Order for as needed (PRN) dosage - Vicodin - completed with dosageInstruction with additionalInstruction (coded) and as needed with reason, dispenseRequest and substitution

{
  "resourceType": "MedicationRequest",
  "id": "medrx0308",
  "text": {
    "status": "generated",
    "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: medrx0308</p><p><b>identifier</b>: 12345689 (OFFICIAL)</p><p><b>status</b>: completed</p><p><b>intent</b>: order</p><p><b>medication</b>: Vicodin 5/500 Oral Tablet <span>(Details : {RxNorm code '856907' = '856907', given as 'Vicodin 5/500 Oral Tablet'})</span></p><p><b>subject</b>: <a>Donald Duck</a></p><p><b>context</b>: <a>encounter who leads to this prescription</a></p><p><b>authoredOn</b>: 15/01/2015</p><h3>Requesters</h3><table><tr><td>-</td><td><b>Agent</b></td><td><b>OnBehalfOf</b></td></tr><tr><td>*</td><td><a>Patrick Pump</a></td><td><a>Organization/f002</a></td></tr></table><p><b>recorder</b>: <a>Carla Espinoza</a></p><p><b>dosageInstruction</b>: </p><h3>DispenseRequests</h3><table><tr><td>-</td><td><b>ValidityPeriod</b></td><td><b>Quantity</b></td><td><b>ExpectedSupplyDuration</b></td></tr><tr><td>*</td><td>15/01/2015 --&gt; 15/01/2016</td><td>30 TAB<span> (Details: http://hl7.org/fhir/v3/orderableDrugForm code TAB = 'Tablet')</span></td><td>10 days<span> (Details: UCUM code d = 'd')</span></td></tr></table><h3>Substitutions</h3><table><tr><td>-</td><td><b>Allowed</b></td><td><b>Reason</b></td></tr><tr><td>*</td><td>false</td><td>formulary policy <span>(Details : {http://hl7.org/fhir/v3/ActReason code 'FP' = 'formulary policy', given as 'formulary policy'})</span></td></tr></table></div>"
  },
  "identifier": [
    {
      "use": "official",
      "system": "http://www.bmc.nl/portal/prescriptions",
      "value": "12345689"

  "resourceType" : "MedicationRequest",
  "id" : "medrx0308",
  "identifier" : [{
    "use" : "official",
    "system" : "http://www.bmc.nl/portal/prescriptions",
    "value" : "12345689"
  }],
  "status" : "completed",
  "intent" : "order",
  "medication" : {
    "concept" : {
      "coding" : [{
        "system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
        "code" : "856907",
        "display" : "Vicodin 5/500 (hydrocodone bitartrate / APAP) Oral Tablet"
      }]

    }
  ],
  "status": "completed",
  "intent": "order",
  "medicationCodeableConcept": {
    "coding": [
      {
        "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
        "code": "856907",
        "display": "Vicodin 5/500 Oral Tablet"
      }
    ]

  },
  "subject": {
    "reference": "Patient/pat1",
    "display": "Donald Duck"

  "subject" : {
    "reference" : "Patient/pat1",
    "display" : "Donald Duck"

  },
  "context": {
    "reference": "Encounter/f001",
    "display": "encounter who leads to this prescription"

  "encounter" : {
    "reference" : "Encounter/f001",
    "display" : "encounter who leads to this prescription"

  },
  "authoredOn": "2015-01-15",
  "requester": {
    "agent": {
      "reference": "Practitioner/f007",
      "display": "Patrick Pump"
    },
    "onBehalfOf": {
      "reference": "Organization/f002"
    }

  "authoredOn" : "2015-01-15",
  "requester" : {
    "reference" : "Practitioner/f007",
    "display" : "Patrick Pump"

  },
  "recorder": {
    "reference": "Practitioner/f204",
    "display": "Carla Espinoza"

  "recorder" : {
    "reference" : "Practitioner/f204",
    "display" : "Carla Espinoza"

  },
  "dosageInstruction": [
    {
      "sequence": 1,
      "text": "1 tablet every four hours as needed for pain",
      "additionalInstruction": [
        {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "418914006",
              "display": "Warning. May cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink (qualifier value)"
            }
          ]
        }
      ],
      "timing": {
        "repeat": {
          "frequency": 1,
          "period": 4,
          "periodUnit": "h"

  "dosageInstruction" : {
    "simple" : {
      "text" : "1 tablet every four hours as needed for pain",
      "additionalInstruction" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "418914006",
          "display" : "Warning. May cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink (qualifier value)"
        }]
      }],
      "timing" : {
        "repeat" : {
          "frequency" : 1,
          "period" : 4,
          "periodUnit" : "h"

        }
      },
      "asNeededCodeableConcept": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "203082005",
            "display": "Fibromyalgia (disorder)"
          }
        ]
      },
      "route": {
        "coding": [
          {
            "system": "http://snomed.info/sct",
            "code": "26643006",
            "display": "Oral Route"
          }
        ]

      "asNeededFor" : [{
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "203082005",
          "display" : "Fibromyalgia (disorder)"
        }]
      }],
      "route" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "26643006",
          "display" : "Oral Route"
        }]

      },
      "doseQuantity": {
        "value": 1,
        "unit": "TAB",
        "system": "http://hl7.org/fhir/v3/orderableDrugForm",
        "code": "TAB"
      }

      "doseAndRate" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
            "code" : "ordered",
            "display" : "Ordered"
          }]
        },
        "doseQuantity" : {
          "value" : 1,
          "unit" : "TAB",
          "system" : "http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm",
          "code" : "TAB"
        }
      }]

    }
  ],
  "dispenseRequest": {
    "validityPeriod": {
      "start": "2015-01-15",
      "end": "2016-01-15"

  },
  "dispenseRequest" : {
    "validityPeriod" : {
      "start" : "2015-01-15",
      "end" : "2016-01-15"

    },
    "quantity": {
      "value": 30,
      "unit": "TAB",
      "system": "http://hl7.org/fhir/v3/orderableDrugForm",
      "code": "TAB"

    "quantity" : {
      "value" : 30,
      "unit" : "TAB",
      "system" : "http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm",
      "code" : "TAB"

    },
    "expectedSupplyDuration": {
      "value": 10,
      "unit": "days",
      "system": "http://unitsofmeasure.org",
      "code": "d"

    "expectedSupplyDuration" : {
      "value" : 10,
      "unit" : "days",
      "system" : "http://unitsofmeasure.org",
      "code" : "d"

    }
  },
  "substitution": {
    "allowed": false,
    "reason": {
      "coding": [
        {
          "system": "http://hl7.org/fhir/v3/ActReason",
          "code": "FP",
          "display": "formulary policy"
        }
      ]

  "substitution" : {
    "allowedBoolean" : false,
    "reason" : {
      "coding" : [{
        "system" : "http://terminology.hl7.org/CodeSystem/v3-ActReason",
        "code" : "FP",
        "display" : "formulary policy"
      }]

    }
  }
}