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Observation-example-f205-egfr.ttl

Example Observation/f205 (Turtle)

Maturity Level : N/A
Responsible Owner: Orders and Observations Work Group Standards Status : Informative Compartments : Device , Encounter , Group , Patient , Practitioner , RelatedPerson

Raw Turtle (+ also see Turtle/RDF Format Specification )

Real-world patient - estimated gfr 

@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .

@prefix loinc: <https://loinc.org/rdf/> .

@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/Observation/f205> a fhir:Observation;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "f205"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: f205</p><p><b>identifier</b>: 1304-03720-eGFR</p><p><b>status</b>: final</p><p><b>code</b>: Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span>(Details : {LOINC code '33914-3' = 'Glomerular filtration rate/1.73 sq M.predicted by Creatinine-based formula (MDRD)', given as 'Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)'})</span></p><p><b>subject</b>: <a>Roel</a></p><p><b>issued</b>: 04/04/2013 2:34:00 PM</p><p><b>performer</b>: <a>Luigi Maas</a></p><p><b>interpretation</b>: interpretation of results should be assigned based upon the level of kindey function <span>(Details )</span></p><p><b>note</b>: GFR estimating equations developed by the Modification of Diet in Renal Disease (MDRD) Study Group and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)....</p><p><b>method</b>: MDRD <span>(Details : {SNOMED CT code '702668005' = 'Modification of diet in renal disease formula', given as 'MDRD'})</span></p><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M predicted among blacks [Volume Rate/?Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span>(Details : {LOINC code '48643-1' = 'Glomerular filtration rate/1.73 sq M predicted among blacks by Creatinine-based formula (MDRD)', given as 'Glomerular filtration rate/1.73 sq M predicted among blacks [Volume Rate/?Area] in Serum or Plasma by Creatinine-based formula (MDRD)'})</span></p><p><b>value</b>: &gt;60 mL/min/1.73m2<span> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table><tr><td>-</td></tr><tr><td>*</td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: Glomerular filtration rate/1.73 sq M predicted among non-blacks [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD) <span>(Details : {LOINC code '48642-3' = 'Glomerular filtration rate/1.73 sq M predicted among non-blacks by Creatinine-based formula (MDRD)', given as 'Glomerular filtration rate/1.73 sq M predicted among non-blacks [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)'})</span></p><p><b>value</b>: 60 mL/min/1.73m2<span> (Details: UCUM code mL/min/{1.73_m2} = 'mL/min/{1.73_m2}')</span></p><h3>ReferenceRanges</h3><table><tr><td>-</td></tr><tr><td>*</td></tr></table></blockquote></div>"
  ];
  fhir:Observation.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "https://intranet.aumc.nl/labvalues" ];
     fhir:Identifier.value [ fhir:value "1304-03720-eGFR" ]
  ];
  fhir:Observation.status [ fhir:value "final"];
  fhir:Observation.code [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a loinc:33914-3;
       fhir:Coding.system [ fhir:value "http://loinc.org" ];
       fhir:Coding.code [ fhir:value "33914-3" ];
       fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]
     ]
  ];
  fhir:Observation.subject [
     fhir:link <http://hl7.org/fhir/Patient/f201>;
     fhir:Reference.reference [ fhir:value "Patient/f201" ];
     fhir:Reference.display [ fhir:value "Roel" ]
  ];
  fhir:Observation.issued [ fhir:value "2013-04-04T14:34:00+01:00"^^xsd:dateTime];
  fhir:Observation.performer [
     fhir:index 0;
     fhir:link <http://hl7.org/fhir/Practitioner/f202>;
     fhir:Reference.reference [ fhir:value "Practitioner/f202" ];
     fhir:Reference.display [ fhir:value "Luigi Maas" ]
  ];
  fhir:Observation.interpretation [
     fhir:index 0;
     fhir:CodeableConcept.text [ fhir:value "interpretation of results should be assigned based upon the level of kindey function" ]
  ];
  fhir:Observation.note [
     fhir:index 0;
     fhir:Annotation.text [ fhir:value "GFR estimating equations developed by the Modification of Diet in Renal Disease (MDRD) Study Group and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)...." ]
  ];
  fhir:Observation.method [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a sct:702668005;
       fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
       fhir:Coding.code [ fhir:value "702668005" ];
       fhir:Coding.display [ fhir:value "MDRD" ]
     ]
  ];
  fhir:Observation.component [
     fhir:index 0;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a loinc:48643-1;
         fhir:Coding.system [ fhir:value "http://loinc.org" ];
         fhir:Coding.code [ fhir:value "48643-1" ];
         fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M predicted among blacks [Volume Rate/?Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]
       ]
     ];
     fhir:Observation.component.valueQuantity [
       fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
       fhir:Quantity.comparator [ fhir:value ">" ];
       fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
     ];
     fhir:Observation.component.referenceRange [
       fhir:index 0;
       fhir:Observation.referenceRange.low [
         fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
       ];
       fhir:Observation.referenceRange.appliesTo [
         fhir:index 0;
         fhir:CodeableConcept.text [ fhir:value "non-black/african-american" ]
       ];
       fhir:Observation.referenceRange.age [
         fhir:Range.low [
           fhir:Quantity.value [ fhir:value "18"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "yrs" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "a" ]

<http://hl7.org/fhir/Observation/f205> a fhir:Observation ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "f205"] ; # 
  fhir:identifier ( [
     fhir:system [
       fhir:v "https://intranet.aumc.nl/labvalues"^^xsd:anyURI ;
       fhir:l <https://intranet.aumc.nl/labvalues>
     ] ;
     fhir:value [ fhir:v "1304-03720-eGFR" ] #    Does not exist   
  ] ) ; # 
  fhir:status [ fhir:v "final"] ; #    eGFR was measured on April fourth   
  fhir:code [
     fhir:coding ( [
       a loinc:33914-3 ;
       fhir:system [
         fhir:v "http://loinc.org"^^xsd:anyURI ;
         fhir:l <http://loinc.org>
       ] ;
       fhir:code [ fhir:v "33914-3" ] ;
       fhir:display [ fhir:v "Glomerular filtration rate [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)/1.73 sq M" ]
     ] ) #    Kind of observation = eGFR   
  ] ; # 
  fhir:subject [
     fhir:l <http://hl7.org/fhir/Patient/f201> ;
     fhir:reference [ fhir:v "Patient/f201" ] ;
     fhir:display [ fhir:v "Roel" ]
  ] ; # 
  fhir:issued [ fhir:v "2013-04-04T14:34:00+01:00"^^xsd:dateTime] ; # 
  fhir:performer ( [
     fhir:l <http://hl7.org/fhir/Practitioner/f202> ;
     fhir:reference [ fhir:v "Practitioner/f202" ] ;
     fhir:display [ fhir:v "Luigi Maas" ]
  ] ) ; # 
  fhir:interpretation ( [
     fhir:text [ fhir:v "interpretation of results should be assigned based upon the level of kindey function" ]
  ] ) ; #   no value element since have only component values and unable to interpret results needs clinical interpretation  
  fhir:note ( [
     fhir:text [ fhir:v "GFR estimating equations developed by the Modification of Diet in Renal Disease (MDRD) Study Group and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)...." ]
  ] ) ; # 
  fhir:method [
     fhir:coding ( [
       a sct:702668005 ;
       fhir:system [
         fhir:v "http://snomed.info/sct"^^xsd:anyURI ;
         fhir:l <http://snomed.info/sct>
       ] ;
       fhir:code [ fhir:v "702668005" ] ;
       fhir:display [ fhir:v "MDRD" ]
     ] ) #    Method was MDRD   
  ] ; #    The observation is complete   ,    No reliability concerns   
  fhir:component ( [
     fhir:code [
       fhir:coding ( [
         a loinc:48643-1 ;
         fhir:system [
           fhir:v "http://loinc.org"^^xsd:anyURI ;
           fhir:l <http://loinc.org>
         ] ;
         fhir:code [ fhir:v "48643-1" ] ;
         fhir:display [ fhir:v "Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M among black population" ]
       ] ) #    Kind of observation = eGFR for AA   
     ] ;
     fhir:value [
       a fhir:Quantity ;
       fhir:value [ fhir:v "60"^^xsd:decimal ] ; #    eGFR=54mL\/min\/1.73m2   
       fhir:comparator [ fhir:v ">" ] ;
       fhir:unit [ fhir:v "mL/min/1.73m2" ] ;
       fhir:system [
         fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
         fhir:l <http://unitsofmeasure.org>
       ] ;
       fhir:code [ fhir:v "mL/min/{1.73_m2}" ]
     ] ;
     fhir:referenceRange ( [
       fhir:low [
         fhir:value [ fhir:v "60"^^xsd:decimal ] ;
         fhir:unit [ fhir:v "mL/min/1.73m2" ] ;
         fhir:system [
           fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
           fhir:l <http://unitsofmeasure.org>
         ] ;
         fhir:code [ fhir:v "mL/min/{1.73_m2}" ]
       ] ;
       fhir:appliesTo ( [
         fhir:text [ fhir:v "non-black/african-american" ]
       ] ) ;
       fhir:age [
         fhir:low [
           fhir:value [ fhir:v "18"^^xsd:decimal ] ;
           fhir:unit [ fhir:v "yrs" ] ;
           fhir:system [
             fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
             fhir:l <http://unitsofmeasure.org>
           ] ;
           fhir:code [ fhir:v "a" ]

         ]
       ]
     ]
  ], [
     fhir:index 1;
     fhir:Observation.component.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a loinc:48642-3;
         fhir:Coding.system [ fhir:value "http://loinc.org" ];
         fhir:Coding.code [ fhir:value "48642-3" ];
         fhir:Coding.display [ fhir:value "Glomerular filtration rate/1.73 sq M predicted among non-blacks [Volume Rate/Area] in Serum or Plasma by Creatinine-based formula (MDRD)" ]
       ]
     ];
     fhir:Observation.component.valueQuantity [
       fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
     ];
     fhir:Observation.component.referenceRange [
       fhir:index 0;
       fhir:Observation.referenceRange.low [
         fhir:Quantity.value [ fhir:value "60"^^xsd:decimal ];
         fhir:Quantity.unit [ fhir:value "mL/min/1.73m2" ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "mL/min/{1.73_m2}" ]
       ];
       fhir:Observation.referenceRange.age [
         fhir:Range.low [
           fhir:Quantity.value [ fhir:value "18"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "yrs" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "a" ]

     ] )
  ] [
     fhir:code [
       fhir:coding ( [
         a loinc:48642-3 ;
         fhir:system [
           fhir:v "http://loinc.org"^^xsd:anyURI ;
           fhir:l <http://loinc.org>
         ] ;
         fhir:code [ fhir:v "48642-3" ] ;
         fhir:display [ fhir:v "GFR/BSA pr.non blk SerPlBld MDRD-ArV" ]
       ] ) #    Kind of observation = eGFR for non AA   
     ] ;
     fhir:value [
       a fhir:Quantity ;
       fhir:value [ fhir:v "60"^^xsd:decimal ] ; #    eGFR=54mL\/min\/1.73m2   
       fhir:unit [ fhir:v "mL/min/1.73m2" ] ;
       fhir:system [
         fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
         fhir:l <http://unitsofmeasure.org>
       ] ;
       fhir:code [ fhir:v "mL/min/{1.73_m2}" ]
     ] ;
     fhir:referenceRange ( [
       fhir:low [
         fhir:value [ fhir:v "60"^^xsd:decimal ] ;
         fhir:unit [ fhir:v "mL/min/1.73m2" ] ;
         fhir:system [
           fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
           fhir:l <http://unitsofmeasure.org>
         ] ;
         fhir:code [ fhir:v "mL/min/{1.73_m2}" ]
       ] ;
       fhir:age [
         fhir:low [
           fhir:value [ fhir:v "18"^^xsd:decimal ] ;
           fhir:unit [ fhir:v "yrs" ] ;
           fhir:system [
             fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ;
             fhir:l <http://unitsofmeasure.org>
           ] ;
           fhir:code [ fhir:v "a" ]

         ]
       ]
     ]
  ] .

     ] )
  ] ) . #    The MDRD equation does require race (African American or non-African American), which also might not be readily available. For this reason, eGFR values for both African Americans and non-African Americans are reported. so use component elements here  


<http://hl7.org/fhir/Patient/f201> a fhir:Patient .

<http://hl7.org/fhir/Practitioner/f202> a fhir:Practitioner .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/Observation/f205.ttl> a owl:Ontology;
  owl:imports fhir:fhir.ttl;
  owl:versionIRI <http://build.fhir.org/Observation/f205.ttl> .


# -------------------------------------------------------------------------------------

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.