Dispense for Intravenous Chemotherapy (inpatient order) - Alemtuzumab (RxNorm Code) - completed with multiple dosageInstruction lines (id = "meddisp0306")

<?xml version="1.0" encoding="UTF-8"?>

<MedicationDispense xmlns="http://hl7.org/fhir">
  <id value="meddisp0306"/> 
  <contained> 
    <Medication> 
      <id value="med0303"/> 
      <code> 
        <coding> 
          <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/> 
          <code value="1594660"/> 
          <display value="alemtuzumab 10 MG/ML [Lemtrada]"/> 
        </coding> 
      </code> 
    </Medication> 
  </contained> 
  <status value="in-progress"/> 
  <medication> 
    <reference> 
      <!--   Linked to a RESOURCE Medication   -->
      <reference value="#med0303"/> 
      <display value="alemtuzumab 10 MG/ML [Lemtrada]"/> 
    </reference> 
  </medication> 
  <subject> 
    <reference value="Patient/pat1"/> 
    <display value="Donald Duck"/> 
  </subject> 
  <performer> 
    <actor> 
      <reference value="Practitioner/f006"/> 
    </actor> 
  </performer> 
  <authorizingPrescription> 
    <reference value="MedicationRequest/medrx0317"/> 
  </authorizingPrescription> 
  <type> 
    <coding> 
      <system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/> 
      <code value="DF"/> 
      <display value="Daily Fill"/> 
    </coding> 
  </type> 
  <quantity> 
    <value value="5"/> 
    <system value="http://snomed.info/sct"/> 
    <code value="415818006"/> 
  </quantity> 
  <daysSupply> 
    <value value="7"/> 
    <unit value="Day"/> 
    <system value="http://unitsofmeasure.org"/> 
    <code value="d"/> 
  </daysSupply> 
  <whenPrepared value="2015-01-15T10:20:00Z"/> 
  <dosageInstruction> 
    
    Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to
     the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate
     days for up to 12 wk
    
      
    
    
      
    
    
      
        
        
        
        
        
      
    
    
      
        
        
        
      
    
    
      
        
        
        
      
    
    
      
        
          
          
          
        
      
      
        
        
        
        
      
    
  
  
    
    Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to
     the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate
     days for up to 12 wk
    
      
    
    
      
    
    
      
        
        
        
        
        
      
    
    
      
        
        
        
      
    
    
      
        
        
        
      
    
    
      
        
          
          
          
        
      
      
        
        
        
        
      
    
  
  
    
    Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to
     the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate
     days for up to 12 wk
    
      
    
    
      
    
    
      
        
        
        
        
        
      
    
    
      
        
        
        
      
    
    
      
        
        
        
      
    
    
      
        
          
          
          
        
      
      
        
        
        
        
      
    

    <step> 
      <component> 
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to
         the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate
         days for up to 12 wk"/> 
        <additionalInstruction>           <text value="Rapidly increase dose until tolerated"/>         </additionalInstruction>         <additionalInstruction>           <text value="Administer on alternate days"/>         </additionalInstruction>         <timing>           <repeat>             <duration value="12"/>             <durationUnit value="wk"/>             <frequency value="3"/>             <period value="1"/>             <periodUnit value="wk"/>           </repeat>         </timing>         <route>           <coding>             <system value="http://snomed.info/sct"/>             <code value="47625008"/>             <display value="Intravenous route"/>           </coding>         </route>         <method>           <coding>             <system value="http://snomed.info/sct"/>             <code value="422145002"/>             <display value="Inject - dosing instruction imperative (qualifier value)"/>           </coding>         </method>         <doseAndRate>           <type>             <coding>               <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>               <code value="calculated"/>               <display value="Calculated"/>             </coding>           </type>           <doseQuantity>             <value value="3"/>             <unit value="mg"/>             <system value="http://unitsofmeasure.org"/>             <code value="mg"/>           </doseQuantity>         </doseAndRate>       </component>     </step>     <step>       <component>         <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to

         the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate
         days for up to 12 wk"/> 
        <additionalInstruction>           <text value="Rapidly increase dose until tolerated"/>         </additionalInstruction>         <additionalInstruction>           <text value="Administer on alternate days"/>         </additionalInstruction>         <timing>           <repeat>             <duration value="12"/>             <durationUnit value="wk"/>             <frequency value="3"/>             <period value="1"/>             <periodUnit value="wk"/>           </repeat>         </timing>         <route>           <coding>             <system value="http://snomed.info/sct"/>             <code value="47625008"/>             <display value="Intravenous route"/>           </coding>         </route>         <method>           <coding>             <system value="http://snomed.info/sct"/>             <code value="422145002"/>             <display value="Inject - dosing instruction imperative (qualifier value)"/>           </coding>         </method>         <doseAndRate>           <type>             <coding>               <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>               <code value="calculated"/>               <display value="Calculated"/>             </coding>           </type>           <doseQuantity>             <value value="10"/>             <unit value="mg"/>             <system value="http://unitsofmeasure.org"/>             <code value="mg"/>           </doseQuantity>         </doseAndRate>       </component>     </step>     <step>       <component>         <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to

         the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate
         days for up to 12 wk"/> 
        <additionalInstruction>           <text value="Rapidly increase dose until tolerated"/>         </additionalInstruction>         <additionalInstruction>           <text value="Administer on alternate days"/>         </additionalInstruction>         <timing>           <repeat>             <duration value="12"/>             <durationUnit value="wk"/>             <frequency value="3"/>             <period value="1"/>             <periodUnit value="wk"/>           </repeat>         </timing>         <route>           <coding>             <system value="http://snomed.info/sct"/>             <code value="47625008"/>             <display value="Intravenous route"/>           </coding>         </route>         <method>           <coding>             <system value="http://snomed.info/sct"/>             <code value="422145002"/>             <display value="Inject - dosing instruction imperative (qualifier value)"/>           </coding>         </method>         <doseAndRate>           <type>             <coding>               <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>               <code value="calculated"/>               <display value="Calculated"/>             </coding>           </type>           <doseQuantity>             <value value="30"/>             <unit value="mg"/>             <system value="http://unitsofmeasure.org"/>             <code value="mg"/>           </doseQuantity>         </doseAndRate>       </component>     </step> 
  </dosageInstruction> 


</

MedicationDispense

>