduct>

 </packaging>
 <
  <</type>
  <)|
    </value[x]>
 </drugCharacteristic>
 <</contraindication>

 <clinicalUseIssue><!-- 0..* Reference(ClinicalUseDefinition) Potential clinical issue with or between medication(s) --></clinicalUseIssue>
 <storageGuideline>  <!-- 0..* How the medication should be stored -->
  <reference value="[uri]"/><!-- 0..1 Reference to additional information -->
  <note><!-- 0..* Annotation Additional storage notes --></note>
  <stabilityDuration><!-- 0..1 Duration Duration remains stable --></stabilityDuration>
  <environmentalSetting>  <!-- 0..* Setting or value of environment for adequate storage -->
   <type><!-- 1..1 CodeableConcept Categorization of the setting --></type>
   <value[x]><!-- 1..1 Quantity|Range|CodeableConcept Value of the setting --></value[x]>
  </environmentalSetting>
 </storageGuideline>

 <regulatory>  <!-- 0..* Regulatory information about a medication -->
  <regulatoryAuthority><!-- 1..1 Reference(Organization) Specifies the authority of the regulation --></regulatoryAuthority>
  <substitution>  <!-- 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective -->
   <type><!-- 1..1 CodeableConcept Specifies the type of substitution allowed --></type>
   <allowed value="[boolean]"/><!-- 1..1 Specifies if regulation allows for changes in the medication when dispensing -->
  </substitution>
  <
   <</schedule>
  </schedule>

  <schedule><!-- 0..* CodeableConcept Specifies the schedule of a medication in jurisdiction --></schedule>

  <maxDispense>  <!-- 0..1 The maximum number of units of the medication that can be dispensed in a period -->
   <quantity><!-- 1..1 Quantity(SimpleQuantity) The maximum number of units of the medication that can be dispensed --></quantity>
   <period><!-- 0..1 Duration The period that applies to the maximum number of units --></period>
  </maxDispense>
 </regulatory>
 <
  <</areaUnderCurve>
  <</lethalDose50>
  <</halfLifePeriod>
 </kinetics>

 <definitional>  <!-- 0..1 Minimal definition information about the medication -->
  <definition><!-- 0..* Reference(MedicinalProductDefinition) Definitional resources that provide more information about this medication --></definition>
  <doseForm><!-- 0..1 CodeableConcept powder | tablets | capsule + --></doseForm>
  <intendedRoute><!-- 0..* CodeableConcept The intended or approved route of administration --></intendedRoute>
  <ingredient>  <!-- 0..* Active or inactive ingredient -->
   <item><!-- 1..1 CodeableReference(Substance) Substances contained in the medication --></item>
   <type><!-- 0..1 CodeableConcept A code that defines the type of ingredient, active, base, etc  --></type>
   <strength[x]><!-- 0..1 Ratio|CodeableConcept|Quantity Quantity of ingredient present --></strength[x]>
  </ingredient>
  <drugCharacteristic>  <!-- 0..* Specifies descriptive properties of the medicine -->
   <type><!-- 0..1 CodeableConcept Code specifying the type of characteristic of medication --></type>
   <value[x]><!-- 0..1 CodeableConcept|string|Quantity(SimpleQuantity)|
     base64Binary|Attachment Description of the characteristic --></value[x]>

  </drugCharacteristic>
 </definitional>

</MedicationKnowledge>