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See the Directory of published versions . Page versions: R5 R4B R4 R3 R2

Allergyintolerance.profile.xml

Example StructureDefinition/AllergyIntolerance (XML)

Maturity Level : N/A
Responsible Owner: Patient Care Work Group Standards Status : Informative Compartments : Patient , Practitioner , RelatedPerson

Raw XML ( canonical form + also see XML Format Specification )

Jump past Narrative

StructureDefinition for allergyintolerance

<?xml version="1.0" encoding="UTF-8"?>


  
  
    
  
  
    
    
      
        
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            AABJRU5ErkJggg== 
            AllergyIntolerance : Risk of harmful or undesirable, physiological response which is unique
             to an individual and associated with exposure to a substance.
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
            padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold; color:
             black; background-color: #fff5e6
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxAllergy or Intolerance (generally: Risk of adverse reaction to a substance)
            
            + Rule: AllergyIntolerance.clinicalStatus SHALL be present if verificationStatus is not
               entered-in-error.
            
            + Rule: AllergyIntolerance.clinicalStatus SHALL NOT be present if verification Status
               is entered-in-error
            Elements defined in Ancestors: 
            The logical id of the resource, as used in the URL for the resource. Once assigned, this
             value never changes., 

<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="AllergyIntolerance"/> 
  <meta> 
    <lastUpdated value="2025-11-10T04:50:58.407+00:00"/> 
  </meta> 
  <text> 
    <status value="generated"/> 
    <div xmlns="http://www.w3.org/1999/xhtml">
      <table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align:
       top;">
        <tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align:

         top">
          <th class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom:
           3px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="The logical name of the element">Name</a>           </th>           <th class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom:
           3px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Information about the use of the element">Flags</a>           </th>           <th class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom:
           3px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Minimum and Maximum # of times the element can appear in the instance">Card.</a>           </th>           <th class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom:
           3px; width: 100px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Reference to the type of the element">Type</a>           </th>           <th class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; padding-top: 3px; padding-bottom:
           3px">
            <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Additional information about the element">Description &amp; Constraints</a>             <span style="float: right">              <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format">                <img alt="doco" src="data:(snipped in html view)" style="background-color: inherit"/>               </a>             </span>           </th>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg
          DsHd9/w4EQIOamFnaBgAA4MMKAACAKwNp30CqZFfFmwAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Resource"/>              <span title="AllergyIntolerance : Risk of harmful or undesirable physiological response which

             is specific to an individual and associated with exposure to a substance.">AllergyIntolerance</span> 
            <a name="AllergyIntolerance"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="versions.html#std-process" style="padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold;

             color: black; background-color: #fff5e6; padding-left: 3px; padding-right: 3px;
             border: 1px grey solid; font-weight: bold; color: black; background-color: #fff5e6" title="Standards Status = Trial Use">TU</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="domainresource.html">DomainResource</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Allergy or Intolerance (generally: Risk of adverse reaction to a substance)
            <br/>              <br/>  Elements defined in Ancestors:             <a href="resource.html#Resource" title="The logical id of the resource, as used in the URL for the resource. Once assigned,

             this value never changes.">id</a> , 

            <a href="resource.html#Resource" title="The metadata about the resource. This is content that is maintained by the infrastructure.
             Changes to the content might not always be associated with version changes to the resource., 
            A reference to a set of rules that were followed when the resource was constructed, and
             which must be understood when processing the content. Often, this is a reference to an
             implementation guide that defines the special rules along with other profiles etc., 
            , 
            A human-readable narrative that contains a summary of the resource and can be used to
             represent the content of the resource to a human. The narrative need not encode all the
             structured data, but is required to contain sufficient detail to make it &quot;clinically
             safe&quot; for a human to just read the narrative. Resource definitions may define what
             content should be represented in the narrative to ensure clinical safety., 
            These resources do not have an independent existence apart from the resource that contains
             them - they cannot be identified independently, and nor can they have their own independent
             transaction scope., 

             Changes to the content might not always be associated with version changes to the
             resource.">meta</a> , 
            <a href="resource.html#Resource" title="A reference to a set of rules that were followed when the resource was constructed,

             and which must be understood when processing the content. Often, this is a reference
             to an implementation guide that defines the special rules along with other profiles
             etc. For DomainResources, if more than one implicitRules policy applies, additional
             policies may be conveyed using the [additionalImplicitRules](https://build.fhir.org/ig/HL7/fh
            ir-extensions/StructureDefinition-additionalImplicitRules.html) extension.">implicitRules</a> , 
            <a href="resource.html#Resource" title="The base language in which the resource is written.">language</a> ,             <a href="domainresource.html#DomainResource" title="A human-readable narrative that contains a summary of the resource and can be used

             to represent the content of the resource to a human. The narrative need not encode
             all the structured data, but is required to contain sufficient detail to make it
             &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions
             may define what content should be represented in the narrative to ensure clinical
             safety.">text</a> , 
            <a href="domainresource.html#DomainResource" title="These resources do not have an independent existence apart from the resource that

             contains them - they cannot be identified independently, nor can they have their
             own independent transaction scope. This is allowed to be a Parameters resource
             if and only if it is referenced by a resource that provides context/meaning.">contained</a> , 

            <a href="domainresource.html#DomainResource" title="May be used to represent additional information that is not part of the basic definition
             of the resource. To make the use of extensions safe and manageable, there is a strict
             set of governance  applied to the definition and use of extensions. Though any implementer
             can define an extension, there is a set of requirements that SHALL be met as part of the
             definition of the extension., 

             of the resource. To make the use of extensions safe and managable, there is a strict
             set of governance applied to the definition and use of extensions. Though any implementer
             can define an extension, there is a set of requirements that SHALL be met as part
             of the definition of the extension.">extension</a> , 

            <a href="domainresource.html#DomainResource" title="May be used to represent additional information that is not part of the basic definition
             of the resource and that modifies the understanding of the element that contains it and/or
             the understanding of the containing element's descendants. Usually modifier elements provide
             negation or qualification. To make the use of extensions safe and manageable, there is
             a strict set of governance applied to the definition and use of extensions. Though any
             implementer is allowed to define an extension, there is a set of requirements that SHALL
             be met as part of the definition of the extension. Applications processing a resource
             are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
             (including cannot change the meaning of modifierExtension itself).
          
        

        
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             of the resource and that modifies the understanding of the element that contains
             it and/or the understanding of the containing element's descendants. Usually modifier
             elements provide negation or qualification. To make the use of extensions safe
             and managable, there is a strict set of governance applied to the definition and
             use of extensions. Though any implementer is allowed to define an extension, there
             is a set of requirements that SHALL be met as part of the definition of the extension.
             Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or
             DomainResource (including cannot change the meaning of modifierExtension itself).">modifierExtension</a> 
          </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

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            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>  
            <span title="AllergyIntolerance.identifier : Business identifiers assigned to this AllergyIntolerance
             by the performer or other systems which remain constant as the resource is updated and
             propagates from server to server.
            
          
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             (
            )
          
        

        
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            AllergyIntolerance.verificationStatus : Assertion about certainty associated with the
             propensity, or potential risk, of a reaction to the identified substance (including pharmaceutical
             product).
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            
            
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxunconfirmed | confirmed | refuted | entered-in-error
            
            Assertion about certainty associated with a propensity, or potential risk, of a reaction
             to the identified substance. (
            )
          
        

        
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KG
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          sPVYVAgIJrA/sAAAAASUVORK5CYII=)
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
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            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC
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            TRgwAAAABJRU5ErkJggg== 
            AllergyIntolerance.type : Identification of the underlying physiological mechanism for
             the reaction risk.
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxallergy | intolerance - Underlying mechanism (if known)
            
             (
            )
          
        

        
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iV
          BORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6
          EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
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            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC
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            TRgwAAAABJRU5ErkJggg== 
            
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxfood | medication | environment | biologic
            
             (
            )
            
          
        

        
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KG
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          sPVYVAgIJrA/sAAAAASUVORK5CYII=)
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            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
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            TRgwAAAABJRU5ErkJggg== 

             by the performer or other systems which remain constant as the resource is updated
             and propagates from server to server.">identifier</span> 
            <a name="AllergyIntolerance.identifier"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Identifier">Identifier</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">External ids for this item
            <br/>              <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.clinicalStatus : The clinical status of the allergy or intolerance.">clinicalStatus</span>             <a name="AllergyIntolerance.clinicalStatus"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="conformance-rules.html#isModifier" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is a modifier element">?!</a> 
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">active | inactive | resolved
            <br/>  Binding:             <a href="valueset-allergyintolerance-clinical.html">AllergyIntolerance Clinical Status Codes</a>  (            <a href="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value

             set.">Required</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.verificationStatus : Assertion about certainty associated with

             the propensity, or potential risk, of a reaction to the identified substance (including
             pharmaceutical product).  The verification status pertains to the allergy or intolerance,
             itself, not to any specific AllergyIntolerance attribute.">verificationStatus</span> 
            <a name="AllergyIntolerance.verificationStatus"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="conformance-rules.html#isModifier" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is a modifier element">?!</a> 
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">unconfirmed | presumed | confirmed | refuted | entered-in-error
            <br/>  Binding:             <a href="valueset-allergyintolerance-verification.html">AllergyIntolerance Verification Status</a>  (            <a href="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value

             set.">Required</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.type : Identification of the underlying physiological mechanism

             for the reaction risk.">type</span> 
            <a name="AllergyIntolerance.type"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">allergy | intolerance - Underlying mechanism (if known)
            <br/>  Binding:             <a href="valueset-allergy-intolerance-type.html">Allergy Intolerance Type</a>  (            <a href="terminologies.html#preferred" title="Instances are encouraged to draw from the specified codes for interoperability

             purposes but are not required to do so to be considered conformant.">Preferred</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/>              <span title="AllergyIntolerance.category : Category of the identified substance.">category</span>             <a name="AllergyIntolerance.category"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#code">code</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">food | medication | environment | biologic
            <br/>  Binding:             <a href="valueset-allergy-intolerance-category.html">Allergy Intolerance Category</a>  (            <a href="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value

             set.">Required</a> )
            <br/>              <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>  
            <span title="AllergyIntolerance.criticality : Estimate of the potential clinical harm, or seriousness,
             of the reaction to the identified substance.
            
          
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          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxlow | high | unable-to-assess
            
            Estimate of the potential clinical harm, or seriousness, of a reaction to an identified
             substance. (
            )
          
        

        
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            AllergyIntolerance.code : Code for an allergy or intolerance statement (either a positive
             or a negated/excluded statement).  This may be a code for a substance or pharmaceutical
             product that is considered to be responsible for the adverse reaction risk (e.g., &quot;Latex&quot;)
            , an allergy or intolerance condition (e.g., &quot;Latex allergy&quot;), or a negated/excluded
             code for a specific substance or class (e.g., &quot;No latex allergy&quot;) or a general
             or categorical negated statement (e.g.,  &quot;No known allergy&quot;, &quot;No known
             drug allergies&quot;).  Note: the substance for a specific reaction may be different from
             the substance identified as the cause of the risk, but it must be consistent with it.
             For instance, it may be a more specific substance (e.g. a brand medication) or a composite
             product that includes the identified substance. It must be clinically safe to only process
             the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm
             that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.cod
            e, then the receiving system should ignore AllergyIntolerance.reaction.substance.
            
          
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          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxCode that identifies the allergy or intolerance
            
            Type of the substance/product, allergy or intolerance condition, or negation/exclusion
             codes for reporting no known allergies. (
            Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.)
          
        

        
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           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            (
            )
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
        

        
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          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            (
            )
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
        

        
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            AllergyIntolerance.onset[x] : Estimated or actual date,  date-time, or age when allergy
             or intolerance was identified.
            
          
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           padding:0px 4px 0px 4px
        

        
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            A date, date-time or partial date (e.g. just year or year + month).  If hours and minutes
             are specified, a time zone SHALL be populated. The format is a union of the schema types
             gYear, gYearMonth, date and dateTime. Seconds must be provided due to schema type constraints
             but may be zero-filled and may be ignored.                 Dates SHALL be valid dates.
          
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          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
        

        
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            AllergyIntolerance.recordedDate : The recordedDate represents when this particular AllergyIntoleranc
            e record was created in the system, which is often a system-generated date.
            
          
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           padding:0px 4px 0px 4px
        

        
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             of the reaction to the identified substance.">criticality</span> 
            <a name="AllergyIntolerance.criticality"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#code">code</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">low | high | unable-to-assess
            <br/>  Binding:             <a href="valueset-allergy-intolerance-criticality.html">Allergy Intolerance Criticality</a>  (            <a href="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value

             set.">Required</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.code : Code for an allergy or intolerance statement (either

             a positive or a negated/excluded statement).  This may be a code for a substance
             or pharmaceutical product that is considered to be responsible for the adverse
             reaction risk (e.g., &quot;Latex&quot;), an allergy or intolerance condition (e.g.,
             &quot;Latex allergy&quot;), or a negated/excluded code for a specific substance
             or class (e.g., &quot;No latex allergy&quot;) or a general or categorical negated
             statement (e.g.,  &quot;No known allergy&quot;, &quot;No known drug allergies&quot;).
              Note: the substance for a specific reaction may be different from the substance
             identified as the cause of the risk, but it must be consistent with it. For instance,
             it may be a more specific substance (e.g. a brand medication) or a composite product
             that includes the identified substance. It must be clinically safe to only process
             the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable
             to confirm that AllergyIntolerance.reaction.substance falls within the semantic
             scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.
            reaction.substance.">code</span> 
            <a name="AllergyIntolerance.code"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Code that identifies the allergy or intolerance
            <br/>  Binding:             <a href="valueset-allergyintolerance-code.html">AllergyIntolerance Substance/Product, Condition and Negation Codes</a>  (            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value

             set.  The value set merely provides examples of the types of concepts intended
             to be included.">Example</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>              <span title="AllergyIntolerance.patient : The patient who has the allergy or intolerance.">patient</span>             <a name="AllergyIntolerance.patient"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">1..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (            <a href="patient.html">Patient</a> )          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Who the allergy or intolerance is for
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>              <span title="AllergyIntolerance.encounter : The encounter when the allergy or intolerance was

             asserted.">encounter</span> 
            <a name="AllergyIntolerance.encounter"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (            <a href="encounter.html">Encounter</a> )          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Encounter when the allergy or intolerance was asserted
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Choice of Types"/>              <span title="AllergyIntolerance.onset[x] : Estimated or actual date,  date-time, or age when

             allergy or intolerance was identified.">onset[x]</span> 
            <a name="AllergyIntolerance.onset_x_"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">When allergy or intolerance was identified
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA
          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/>              <span title="A date, date-time or partial date (e.g. just year or year + month).  If hours and

             minutes are specified, a UTC offset SHALL be populated. The format is a union of
             the schema types gYear, gYearMonth, date and dateTime. Seconds must be provided
             due to schema type constraints but may be zero-filled and may be ignored.     
                        Dates SHALL be valid dates.">onsetDateTime</span> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#dateTime">dateTime</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA
          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="A duration of time during which an organism (or a process) has existed.">onsetAge</span>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Age">Age</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA
          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>              <span title="A time period defined by a start and end date and optionally time.">onsetPeriod</span>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Period">Period</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMUlEQVR4Xu3LMQoAIBA
          Dwftr/v8GtdbqEAthAtMspJJUx9rYW8ftHwAA+NcRAAAAXplLq0BWj/rZigAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="A set of ordered Quantities defined by a low and high limit.">onsetRange</span>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Range">Range</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/>              <span title="A sequence of Unicode characters">onsetString</span>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#string">string</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
        </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>              <span title="AllergyIntolerance.recordedDate : The recordedDate represents when this particular

             AllergyIntolerance record was created in the system, which is often a system-generated
             date.">recordedDate</span> 
            <a name="AllergyIntolerance.recordedDate"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#dateTime">dateTime</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Date allergy or intolerance was first recorded
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>  
            <span title="AllergyIntolerance.recorder : Individual who recorded the record and takes responsibility
             for its content.
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            (
             | 
             | 
             | 
            )
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
        

        
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KG
          goAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgC
          sPVYVAgIJrA/sAAAAASUVORK5CYII=)
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            KlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC 
            AllergyIntolerance.asserter : The source of the information about the allergy that is
             recorded.
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            (
             | 
             | 
             | 
            )
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
        

        
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iV
          BORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6
          EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC
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            klEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4Ov
            TRgwAAAABJRU5ErkJggg== 
            AllergyIntolerance.lastOccurrence : Represents the date and/or time of the last known
             occurrence of a reaction event.
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
        

        
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            AllergyIntolerance.note : Additional narrative about the propensity for the Adverse Reaction,
             not captured in other fields.
            
          
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          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxAdditional text not captured in other fields
            
          
        

        
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            AllergyIntolerance.reaction : Details about each adverse reaction event linked to exposure
             to the identified substance.
            
          
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          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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           solid; padding:0px 4px 0px 4pxAdverse Reaction Events linked to exposure to substance
            
          
        

        
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            AllergyIntolerance.reaction.substance : Identification of the specific substance (or pharmaceutical
             product) considered to be responsible for the Adverse Reaction event. Note: the substance
             for a specific reaction may be different from the substance identified as the cause of
             the risk, but it must be consistent with it. For instance, it may be a more specific substance
             (e.g. a brand medication) or a composite product that includes the identified substance.
             It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.
              If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance
             falls within the semantic scope of AllergyIntolerance.code, then the receiving system
             should ignore AllergyIntolerance.reaction.substance.
            
          
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           padding:0px 4px 0px 4px
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           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxSpecific substance or pharmaceutical product considered to be responsible for event
            
             (
            Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.)
          
        

        
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            AllergyIntolerance.reaction.manifestation : Clinical symptoms and/or signs that are observed
             or associated with the adverse reaction event.
            
          
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           solid; padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxClinical symptoms/signs associated with the Event
            
            Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction
             Event. (
            Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.)
            
          
        

        
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            AllergyIntolerance.reaction.description : Text description about the reaction as a whole,
             including details of the manifestation if required.
            
          
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           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
        

        
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           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iV
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            AllergyIntolerance.reaction.onset : Record of the date and/or time of the onset of the
             Reaction.
            
          
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           solid; padding:0px 4px 0px 4px
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          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
        

        
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           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KG
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            3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiY
            FCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAR
            klEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4Ov
            TRgwAAAABJRU5ErkJggg== 
            AllergyIntolerance.reaction.severity : Clinical assessment of the severity of the reaction
             event as a whole, potentially considering multiple different manifestations.
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxmild | moderate | severe (of event as a whole)
            
            Clinical assessment of the severity of a reaction event as a whole, potentially considering
             multiple different manifestations. (
            )
          
        

        
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iV
          BORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR42u3QwQkAMAwDsezq/WdIO4XJQwa9DTdJpulv258AAMANIgA
          AADUPYAVAgAJ//usAAAAASUVORK5CYII=)
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiY
            FCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC
            data: image/png;base64,R0lGODlhEAAQAPZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hY
            wbdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iS
            FVResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7 
            AllergyIntolerance.reaction.exposureRoute : Identification of the route by which the subject
             was exposed to the substance.
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4pxHow the subject was exposed to the substance
            
            A coded concept describing the route or physiological path of administration of a therapeutic
             agent into or onto the body of a subject. (
            Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.)
          
        

        
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KG
          goAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAA
          AASUVORK5CYII=)
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiY
            FCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=
            data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
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            L+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC
            data: image/png;base64,R0lGODlhEAAQAPZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///wD/ACH5BAEKAH8ALAAAAAAQABAAAAemgH+CgxeFF4OIhBdKGwFChYl/hY
            wbdkoBPnaQkosbG3d3VEpSUlonUoY1Gzo6QkI8SrGxWBOFG4uySgY5ZWR3PFy2hnaWZXC/PHcPwkpJk1ShoHcxhQEXSUmtFy6+0iS
            FVResrjoTPDzdcoU+F65CduVU6KAhhQa3F8Tx8nchBoYuqoTLZoAKFRIhqGwqJAULFx0GYpBQeChRIR4TJm6KJMhQRUSBAAA7 
            AllergyIntolerance.reaction.note : Additional text about the adverse reaction event not
             captured in other fields.
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px
            
          
          vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4pxText about event not captured in other fields
            
          
        

        
          
            
            
               Documentation for this format
            
          
        
      
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
    
  
  
  
  
  
  
  
  
    
      
      
    
  
  
    
      
      
    
  

             for accurately recording its content.">recorder</span> 
            <a name="AllergyIntolerance.recorder"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (            <a href="practitioner.html">Practitioner</a>  |             <a href="practitionerrole.html">PractitionerRole</a>  |             <a href="patient.html">Patient</a>  |             <a href="relatedperson.html">RelatedPerson</a>  |             <a href="organization.html">Organization</a> )          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Who recorded the sensitivity
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Reference to another Resource"/>              <span title="AllergyIntolerance.asserter : The source of the information about the allergy that

             is recorded.">asserter</span> 
            <a name="AllergyIntolerance.asserter"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null; padding-left: 3px; padding-right:

             3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#Reference">Reference</a> (            <a href="patient.html">Patient</a>  |             <a href="relatedperson.html">RelatedPerson</a>  |             <a href="practitioner.html">Practitioner</a>  |             <a href="practitionerrole.html">PractitionerRole</a> )          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Source of the information about the allergy
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/>              <span title="AllergyIntolerance.lastReactionOccurrence : Represents the date and/or time of

             the last known occurrence of a reaction event.">lastReactionOccurrence</span> 
            <a name="AllergyIntolerance.lastReactionOccurrence"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#dateTime">dateTime</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Date(/time) of last known occurrence of a reaction
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALUlEQVR4Xu3IoREAIAw
          EwfT6/ddA0GBAxO3NrLlKUj9263wAAAAvrgEAADClAVWFQIBRHMicAAAAAElFTkSuQmCC)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.note : Additional narrative about the propensity for the Adverse

             Reaction, not captured in other fields.">note</span> 
            <a name="AllergyIntolerance.note"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Annotation">Annotation</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Additional text not captured in other fields
            <br/>              <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg
          DsHd9/w4EQIOamFnaBgAA4MMKAACAKwNp30CqZFfFmwAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Element"/>              <span title="AllergyIntolerance.reaction : Details about each adverse reaction event linked

             to exposure to the identified substance.">reaction</span> 
            <a name="AllergyIntolerance.reaction"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="types.html#BackBoneElement">BackboneElement</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Adverse Reaction Events linked to exposure to substance
            <br/>              <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAw
          Esez6+89AqKGGJj7JzVWS+mm3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.reaction.substance : Identification of the specific substance

             (or pharmaceutical product) considered to be responsible for the Adverse Reaction
             event. Note: the substance for a specific reaction may be different from the substance
             identified as the cause of the risk, but it must be consistent with it. For instance,
             it may be a more specific substance (e.g. a brand medication) or a composite product
             that includes the identified substance. It must be clinically safe to only process
             the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable
             to confirm that AllergyIntolerance.reaction.substance falls within the semantic
             scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.
            reaction.substance.">substance</span> 
            <a name="AllergyIntolerance.reaction.substance"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Specific substance or pharmaceutical product considered to be responsible for event
            <br/>  Binding:             <a href="valueset-substance-code.html">Substance Code</a>  (            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value

             set.  The value set merely provides examples of the types of concepts intended
             to be included.">Example</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAw
          Esez6+89AqKGGJj7JzVWS+mm3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource"/>              <span title="AllergyIntolerance.reaction.manifestation : Clinical symptoms and/or signs that

             are observed or associated with the adverse reaction event.">manifestation</span> 
            <a name="AllergyIntolerance.reaction.manifestation"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">1..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="references.html#CodeableReference">CodeableReference</a> (            <a href="observation.html">Observation</a> )          </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Clinical symptoms/signs associated with the Event
            <br/>  Binding:             <a href="valueset-clinical-findings.html">SNOMED CT Clinical Findings</a>  (            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value

             set.  The value set merely provides examples of the types of concepts intended
             to be included.">Example</a> )
            <br/>              <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAw
          Esez6+89AqKGGJj7JzVWS+mm3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>              <span title="AllergyIntolerance.reaction.description : Text description about the reaction as

             a whole, including details of the manifestation if required.">description</span> 
            <a name="AllergyIntolerance.reaction.description"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#string">string</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Description of the event as a whole
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAw
          Esez6+89AqKGGJj7JzVWS+mm3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/>              <span title="AllergyIntolerance.reaction.onset : Record of the date and/or time of the onset

             of the Reaction.">onset</span> 
            <a name="AllergyIntolerance.reaction.onset"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#dateTime">dateTime</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Date(/time) when manifestations showed
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAw
          Esez6+89AqKGGJj7JzVWS+mm3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>              <span title="AllergyIntolerance.reaction.severity : Clinical assessment of the severity of the

             reaction event as a whole, potentially considering multiple different manifestations.">severity</span> 
            <a name="AllergyIntolerance.reaction.severity"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#code">code</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">mild | moderate | severe (of event as a whole)
            <br/>  Binding:             <a href="valueset-reaction-event-severity.html">Allergy Intolerance Severity</a>  (            <a href="terminologies.html#required" title="To be conformant, the concept in this element SHALL be from the specified value

             set.">Required</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         #F7F7F7">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR4Xu3IsQ0AIAw
          Esez6+89AqKGGJj7JzVWS+mm3zgcAAMxwDQAAgFcaYAVAgNGLTjgAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: #F7F7F7; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.reaction.exposureRoute : Identification of the route by which

             the subject was exposed to the substance.">exposureRoute</span> 
            <a name="AllergyIntolerance.reaction.exposureRoute"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: #F7F7F7;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">How the subject was exposed to the substance
            <br/>  Binding:             <a href="valueset-route-codes.html">SNOMED CT Route Codes</a>  (            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value

             set.  The value set merely provides examples of the types of concepts intended
             to be included.">Example</a> )
            <br/>            </td>         </tr>         <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color:

         white">
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image:
           url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAJUlEQVR4Xu3IIQEAAAg
          DsHd9/w4EQIOamFnaBgAA4MMKAACAKwNp30CqZFfFmwAAAABJRU5ErkJggg==)">
            <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: inherit"/>             <img alt="." class="hierarchy" src="data:(snipped in html view)" style="background-color: white; background-color: inherit" title="Data Type"/>              <span title="AllergyIntolerance.reaction.note : Additional text about the adverse reaction event

             not captured in other fields.">note</span> 
            <a name="AllergyIntolerance.reaction.note"> </a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">0..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Annotation">Annotation</a>           </td>           <td class="hierarchy" style="vertical-align: top; text-align : var(--ig-left,left); background-color: white;

           border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px">Text about event not captured in other fields
            <br/>              <br/>            </td>         </tr>         <tr>           <td class="hierarchy" colspan="5">            <br/>              <a href="https://build.fhir.org/ig/FHIR/ig-guidance/readingIgs.html#table-views" title="Legend for this format">              <img alt="doco" src="data:(snipped in html view)" style="background-color: inherit"/>  Documentation for this format            </a>           </td>         </tr>       </table>     </div>   </text>   <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">    <valueCode value="trial-use"/>   </extension>   <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">    <valueCode value="pc"/>   </extension>   <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">    <valueInteger value="3"/>   </extension>   <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category">    <valueCode value="patient"/>   </extension>   <url value="http://hl7.org/fhir/StructureDefinition/AllergyIntolerance"/>   <version value="6.0.0-ballot3"/>   <name value="AllergyIntolerance"/>   <status value="draft"/>   <experimental value="false"/>   <date value="2025-11-10T04:50:58+00:00"/>   <publisher value="HL7 International / Patient Care"/>   <contact>     <telecom>       <system value="url"/>       <value value="http://www.hl7.org/Special/committees/fiwg"/>     </telecom>   </contact>   <contact>     <telecom>       <system value="url"/>       <value value="http://www.hl7.org/Special/committees/patientcare"/>     </telecom>   </contact> 
  <description value="Risk of harmful or undesirable, physiological response which is unique to an individual
   and associated with exposure to a substance.
  To record a clinical assessment of a propensity, or potential risk to an individual, of
   an adverse reaction upon future exposure to the specified substance, or class of substance.
  
  
    
    
    
  
  
    
    
    
  
  
    
    
    
  
  
  
  
  
  
  
    
      
      
      Risk of harmful or undesirable, physiological response which is unique to an individual
       and associated with exposure to a substance.
      Substances include, but are not limited to: a therapeutic substance administered correctly
       at an appropriate dosage for the individual; food; material derived from plants or animals;
       or venom from insect stings.
      
      
      
      
      
      
        
        
        
      
      
        
        
        
        verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-v
        erification' and code = 'entered-in-error').exists() or clinicalStatus.exists()
        
      
      
        
        
        
        verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-v
        erification' and code = 'entered-in-error').empty() or clinicalStatus.empty()
        
      
      
        
        
        
        
        
        
      
      
        
        
        If the resource is contained in another resource, it SHALL be referred to from elsewhere
         in the resource or SHALL refer to the containing resource
        contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonica
        l) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(refer
        ence = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(c
        anonical) = '#').exists()).not()).trace('unmatched', id).empty()
        not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:refere
        nce/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))
        
      
      
        
        
        If a resource is contained in another resource, it SHALL NOT have a meta.versionId or
         a meta.lastUpdated
        
        
        
      
      
        
        
        
        
        
        
      
      
        
          
        
        
          When a resource has no narrative, only systems that fully understand the data can display
           the resource to a human safely. Including a human readable representation in the resource
           makes for a much more robust eco-system and cheaper handling of resources by intermediary
           systems. Some ecosystems restrict distribution of resources to only those systems that
           do fully understand the resources, and as a consequence implementers may believe that
           the narrative is superfluous. However experience shows that such eco-systems often open
           up to new participants over time.
        
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
    
    
      
      
      The logical id of the resource, as used in the URL for the resource. Once assigned, this
       value never changes.
      The only time that a resource does not have an id is when it is being submitted to the
       server using a create operation.
      
      
      
        
        
        
      
    <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
       (j)  -->
      
        
          
        
        
      
      
      
    
    
      
      

   and associated with exposure to a substance."/> 
  <jurisdiction>     <coding>       <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>       <code value="001"/>       <display value="World"/>     </coding>   </jurisdiction>   <purpose value="To record a clinical assessment of a propensity, or potential risk to an individual,

   of an adverse reaction upon future exposure to the specified substance, or class
   of substance."/> 
  <fhirVersion value="6.0.0-ballot3"/>   <mapping>     <identity value="w5"/>     <uri value="http://hl7.org/fhir/fivews"/>     <name value="FiveWs Pattern Mapping"/>   </mapping>   <mapping>     <identity value="rim"/>     <uri value="http://hl7.org/v3"/>     <name value="RIM Mapping"/>   </mapping>   <mapping>     <identity value="v2"/>     <uri value="http://hl7.org/v2"/>     <name value="HL7 V2 Mapping"/>   </mapping>   <kind value="resource"/>   <abstract value="false"/>   <type value="AllergyIntolerance"/>   <baseDefinition value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>   <derivation value="specialization"/>   <snapshot>     <element id="AllergyIntolerance">      <path value="AllergyIntolerance"/>       <short value="Allergy or Intolerance (generally: Risk of adverse reaction to a substance)"/>       <definition value="Risk of harmful or undesirable physiological response which is specific to an individual

       and associated with exposure to a substance."/> 
      <comment value="Substances include, but are not limited to: a therapeutic substance administered

       correctly at an appropriate dosage for the individual; food; material derived from
       plants or animals; or venom from insect stings."/> 
      <alias value="Allergy"/>       <alias value="Intolerance"/>       <alias value="Adverse Reaction"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance"/>         <min value="0"/>         <max value="*"/>       </base>       <constraint>         <key value="dom-2"/>         <severity value="error"/>         <human value="If the resource is contained in another resource, it SHALL NOT contain nested Resources"/>         <expression value="contained.contained.empty()"/>         <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>       </constraint>       <constraint>         <key value="dom-3"/>         <severity value="error"/>         <human value="If the resource is contained in another resource, it SHALL be referred to from

         elsewhere in the resource or SHALL refer to the containing resource"/> 
        <expression value="contained.where((('#'+id.trace('id') in %resource.descendants().select(reference

         | as(uri))) or descendants().where(reference='#' | as(uri)='#').exists()).not()).trace('unmat
        ched', id).empty()"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>       </constraint>       <constraint>         <key value="dom-4"/>         <severity value="error"/>         <human value="If a resource is contained in another resource, it SHALL NOT have a meta.versionId

         or a meta.lastUpdated"/> 
        <expression value="contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()"/>         <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>       </constraint>       <constraint>         <key value="dom-5"/>         <severity value="error"/>         <human value="If a resource is contained in another resource, it SHALL NOT have a security label"/>         <expression value="contained.meta.security.empty()"/>         <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>       </constraint>       <constraint>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice">          <valueBoolean value="true"/>         </extension>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation">          <valueMarkdown value="When a resource has no narrative, only systems that fully understand the data can

           display the resource to a human safely. Including a human readable representation
           in the resource makes for a much more robust eco-system and cheaper handling of
           resources by intermediary systems. Some ecosystems restrict distribution of resources
           to only those systems that do fully understand the resources, and as a consequence
           implementers may believe that the narrative is superfluous. However experience
           shows that such eco-systems often open up to new participants over time."/> 
        </extension>         <key value="dom-6"/>         <severity value="warning"/>         <human value="A resource should have narrative for robust management"/>         <expression value="text.`div`.exists()"/>         <source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="Entity, Role, or Act,Observation[classCode=OBS, moodCode=EVN]"/>       </mapping>       <mapping>         <identity value="w5"/>         <map value="clinical.general"/>       </mapping>     </element>     <element id="AllergyIntolerance.id">      <path value="AllergyIntolerance.id"/>       <short value="Logical id of this artifact"/>       <definition value="The logical id of the resource, as used in the URL for the resource. Once assigned,

       this value never changes."/> 
      <comment value="Within the context of the FHIR RESTful interactions, the resource has an id except

       for cases like the create and conditional update. Otherwise, the use of the resouce
       id depends on the given use case."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="Resource.id"/>         <min value="0"/>         <max value="1"/>       </base>       <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

       magic (j)  -->
      <type>         <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">          <valueUrl value="string"/>         </extension>         <code value="http://hl7.org/fhirpath/System.String"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>     </element>     <element id="AllergyIntolerance.meta">      <path value="AllergyIntolerance.meta"/>       <short value="Metadata about the resource"/> 
      <definition value="The metadata about the resource. This is content that is maintained by the infrastructure.
       Changes to the content might not always be associated with version changes to the resource.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
    
    
      
      
      A reference to a set of rules that were followed when the resource was constructed, and
       which must be understood when processing the content. Often, this is a reference to an
       implementation guide that defines the special rules along with other profiles etc.
      Asserting this rule set restricts the content to be only understood by a limited set of
       trading partners. This inherently limits the usefulness of the data in the long term.
       However, the existing health eco-system is highly fractured, and not yet ready to define,
       collect, and exchange data in a generally computable sense. Wherever possible, implementers
       and/or specification writers should avoid using this element. Often, when used, the URL
       is a reference to an implementation guide that defines these special rules as part of
       it's narrative along with other profiles, value sets, etc.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      

       Changes to the content might not always be associated with version changes to the
       resource."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="Resource.meta"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="Meta"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>     </element>     <element id="AllergyIntolerance.implicitRules">      <path value="AllergyIntolerance.implicitRules"/>       <short value="A set of rules under which this content was created"/>       <definition value="A reference to a set of rules that were followed when the resource was constructed,

       and which must be understood when processing the content. Often, this is a reference
       to an implementation guide that defines the special rules along with other profiles
       etc. For DomainResources, if more than one implicitRules policy applies, additional
       policies may be conveyed using the [additionalImplicitRules](https://build.fhir.org/ig/HL7/fh
      ir-extensions/StructureDefinition-additionalImplicitRules.html) extension."/> 
      <comment value="Asserting this rule set restricts the content to be only understood by a limited

       set of trading partners. This inherently limits the usefulness of the data in the
       long term. However, the existing health eco-system is highly fractured, and not
       yet ready to define, collect, and exchange data in a generally computable sense.
       Wherever possible, implementers and/or specification writers should avoid using
       this element. Often, when used, the URL is a reference to an implementation guide
       that defines these special rules as part of its narrative along with other profiles,
       value sets, etc."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="Resource.implicitRules"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="uri"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="true"/> 
      <isModifierReason value="This element is labeled as a modifier because the implicit rules may provide additional
       knowledge about the resource that modifies it's meaning or interpretation
      
    
    
      
      
      
      Language is provided to support indexing and accessibility (typically, services such as
       text to speech use the language tag). The html language tag in the narrative applies 
       to the narrative. The language tag on the resource may be used to specify the language
       of other presentations generated from the data in the resource. Not all the content has
       to be in the base language. The Resource.language should not be assumed to apply to the
       narrative automatically. If a language is specified, it should it also be specified on
       the div element in the html (see rules in HTML5 for information about the relationship
       between xml:lang and the html lang attribute).
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
          
        
        
          
        
        
        
        
      
    
    
      
      
      A human-readable narrative that contains a summary of the resource and can be used to
       represent the content of the resource to a human. The narrative need not encode all the
       structured data, but is required to contain sufficient detail to make it &quot;clinically
       safe&quot; for a human to just read the narrative. Resource definitions may define what
       content should be represented in the narrative to ensure clinical safety.
      Contained resources do not have narrative. Resources that are not contained SHOULD have
       a narrative. In some cases, a resource may only have text with little or no additional
       discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary
       for data from legacy systems where information is captured as a &quot;text blob&quot;
       or where text is additionally entered raw or narrated and encoded information is added
       later.
      
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
    
    
      
      
      These resources do not have an independent existence apart from the resource that contains
       them - they cannot be identified independently, and nor can they have their own independent
       transaction scope.
      This should never be done when the content can be identified properly, as once identification
       is lost, it is extremely difficult (and context dependent) to restore it again. Contained
       resources may have profiles and tags In their meta elements, but SHALL NOT have security
       labels.
      
      
      
      
      
      
        
        
        
      
      
        
      
      
      
      
        
        
      
    
    
      
      

       knowledge about the resource that modifies its meaning or interpretation"/> 
      <isSummary value="true"/>     </element>     <element id="AllergyIntolerance.language">      <path value="AllergyIntolerance.language"/>       <short value="Language of the resource content"/>       <definition value="The base language in which the resource is written."/>       <comment value="Language is provided to support indexing and accessibility (typically, services

       such as text to speech use the language tag). The html language tag in the narrative
       applies  to the narrative. The language tag on the resource may be used to specify
       the language of other presentations generated from the data in the resource. Not
       all the content has to be in the base language. The Resource.language should not
       be assumed to apply to the narrative automatically. If a language is specified,
       it should it also be specified on the div element in the html (see rules in HTML5
       for information about the relationship between xml:lang and the html lang attribute)."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="Resource.language"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="code"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="Language"/>         </extension>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding">          <valueBoolean value="true"/>         </extension>         <strength value="required"/>         <description value="IETF language tag for a human language"/>         <valueSet value="http://hl7.org/fhir/ValueSet/all-languages|6.0.0-ballot3"/>         <additional>           <purpose value="starter"/>           <valueSet value="http://hl7.org/fhir/ValueSet/languages"/>         </additional>       </binding>     </element>     <element id="AllergyIntolerance.text">      <path value="AllergyIntolerance.text"/>       <short value="Text summary of the resource, for human interpretation"/>       <definition value="A human-readable narrative that contains a summary of the resource and can be used

       to represent the content of the resource to a human. The narrative need not encode
       all the structured data, but is required to contain sufficient detail to make it
       &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions
       may define what content should be represented in the narrative to ensure clinical
       safety."/> 
      <comment value="Contained resources do not have a narrative. Resources that are not contained SHOULD

       have a narrative. In some cases, a resource may only have text with little or no
       additional discrete data (as long as all minOccurs=1 elements are satisfied). 
       This may be necessary for data from legacy systems where information is captured
       as a &quot;text blob&quot; or where text is additionally entered raw or narrated
       and encoded information is added later."/> 
      <alias value="narrative"/>       <alias value="html"/>       <alias value="xhtml"/>       <alias value="display"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="DomainResource.text"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="Narrative"/>       </type>       <condition value="dom-6"/>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="Act.text?"/>       </mapping>     </element>     <element id="AllergyIntolerance.contained">      <path value="AllergyIntolerance.contained"/>       <short value="Contained, inline Resources"/>       <definition value="These resources do not have an independent existence apart from the resource that

       contains them - they cannot be identified independently, nor can they have their
       own independent transaction scope. This is allowed to be a Parameters resource
       if and only if it is referenced by a resource that provides context/meaning."/> 
      <comment value="This should never be done when the content can be identified properly, as once

       identification is lost, it is extremely difficult (and context dependent) to restore
       it again. Contained resources may have profiles and tags in their meta elements,
       but SHALL NOT have security labels. Contained resources may be a resource type
       defined in the FHIR specification, or an [additional resource](resource.html#additional)."/> 
      <alias value="inline resources"/>       <alias value="anonymous resources"/>       <alias value="contained resources"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="DomainResource.contained"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Resource"/>       </type>       <condition value="dom-2"/>       <condition value="dom-4"/>       <condition value="dom-3"/>       <condition value="dom-5"/>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="N/A"/>       </mapping>     </element>     <element id="AllergyIntolerance.extension">      <path value="AllergyIntolerance.extension"/>       <short value="Additional content defined by implementations"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the resource. To make the use of extensions safe and manageable, there is a strict
       set of governance  applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part of the
       definition of the extension.
      There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone.
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
    
    
      
      

       of the resource. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part
       of the definition of the extension."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application,

       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification
       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/>       <alias value="user content"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="DomainResource.extension"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Extension"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="N/A"/>       </mapping>     </element>     <element id="AllergyIntolerance.modifierExtension">      <path value="AllergyIntolerance.modifierExtension"/>       <short value="Extensions that cannot be ignored"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the resource and that modifies the understanding of the element that contains it and/or
       the understanding of the containing element's descendants. Usually modifier elements provide
       negation or qualification. To make the use of extensions safe and manageable, there is
       a strict set of governance applied to the definition and use of extensions. Though any
       implementer is allowed to define an extension, there is a set of requirements that SHALL
       be met as part of the definition of the extension. Applications processing a resource
       are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
       (including cannot change the meaning of modifierExtension itself).
      There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone.
      Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly
       distinguished from the vast majority of extensions which can be safely ignored.  This
       promotes interoperability by eliminating the need for implementers to prohibit the presence
       of extensions. For further information, see the [definition of modifier extensions](extensibility.ht
      ml#modifierExtension).
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
        
        
        
        
        
        
      
      
      Modifier extensions are expected to modify the meaning or interpretation of the resource
       that contains them
      
      
        
        
      
    
    
      
      
      Business identifiers assigned to this AllergyIntolerance by the performer or other systems
       which remain constant as the resource is updated and propagates from server to server.
      This is a business identifier, not a resource identifier (see [discussion](resource.html#identifiers
      )).  It is best practice for the identifier to only appear on a single resource instance,
       however business practices may occasionally dictate that multiple resource instances with
       the same identifier can exist - possibly even with different resource types.  For example,
       multiple Patient and a Person resource instance might share the same social insurance
       number.

       of the resource and that modifies the understanding of the element that contains
       it and/or the understanding of the containing element's descendants. Usually modifier
       elements provide negation or qualification. To make the use of extensions safe
       and managable, there is a strict set of governance applied to the definition and
       use of extensions. Though any implementer is allowed to define an extension, there
       is a set of requirements that SHALL be met as part of the definition of the extension.
       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or
       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application,

       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification
       to retain a core level of simplicity for everyone."/> 
      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be

       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition
       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/>       <alias value="user content"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="DomainResource.modifierExtension"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Extension"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="true"/>       <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the

       resource that contains them"/> 
      <isSummary value="true"/>       <mapping>         <identity value="rim"/>         <map value="N/A"/>       </mapping>     </element>     <element id="AllergyIntolerance.identifier">      <path value="AllergyIntolerance.identifier"/>       <short value="External ids for this item"/>       <definition value="Business identifiers assigned to this AllergyIntolerance by the performer or other

       systems which remain constant as the resource is updated and propagates from server
       to server."/> 
      <comment value="This is a business identifier, not a resource identifier (see [discussion](resource.html#iden

      tifiers)).  It is best practice for the identifier to only appear on a single resource
       instance, however business practices may occasionally dictate that multiple resource
       instances with the same identifier can exist - possibly even with different resource
       types.  For example, multiple Patient and a Person resource instance might share
       the same social insurance number."/> 

      <requirements value="Allows identification of the AllergyIntolerance as it is known by various participating
       systems and in a way that remains consistent across servers.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      Refer to [discussion](extensibility.html#Special-Case) if clincalStatus is missing data.
The data type is CodeableConcept because clinicalStatus has some clinical judgment involved,
       such that there might need to be more specificity than the required FHIR value set allows.
       For example, a SNOMED coding might allow for additional specificity.
      
      
      
        
        
        
      
      
        
      
      
      
      
        
        
        
        
        
        
      
      
      This element is labeled as a modifier because the status contains the codes inactive and
       resolved that mark the AllergyIntolerance as no longer active.
      
      
        
          
        
        
        
        
      
      
        
        
      
      
        
        Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;clinicalStatus&
        quot;, moodCode=EVN].value
      
    
    
      
      
      Assertion about certainty associated with the propensity, or potential risk, of a reaction
       to the identified substance (including pharmaceutical product).

       systems and in a way that remains consistent across servers."/> 
      <min value="0"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance.identifier"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Identifier"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.identifier"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-7"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="id"/>       </mapping>     </element>     <element id="AllergyIntolerance.clinicalStatus">      <path value="AllergyIntolerance.clinicalStatus"/>       <short value="active | inactive | resolved"/>       <definition value="The clinical status of the allergy or intolerance."/>       <comment value="AllergyIntolerance.clinicalStatus should be present if verificationStatus is not

       entered-in-error and the AllergyIntolerance.code isn't negated (No Known Allergy,
       No Drug Allergy, No Food Allergy, No Latex Allergy).
Refer to [discussion](extensibility.html#Special-Case) if clinicalStatus is missing
       data.
The data type is CodeableConcept because clinicalStatus has some clinical judgment
       involved, such that there might need to be more specificity than the required FHIR
       value set allows. For example, a SNOMED coding might allow for additional specificity."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.clinicalStatus"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="CodeableConcept"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="true"/>       <isModifierReason value="This element is labeled as a modifier because the status contains the codes inactive

       and resolved that mark the AllergyIntolerance as no longer active."/> 
      <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceClinicalStatus"/>         </extension>         <strength value="required"/>         <description value="The clinical status of the allergy or intolerance."/>         <valueSet value="http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.status"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;clinical

        Status&quot;, moodCode=EVN].value"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.verificationStatus">      <path value="AllergyIntolerance.verificationStatus"/>       <short value="unconfirmed | presumed | confirmed | refuted | entered-in-error"/>       <definition value="Assertion about certainty associated with the propensity, or potential risk, of

       a reaction to the identified substance (including pharmaceutical product).  The
       verification status pertains to the allergy or intolerance, itself, not to any
       specific AllergyIntolerance attribute."/> 

      <comment value="The data type is CodeableConcept because verificationStatus has some clinical judgment
       involved, such that there might need to be more specificity than the required FHIR value
       set allows. For example, a SNOMED coding might allow for additional specificity.
      
      
      
        
        
        
      
      
        
      
      
      
      
        
        
        
        
        
        
      
      
      This element is labeled as a modifier because the status contains the codes refuted and
       entered-in-error that mark the AllergyIntolerance as not currently valid.
      
      
        
          
        
        
        Assertion about certainty associated with a propensity, or potential risk, of a reaction
         to the identified substance.
        
      
      
        
        
      
      
        
        Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;verificationSta
        tus&quot;, moodCode=EVN].value
      
    
    
      
      
      
      Allergic (typically immune-mediated) reactions have been traditionally regarded as an
       indicator for potential escalation to significant future risk. Contemporary knowledge
       suggests that some reactions previously thought to be immune-mediated are, in fact, non-immune,
       but in some cases can still pose a life threatening risk. It is acknowledged that many
       clinicians might not be in a position to distinguish the mechanism of a particular reaction.
       Often the term &quot;allergy&quot; is used rather generically and may overlap with the
       use of &quot;intolerance&quot; - in practice the boundaries between these two concepts
       might not be well-defined or understood. This data element is included nevertheless, because
       many legacy systems have captured this attribute. Immunologic testing may provide supporting
       evidence for the basis of the reaction and the causative substance, but no tests are 100%
       sensitive or specific for sensitivity to a particular substance. If, as is commonly the
       case, it is unclear whether the reaction is due to an allergy or an intolerance, then
       the type element should be omitted from the resource.
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
        
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      This data element has been included because it is currently being captured in some clinical
       systems. This data can be derived from the substance where coding systems are used, and
       is effectively redundant in that situation.  When searching on category, consider the
       implications of AllergyIntolerance resources without a category.  For example, when searching
       on category = medication, medication allergies that don't have a category valued will
       not be returned.  Refer to [search](search.html) for more information on how to search
       category with a :missing modifier to get allergies that don't have a category.  Additionally,
       category should be used with caution because category can be subjective based on the sender.
      
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
        
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      Estimate of the potential clinical harm, or seriousness, of the reaction to the identified
       substance.
      The default criticality value for any propensity to an adverse reaction should be 'Low
       Risk', indicating at the very least a relative contraindication to deliberate or voluntary
       exposure to the substance. 'High Risk' is flagged if the clinician has identified a propensity
       for a more serious or potentially life-threatening reaction, such as anaphylaxis, and
       implies an absolute contraindication to deliberate or voluntary exposure to the substance.
       If this element is missing, the criticality is unknown (though it may be known elsewhere).
        Systems that capture a severity at the condition level are actually representing the
       concept of criticality whereas the severity documented at the reaction level is representing
       the true reaction severity.  Existing systems that are capturing both condition criticality
       and reaction severity may use the term &quot;severity&quot; to represent both.  Criticality
       is the worst it could be in the future (i.e. situation-agnostic) whereas severity is situation-depen
      dent.
      
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        

       involved, such that there might need to be more specificity than the required FHIR
       value set allows. For example, a SNOMED coding might allow for additional specificity."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.verificationStatus"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="CodeableConcept"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="true"/>       <isModifierReason value="This element is labeled as a modifier because the status contains the codes refuted

       and entered-in-error that mark the AllergyIntolerance as not currently valid."/> 
      <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceVerificationStatus"/>         </extension>         <strength value="required"/>         <description value="Assertion about certainty associated with a propensity, or potential risk, of a

         reaction to the identified substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/allergyintolerance-verification|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.status"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;verifica

        tionStatus&quot;, moodCode=EVN].value"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.type">      <path value="AllergyIntolerance.type"/>       <short value="allergy | intolerance - Underlying mechanism (if known)"/>       <definition value="Identification of the underlying physiological mechanism for the reaction risk."/>       <comment value="Allergic (typically immune-mediated) reactions have been traditionally regarded

       as an indicator for potential escalation to significant future risk. Contemporary
       knowledge suggests that some reactions previously thought to be immune-mediated
       are, in fact, non-immune, but in some cases can still pose a life threatening risk.
       It is acknowledged that many clinicians might not be in a position to distinguish
       the mechanism of a particular reaction. Often the term &quot;allergy&quot; is used
       rather generically and may overlap with the use of &quot;intolerance&quot; - in
       practice the boundaries between these two concepts might not be well-defined or
       understood. This data element is included nevertheless, because many legacy systems
       have captured this attribute. Immunologic testing may provide supporting evidence
       for the basis of the reaction and the causative substance, but no tests are 100%
       sensitive or specific for sensitivity to a particular substance. If, as is commonly
       the case, it is unclear whether the reaction is due to an allergy or an intolerance,
       then the type element should be omitted from the resource."/> 
      <alias value="Category"/>       <alias value="Class"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.type"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="CodeableConcept"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceType"/>         </extension>         <strength value="preferred"/>         <description value="Identification of the underlying physiological mechanism for a Reaction Risk."/>         <valueSet value="http://hl7.org/fhir/ValueSet/allergy-intolerance-type"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.class"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-9"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="code"/>       </mapping>     </element>     <element id="AllergyIntolerance.category">      <path value="AllergyIntolerance.category"/>       <short value="food | medication | environment | biologic"/>       <definition value="Category of the identified substance."/>       <comment value="This data element has been included because it is currently being captured in some

       clinical systems. This data can be derived from the substance where coding systems
       are used, and is effectively redundant in that situation.  When searching on category,
       consider the implications of AllergyIntolerance resources without a category. 
       For example, when searching on category = medication, medication allergies that
       don't have a category valued will not be returned.  Refer to [search](search.html)
       for more information on how to search category with a :missing modifier to get
       allergies that don't have a category.  Additionally, category should be used with
       caution because category can be subjective based on the sender."/> 
      <alias value="Category"/>       <alias value="Type"/>       <alias value="Reaction Type"/>       <alias value="Class"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance.category"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="code"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceCategory"/>         </extension>         <strength value="required"/>         <description value="Category of an identified substance associated with allergies or intolerances."/>         <valueSet value="http://hl7.org/fhir/ValueSet/allergy-intolerance-category|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.class"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="AL1-2"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="value &lt; IntoleranceValue (Agent)"/>       </mapping>     </element>     <element id="AllergyIntolerance.criticality">      <path value="AllergyIntolerance.criticality"/>       <short value="low | high | unable-to-assess"/>       <definition value="Estimate of the potential clinical harm, or seriousness, of the reaction to the

       identified substance."/> 
      <comment value="The default criticality value for any propensity to an adverse reaction should

       be 'Low Risk', indicating at the very least a relative contraindication to deliberate
       or voluntary exposure to the substance. 'High Risk' is flagged if the clinician
       has identified a propensity for a more serious or potentially life-threatening
       reaction, such as anaphylaxis, and implies an absolute contraindication to deliberate
       or voluntary exposure to the substance. If this element is missing, the criticality
       is unknown (though it may be known elsewhere).  Systems that capture a severity
       at the condition level are actually representing the concept of criticality whereas
       the severity documented at the reaction level is representing the true reaction
       severity.  Existing systems that are capturing both condition criticality and reaction
       severity may use the term &quot;severity&quot; to represent both.  Criticality
       is the worst it could be in the future (i.e. situation-agnostic) whereas severity
       is situation-dependent."/> 
      <alias value="Severity"/>       <alias value="Seriousness"/>       <alias value="Contra-indication"/>       <alias value="Risk"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.criticality"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="code"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceCriticality"/>         </extension>         <strength value="required"/> 
        <description value="Estimate of the potential clinical harm, or seriousness, of a reaction to an identified
         substance.
        
      
      
        
        
      
      
        
        
      
      
        
        inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value
         &lt;= SeverityObservation (Severity Level)]
      
    
    
      
      

         substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.grade"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="AL1-4"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV,

         value &lt;= SeverityObservation (Severity Level)]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.code">      <path value="AllergyIntolerance.code"/>       <short value="Code that identifies the allergy or intolerance"/> 
      <definition value="Code for an allergy or intolerance statement (either a positive or a negated/excluded
       statement).  This may be a code for a substance or pharmaceutical product that is considered
       to be responsible for the adverse reaction risk (e.g., &quot;Latex&quot;), an allergy
       or intolerance condition (e.g., &quot;Latex allergy&quot;), or a negated/excluded code
       for a specific substance or class (e.g., &quot;No latex allergy&quot;) or a general or
       categorical negated statement (e.g.,  &quot;No known allergy&quot;, &quot;No known drug
       allergies&quot;).  Note: the substance for a specific reaction may be different from the
       substance identified as the cause of the risk, but it must be consistent with it. For
       instance, it may be a more specific substance (e.g. a brand medication) or a composite
       product that includes the identified substance. It must be clinically safe to only process
       the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm
       that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.cod
      e, then the receiving system should ignore AllergyIntolerance.reaction.substance.
      It is strongly recommended that this element be populated using a terminology, where possible.
       For example, some terminologies used include RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10,
       UNII, and ATC. Plain text should only be used if there is no appropriate terminology available.
       Additional details can be specified in the text.

When a substance or product code is specified for the 'code' element, the &quot;default&quot;
       semantic context is that this is a positive statement of an allergy or intolerance (depending
       on the value of the 'type' element, if present) condition to the specified substance/product.
        In the corresponding SNOMED CT allergy model, the specified substance/product is the
       target (destination) of the &quot;Causative agent&quot; relationship.

The 'substanceExposureRisk' extension is available as a structured and more flexible alternative
       to the 'code' element for making positive or negative allergy or intolerance statements.
        This extension provides the capability to make &quot;no known allergy&quot; (or &quot;no
       risk of adverse reaction&quot;) statements regarding any coded substance/product (including
       cases when a pre-coordinated &quot;no allergy to x&quot; concept for that substance/product
       does not exist).  If the 'substanceExposureRisk' extension is present, the AllergyIntolerance.code
       element SHALL be omitted.
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        

       statement).  This may be a code for a substance or pharmaceutical product that
       is considered to be responsible for the adverse reaction risk (e.g., &quot;Latex&quot;),
       an allergy or intolerance condition (e.g., &quot;Latex allergy&quot;), or a negated/excluded
       code for a specific substance or class (e.g., &quot;No latex allergy&quot;) or
       a general or categorical negated statement (e.g.,  &quot;No known allergy&quot;,
       &quot;No known drug allergies&quot;).  Note: the substance for a specific reaction
       may be different from the substance identified as the cause of the risk, but it
       must be consistent with it. For instance, it may be a more specific substance (e.g.
       a brand medication) or a composite product that includes the identified substance.
       It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.
        If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance
       falls within the semantic scope of AllergyIntolerance.code, then the receiving
       system should ignore AllergyIntolerance.reaction.substance."/> 
      <comment value="It is strongly recommended that this element be populated using a terminology,

       where possible. For example, some terminologies used include RxNorm, SNOMED CT,
       DM+D, NDFRT, ICD-9, IDC-10, UNII, and ATC. Plain text should only be used if there
       is no appropriate terminology available. Additional details can be specified in
       the text.

When a substance or product code is specified for the 'code' element, the &quot;default&quot;
       semantic context is that this is a positive statement of an allergy or intolerance
       (depending on the value of the 'type' element, if present) condition to the specified
       substance/product.  In the corresponding SNOMED CT allergy model, the specified
       substance/product is the target (destination) of the &quot;Causative agent&quot;
       relationship.

The 'substanceExposureRisk' extension is available as a structured and more flexible
       alternative to the 'code' element for making positive or negative allergy or intolerance
       statements.  This extension provides the capability to make &quot;no known allergy&quot;
       (or &quot;no risk of adverse reaction&quot;) statements regarding any coded substance/product
       (including cases when a pre-coordinated &quot;no allergy to x&quot; concept for
       that substance/product does not exist).  If the 'substanceExposureRisk' extension
       is present, the AllergyIntolerance.code element SHALL be omitted."/> 
      <alias value="Code"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.code"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="CodeableConcept"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceCode"/>         </extension>         <strength value="example"/> 
        <description value="Type of the substance/product, allergy or intolerance condition, or negation/exclusion
         codes for reporting no known allergies.
        
      
      
        
        
      
      
        
        
      
      
        
        substance/product:

.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND,
         code &lt;= ExposureAgentEntityType]

negated/excluded substance/product:

.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT,
         determinerCode=KIND, code &lt;= ExposureAgentEntityType]

positive or negated/excluded condition/situation:

Observation.code=ASSERTION; Observation.value
      
    
    
      
      
      
      
      
      
      
        
        
        
      
      
        
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      
      
      
        
        
        
      
      
        
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
      
      
        
      
      
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
    
    
      
      
      The recordedDate represents when this particular AllergyIntolerance record was created
       in the system, which is often a system-generated date.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      
      
      
      
        
        
        
      
      
        
        
        
        
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      The recorder takes responsibility for the content, but can reference the source from where
       they got it.
      
      
      
      
      
        
        
        
      
      
        
        
        
        
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      This date may be replicated by one of the Onset of Reaction dates. Where a textual representation
       of the date of last occurrence is required e.g. 'In Childhood, '10 years ago' the Comment
       element should be used.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;= CommonClinicalObs
        ervationType, value &lt;= ObservationValue (Reaction Type)].effectiveTime
      
    
    
      
      
      Additional narrative about the propensity for the Adverse Reaction, not captured in other
       fields.

         codes for reporting no known allergies."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/allergyintolerance-code"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.what[x]"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="AL1-3 / IAM-3"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="substance/product:

.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND

        , code &lt;= ExposureAgentEntityType]

negated/excluded substance/product:

.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT,
         determinerCode=KIND, code &lt;= ExposureAgentEntityType]

positive or negated/excluded condition/situation:

Observation.code=ASSERTION; Observation.value"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.patient">      <path value="AllergyIntolerance.patient"/>       <short value="Who the allergy or intolerance is for"/>       <definition value="The patient who has the allergy or intolerance."/>       <alias value="Patient"/>       <min value="1"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.patient"/>         <min value="1"/>         <max value="1"/>       </base>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.subject"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="(PID-3)"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=SBJ].role[classCode=PAT]"/>       </mapping>     </element>     <element id="AllergyIntolerance.encounter">      <path value="AllergyIntolerance.encounter"/>       <short value="Encounter when the allergy or intolerance was asserted"/>       <definition value="The encounter when the allergy or intolerance was asserted."/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.encounter"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Encounter"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.context"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]"/>       </mapping>     </element>     <element id="AllergyIntolerance.onset[x]">      <path value="AllergyIntolerance.onset[x]"/>       <short value="When allergy or intolerance was identified"/>       <definition value="Estimated or actual date,  date-time, or age when allergy or intolerance was identified."/>       <comment value="Age is generally used when the patient reports an age at which the AllergyIntolerance

       was noted. Period is generally used to convey an imprecise onset that occurred
       within the time period.  Range is generally used to convey an imprecise age range
       (e.g. 4 to 6 years old)."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.onset[x]"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="dateTime"/>       </type>       <type>         <code value="Age"/>       </type>       <type>         <code value="Period"/>       </type>       <type>         <code value="Range"/>       </type>       <type>         <code value="string"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.init"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="effectiveTime.low"/>       </mapping>     </element>     <element id="AllergyIntolerance.recordedDate">      <path value="AllergyIntolerance.recordedDate"/>       <short value="Date allergy or intolerance was first recorded"/>       <definition value="The recordedDate represents when this particular AllergyIntolerance record was

       created in the system, which is often a system-generated date."/> 
      <comment value="When onset date is unknown, recordedDate can be used to establish if the allergy

       or intolerance was present on or before a given date.  If the recordedDate is known
       and provided by a sending system, it is preferred that the receiving system preserve
       that recordedDate value. If the recordedDate is not provided by the sending system,
       the receipt timestamp is sometimes used as the recordedDate."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.recordedDate"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="dateTime"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.recorded"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-13"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=AUT].time"/>       </mapping>     </element>     <element id="AllergyIntolerance.recorder">      <path value="AllergyIntolerance.recorder"/>       <short value="Who recorded the sensitivity"/>       <definition value="Individual who recorded the record and takes responsibility for accurately recording

       its content."/> 
      <comment value="Because the recorder takes responsibility for accurately recording information

       in the record, the recorder is the most recent author.  The recorder might or might
       not be the asserter.  By contrast, the recordedDate is when the allergy or intolerance
       was first recorded."/> 
      <alias value="Author"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.recorder"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Practitioner"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/PractitionerRole"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/RelatedPerson"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Organization"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.author"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=AUT].role"/>       </mapping>     </element>     <element id="AllergyIntolerance.asserter">      <path value="AllergyIntolerance.asserter"/>       <short value="Source of the information about the allergy"/>       <definition value="The source of the information about the allergy that is recorded."/>       <comment value="The recorder takes responsibility for the content, but can reference the source

       from where they got it."/> 
      <alias value="Source"/>       <alias value="Informant"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.asserter"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/RelatedPerson"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Practitioner"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/PractitionerRole"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.source"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-14 (if patient) / IAM-18 (if practitioner)"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=INF].role"/>       </mapping>     </element>     <element id="AllergyIntolerance.lastReactionOccurrence">      <path value="AllergyIntolerance.lastReactionOccurrence"/>       <short value="Date(/time) of last known occurrence of a reaction"/>       <definition value="Represents the date and/or time of the last known occurrence of a reaction event."/>       <comment value="This date may be replicated by one of the Onset of Reaction dates. Where a textual

       representation of the date of last occurrence is required e.g. 'In Childhood, '10
       years ago' the AllergyIntolerance.note element should be used."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.lastReactionOccurrence"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="dateTime"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;=

         CommonClinicalObservationType, value &lt;= ObservationValue (Reaction Type)].effectiveTime"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.note">      <path value="AllergyIntolerance.note"/>       <short value="Additional text not captured in other fields"/>       <definition value="Additional narrative about the propensity for the Adverse Reaction, not captured

       in other fields."/> 

      <comment value="For example: including reason for flagging a seriousness of 'High Risk'; and instructions
       related to future exposure or administration of the substance, such as administration
       within an Intensive Care Unit or under corticosteroid cover. The notes should be related
       to an allergy or intolerance as a condition in general and not related to any particular
       episode of it. For episode notes and descriptions, use AllergyIntolerance.event.description
       and  AllergyIntolerance.event.notes.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
    
    
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;= CommonClinicalObs
        ervationType, value &lt;= ObservationValue (Reaction Type)]
      
    
    
      
      
      
      Unique id for the element within a resource (for internal references). This may be any
       string value that does not contain spaces.
      
      
      
        
        
        
      
    <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
       (j)  -->
      
        
          
        
        
      
      
      
      
        
        
      
    
    
      
      

       within an Intensive Care Unit or under corticosteroid cover. The notes should be
       related to an allergy or intolerance as a condition in general and not related
       to any particular episode of it. For episode notes and descriptions, use AllergyIntolerance.e
      vent.description and  AllergyIntolerance.event.notes."/> 
      <min value="0"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance.note"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Annotation"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="subjectOf.observationEvent[code=&quot;annotation&quot;].value"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction">      <path value="AllergyIntolerance.reaction"/>       <short value="Adverse Reaction Events linked to exposure to substance"/>       <definition value="Details about each adverse reaction event linked to exposure to the identified

       substance."/> 
      <min value="0"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance.reaction"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="BackboneElement"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children or both"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;=

         CommonClinicalObservationType, value &lt;= ObservationValue (Reaction Type)]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.reaction.id">      <path value="AllergyIntolerance.reaction.id"/>       <representation value="xmlAttr"/>       <short value="Unique id for inter-element referencing"/>       <definition value="Unique id for the element within a resource (for internal references). This may

       be any string value that does not contain spaces."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="Element.id"/>         <min value="0"/>         <max value="1"/>       </base>       <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler

       magic (j)  -->
      <type>         <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">          <valueUrl value="string"/>         </extension>         <code value="http://hl7.org/fhirpath/System.String"/>       </type>       <condition value="ele-1"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="n/a"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.extension">      <path value="AllergyIntolerance.reaction.extension"/>       <short value="Additional content defined by implementations"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and manageable, there is a strict set
       of governance  applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part of the
       definition of the extension.
      There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone.
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
    
    
      
      

       of the element. To make the use of extensions safe and managable, there is a strict
       set of governance applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part
       of the definition of the extension."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application,

       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification
       to retain a core level of simplicity for everyone."/> 
      <alias value="extensions"/>       <alias value="user content"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="Element.extension"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Extension"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="n/a"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.modifierExtension">      <path value="AllergyIntolerance.reaction.modifierExtension"/>       <short value="Extensions that cannot be ignored even if unrecognized"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is contained
       and/or the understanding of the containing element's descendants. Usually modifier elements
       provide negation or qualification. To make the use of extensions safe and manageable,
       there is a strict set of governance applied to the definition and use of extensions. Though
       any implementer can define an extension, there is a set of requirements that SHALL be
       met as part of the definition of the extension. Applications processing a resource are
       required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
       (including cannot change the meaning of modifierExtension itself).
      There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone.
      Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly
       distinguished from the vast majority of extensions which can be safely ignored.  This
       promotes interoperability by eliminating the need for implementers to prohibit the presence
       of extensions. For further information, see the [definition of modifier extensions](extensibility.ht
      ml#modifierExtension).
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
        
        
        
        
        
        
      
      
      Modifier extensions are expected to modify the meaning or interpretation of the element
       that contains them
      
      
        
        
      
    
    
      
      
      Identification of the specific substance (or pharmaceutical product) considered to be
       responsible for the Adverse Reaction event. Note: the substance for a specific reaction
       may be different from the substance identified as the cause of the risk, but it must be
       consistent with it. For instance, it may be a more specific substance (e.g. a brand medication)
       or a composite product that includes the identified substance. It must be clinically safe
       to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system
       is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic
       scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reactio
      n.substance.
      Coding of the specific substance (or pharmaceutical product) with a terminology capable
       of triggering decision support should be used wherever possible.  The 'code' element allows
       for the use of a specific substance or pharmaceutical product, or a group or class of
       substances. In the case of an allergy or intolerance to a class of substances, (for example,
       &quot;penicillins&quot;), the 'reaction.substance' element could be used to code the specific
       substance that was identified as having caused the reaction (for example, &quot;amoxycillin&quot;).
       Duplication of the value in the 'code' and 'reaction.substance' elements is acceptable
       when a specific substance has been recorded in 'code'.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
        
        
      
      
        
        outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code &lt;= ExposureCode].participation[ty
        peCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code &lt;=
         ExposureAgentEntityType]
      
    
    
      
      
      Clinical symptoms and/or signs that are observed or associated with the adverse reaction
       event.
      Manifestation can be expressed as a single word, phrase or brief description. For example:
       nausea, rash or no reaction. It is preferable that manifestation should be coded with
       a terminology, where possible. The values entered here may be used to display on an application
       screen as part of a list of adverse reactions, as recommended in the UK NHS CUI guidelines.
        Terminologies commonly used include, but are not limited to, SNOMED CT or ICD10.
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
        Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction
         Event.
        
      
      
        
        
      
      
        
        
      
    
    
      
      

       of the element and that modifies the understanding of the element in which it is
       contained and/or the understanding of the containing element's descendants. Usually
       modifier elements provide negation or qualification. To make the use of extensions
       safe and managable, there is a strict set of governance applied to the definition
       and use of extensions. Though any implementer can define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension.
       Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or
       DomainResource (including cannot change the meaning of modifierExtension itself)."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application,

       project, or standard - regardless of the institution or jurisdiction that uses
       or defines the extensions.  The use of extensions is what allows the FHIR specification
       to retain a core level of simplicity for everyone."/> 
      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be

       clearly distinguished from the vast majority of extensions which can be safely
       ignored.  This promotes interoperability by eliminating the need for implementers
       to prohibit the presence of extensions. For further information, see the [definition
       of modifier extensions](extensibility.html#modifierExtension)."/> 
      <alias value="extensions"/>       <alias value="user content"/>       <alias value="modifiers"/>       <min value="0"/>       <max value="*"/>       <base>         <path value="BackboneElement.modifierExtension"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Extension"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <isModifier value="true"/>       <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the

       element that contains them"/> 
      <isSummary value="true"/>       <mapping>         <identity value="rim"/>         <map value="N/A"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.substance">      <path value="AllergyIntolerance.reaction.substance"/>       <short value="Specific substance or pharmaceutical product considered to be responsible for event"/>       <definition value="Identification of the specific substance (or pharmaceutical product) considered

       to be responsible for the Adverse Reaction event. Note: the substance for a specific
       reaction may be different from the substance identified as the cause of the risk,
       but it must be consistent with it. For instance, it may be a more specific substance
       (e.g. a brand medication) or a composite product that includes the identified substance.
       It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.
        If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance
       falls within the semantic scope of AllergyIntolerance.code, then the receiving
       system should ignore AllergyIntolerance.reaction.substance."/> 
      <comment value="Coding of the specific substance (or pharmaceutical product) with a terminology

       capable of triggering decision support should be used wherever possible.  The 'code'
       element allows for the use of a specific substance or pharmaceutical product, or
       a group or class of substances. In the case of an allergy or intolerance to a class
       of substances, (for example, &quot;penicillins&quot;), the 'reaction.substance'
       element could be used to code the specific substance that was identified as having
       caused the reaction (for example, &quot;amoxycillin&quot;). Duplication of the
       value in the 'code' and 'reaction.substance' elements is acceptable when a specific
       substance has been recorded in 'code'."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.reaction.substance"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="CodeableConcept"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="SubstanceCode"/>         </extension>         <strength value="example"/>         <description value="Codes defining the type of the substance (including pharmaceutical products)."/>         <valueSet value="http://hl7.org/fhir/ValueSet/substance-code"/>       </binding>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code &lt;= ExposureCode].participa

        tion[typeCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND,
         code &lt;= ExposureAgentEntityType]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.reaction.manifestation">      <path value="AllergyIntolerance.reaction.manifestation"/>       <short value="Clinical symptoms/signs associated with the Event"/>       <definition value="Clinical symptoms and/or signs that are observed or associated with the adverse

       reaction event."/> 
      <comment value="Manifestation can be expressed as a single word, phrase or brief description. For

       example: nausea, rash or no reaction. It is preferable that manifestation should
       be coded with a terminology, where possible. The values entered here may be used
       to display on an application screen as part of a list of adverse reactions, as
       recommended in the UK NHS CUI guidelines.  Terminologies commonly used include,
       but are not limited to, SNOMED CT or ICD10."/> 
      <alias value="Symptoms"/>       <alias value="Signs"/>       <min value="1"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance.reaction.manifestation"/>         <min value="1"/>         <max value="*"/>       </base>       <type>         <code value="CodeableReference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Observation"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="Manifestation"/>         </extension>         <strength value="example"/>         <description value="Clinical symptoms and/or signs that are observed or associated with an Adverse

         Reaction Event."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/clinical-findings"/>       </binding>       <mapping>         <identity value="v2"/>         <map value="AL1-5"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="code"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.description">      <path value="AllergyIntolerance.reaction.description"/>       <short value="Description of the event as a whole"/> 
      <definition value="Text description about the reaction as a whole, including details of the manifestation
       if required.
      Use the description to provide any details of a particular event of the occurred reaction
       such as circumstances, reaction specifics, what happened before/after. Information, related
       to the event, but not describing a particular care should be captured in the comment field.
       For example: at the age of four, the patient was given penicillin for strep throat and
       subsequently developed severe hives.
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
    
    
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
      
        
        
      
    
    
      
      
      Clinical assessment of the severity of the reaction event as a whole, potentially considering
       multiple different manifestations.

       if required."/> 
      <comment value="Use the description to provide any details of a particular event of the occurred

       reaction such as circumstances, reaction specifics, what happened before/after.
       Information, related to the event, but not describing a particular care should
       be captured in the note field. For example: at the age of four, the patient was
       given penicillin for strep throat and subsequently developed severe hives."/> 
      <alias value="Narrative"/>       <alias value="Text"/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.reaction.description"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="string"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="text"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.onset">      <path value="AllergyIntolerance.reaction.onset"/>       <short value="Date(/time) when manifestations showed"/>       <definition value="Record of the date and/or time of the onset of the Reaction."/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.reaction.onset"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="dateTime"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="v2"/>         <map value="AL1-6"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="effectiveTime.low"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.severity">      <path value="AllergyIntolerance.reaction.severity"/>       <short value="mild | moderate | severe (of event as a whole)"/>       <definition value="Clinical assessment of the severity of the reaction event as a whole, potentially

       considering multiple different manifestations."/> 

      <comment value="It is acknowledged that this assessment is very subjective. There may be some specific
       practice domains where objective scales have been applied. Objective scales can be included
       in this model as extensions.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
        Clinical assessment of the severity of a reaction event as a whole, potentially considering
         multiple different manifestations.
        
      
      
        
        inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value
         &lt;= SeverityObservation (Severity Level)]
      
    
    
      
      
      
      
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
          
        
        
        A coded concept describing the route or physiological path of administration of a therapeutic
         agent into or onto the body of a subject.
        
      
      
        
        
      
    
    
      
      
      
      Use this field to record information indirectly related to a particular event and not
       captured in the description. For example: Clinical records are no longer available, recorded
       based on information provided to the patient by her mother and her mother is deceased.
      
      
      
        
        
        
      
      
        
      
      
        
        
        
        
        
        
      
      
      
      
        
        
      
    
  
  
    
      
      
      Risk of harmful or undesirable, physiological response which is unique to an individual
       and associated with exposure to a substance.
      Substances include, but are not limited to: a therapeutic substance administered correctly
       at an appropriate dosage for the individual; food; material derived from plants or animals;
       or venom from insect stings.
      
      
      
      
      
      
        
        
        
        verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-v
        erification' and code = 'entered-in-error').exists() or clinicalStatus.exists()
        
      
      
        
        
        
        verificationStatus.coding.where(system = 'http://terminology.hl7.org/CodeSystem/allergyintolerance-v
        erification' and code = 'entered-in-error').empty() or clinicalStatus.empty()
        
      
      
        
        
      
    
    
      
      
      Business identifiers assigned to this AllergyIntolerance by the performer or other systems
       which remain constant as the resource is updated and propagates from server to server.
      This is a business identifier, not a resource identifier (see [discussion](resource.html#identifiers
      )).  It is best practice for the identifier to only appear on a single resource instance,
       however business practices may occasionally dictate that multiple resource instances with
       the same identifier can exist - possibly even with different resource types.  For example,
       multiple Patient and a Person resource instance might share the same social insurance
       number.

       practice domains where objective scales have been applied. Objective scales can
       be included in this model as extensions."/> 
      <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.reaction.severity"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="code"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceSeverity"/>         </extension>         <strength value="required"/>         <description value="Clinical assessment of the severity of a reaction event as a whole, potentially

         considering multiple different manifestations."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/reaction-event-severity|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="rim"/>         <map value="inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV,

         value &lt;= SeverityObservation (Severity Level)]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.reaction.exposureRoute">      <path value="AllergyIntolerance.reaction.exposureRoute"/>       <short value="How the subject was exposed to the substance"/>       <definition value="Identification of the route by which the subject was exposed to the substance."/>       <comment value="Coding of the route of exposure with a terminology should be used wherever possible."/>       <min value="0"/>       <max value="1"/>       <base>         <path value="AllergyIntolerance.reaction.exposureRoute"/>         <min value="0"/>         <max value="1"/>       </base>       <type>         <code value="CodeableConcept"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="RouteOfAdministration"/>         </extension>         <strength value="example"/>         <description value="A coded concept describing the route or physiological path of exposure to a substance."/>         <valueSet value="http://hl7.org/fhir/ValueSet/route-codes"/>       </binding>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code &lt;= ExposureCode].routeCode"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.note">      <path value="AllergyIntolerance.reaction.note"/>       <short value="Text about event not captured in other fields"/>       <definition value="Additional text about the adverse reaction event not captured in other fields."/>       <comment value="Use this field to record information indirectly related to a particular event and

       not captured in the description. For example: Clinical records are no longer available,
       recorded based on information provided to the patient by her mother and her mother
       is deceased."/> 
      <min value="0"/>       <max value="*"/>       <base>         <path value="AllergyIntolerance.reaction.note"/>         <min value="0"/>         <max value="*"/>       </base>       <type>         <code value="Annotation"/>       </type>       <constraint>         <key value="ele-1"/>         <severity value="error"/>         <human value="All FHIR elements must have a @value or children"/>         <expression value="hasValue() or (children().count() &gt; id.count())"/>         <source value="http://hl7.org/fhir/StructureDefinition/Element"/>       </constraint>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="subjectOf.observationEvent[code=&quot;annotation&quot;].value"/>       </mapping>     </element>   </snapshot>   <differential>     <element id="AllergyIntolerance">      <path value="AllergyIntolerance"/>       <short value="Allergy or Intolerance (generally: Risk of adverse reaction to a substance)"/>       <definition value="Risk of harmful or undesirable physiological response which is specific to an individual

       and associated with exposure to a substance."/> 
      <comment value="Substances include, but are not limited to: a therapeutic substance administered

       correctly at an appropriate dosage for the individual; food; material derived from
       plants or animals; or venom from insect stings."/> 
      <alias value="Allergy"/>       <alias value="Intolerance"/>       <alias value="Adverse Reaction"/>       <min value="0"/>       <max value="*"/>       <mustSupport value="false"/>       <isModifier value="false"/>       <mapping>         <identity value="w5"/>         <map value="clinical.general"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="Observation[classCode=OBS, moodCode=EVN]"/>       </mapping>     </element>     <element id="AllergyIntolerance.identifier">      <path value="AllergyIntolerance.identifier"/>       <short value="External ids for this item"/>       <definition value="Business identifiers assigned to this AllergyIntolerance by the performer or other

       systems which remain constant as the resource is updated and propagates from server
       to server."/> 
      <comment value="This is a business identifier, not a resource identifier (see [discussion](resource.html#iden

      tifiers)).  It is best practice for the identifier to only appear on a single resource
       instance, however business practices may occasionally dictate that multiple resource
       instances with the same identifier can exist - possibly even with different resource
       types.  For example, multiple Patient and a Person resource instance might share
       the same social insurance number."/> 

      <requirements value="Allows identification of the AllergyIntolerance as it is known by various participating
       systems and in a way that remains consistent across servers.
      
      
      
        
      
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      Refer to [discussion](extensibility.html#Special-Case) if clincalStatus is missing data.
The data type is CodeableConcept because clinicalStatus has some clinical judgment involved,
       such that there might need to be more specificity than the required FHIR value set allows.
       For example, a SNOMED coding might allow for additional specificity.
      
      
      
        
      
      
      
      
      This element is labeled as a modifier because the status contains the codes inactive and
       resolved that mark the AllergyIntolerance as no longer active.
      
      
        
          
        
        
        
        
      
      
        
        
      
      
        
        Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;clinicalStatus&
        quot;, moodCode=EVN].value
      
    
    
      
      
      Assertion about certainty associated with the propensity, or potential risk, of a reaction
       to the identified substance (including pharmaceutical product).

       systems and in a way that remains consistent across servers."/> 
      <min value="0"/>       <max value="*"/>       <type>         <code value="Identifier"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.identifier"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-7"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="id"/>       </mapping>     </element>     <element id="AllergyIntolerance.clinicalStatus">      <path value="AllergyIntolerance.clinicalStatus"/>       <short value="active | inactive | resolved"/>       <definition value="The clinical status of the allergy or intolerance."/>       <comment value="AllergyIntolerance.clinicalStatus should be present if verificationStatus is not

       entered-in-error and the AllergyIntolerance.code isn't negated (No Known Allergy,
       No Drug Allergy, No Food Allergy, No Latex Allergy).
Refer to [discussion](extensibility.html#Special-Case) if clinicalStatus is missing
       data.
The data type is CodeableConcept because clinicalStatus has some clinical judgment
       involved, such that there might need to be more specificity than the required FHIR
       value set allows. For example, a SNOMED coding might allow for additional specificity."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="CodeableConcept"/>       </type>       <mustSupport value="false"/>       <isModifier value="true"/>       <isModifierReason value="This element is labeled as a modifier because the status contains the codes inactive

       and resolved that mark the AllergyIntolerance as no longer active."/> 
      <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceClinicalStatus"/>         </extension>         <strength value="required"/>         <description value="The clinical status of the allergy or intolerance."/>         <valueSet value="http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.status"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;clinical

        Status&quot;, moodCode=EVN].value"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.verificationStatus">      <path value="AllergyIntolerance.verificationStatus"/>       <short value="unconfirmed | presumed | confirmed | refuted | entered-in-error"/>       <definition value="Assertion about certainty associated with the propensity, or potential risk, of

       a reaction to the identified substance (including pharmaceutical product).  The
       verification status pertains to the allergy or intolerance, itself, not to any
       specific AllergyIntolerance attribute."/> 

      <comment value="The data type is CodeableConcept because verificationStatus has some clinical judgment
       involved, such that there might need to be more specificity than the required FHIR value
       set allows. For example, a SNOMED coding might allow for additional specificity.
      
      
      
        
      
      
      
      
      This element is labeled as a modifier because the status contains the codes refuted and
       entered-in-error that mark the AllergyIntolerance as not currently valid.
      
      
        
          
        
        
        Assertion about certainty associated with a propensity, or potential risk, of a reaction
         to the identified substance.
        
      
      
        
        
      
      
        
        Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;verificationSta
        tus&quot;, moodCode=EVN].value
      
    
    
      
      
      
      Allergic (typically immune-mediated) reactions have been traditionally regarded as an
       indicator for potential escalation to significant future risk. Contemporary knowledge
       suggests that some reactions previously thought to be immune-mediated are, in fact, non-immune,
       but in some cases can still pose a life threatening risk. It is acknowledged that many
       clinicians might not be in a position to distinguish the mechanism of a particular reaction.
       Often the term &quot;allergy&quot; is used rather generically and may overlap with the
       use of &quot;intolerance&quot; - in practice the boundaries between these two concepts
       might not be well-defined or understood. This data element is included nevertheless, because
       many legacy systems have captured this attribute. Immunologic testing may provide supporting
       evidence for the basis of the reaction and the causative substance, but no tests are 100%
       sensitive or specific for sensitivity to a particular substance. If, as is commonly the
       case, it is unclear whether the reaction is due to an allergy or an intolerance, then
       the type element should be omitted from the resource.
      
      
      
      
      
        
      
      
      
        
          
        
        
        
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      This data element has been included because it is currently being captured in some clinical
       systems. This data can be derived from the substance where coding systems are used, and
       is effectively redundant in that situation.  When searching on category, consider the
       implications of AllergyIntolerance resources without a category.  For example, when searching
       on category = medication, medication allergies that don't have a category valued will
       not be returned.  Refer to [search](search.html) for more information on how to search
       category with a :missing modifier to get allergies that don't have a category.  Additionally,
       category should be used with caution because category can be subjective based on the sender.
      
      
      
      
      
      
      
        
      
      
      
        
          
        
        
        
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      Estimate of the potential clinical harm, or seriousness, of the reaction to the identified
       substance.
      The default criticality value for any propensity to an adverse reaction should be 'Low
       Risk', indicating at the very least a relative contraindication to deliberate or voluntary
       exposure to the substance. 'High Risk' is flagged if the clinician has identified a propensity
       for a more serious or potentially life-threatening reaction, such as anaphylaxis, and
       implies an absolute contraindication to deliberate or voluntary exposure to the substance.
       If this element is missing, the criticality is unknown (though it may be known elsewhere).
        Systems that capture a severity at the condition level are actually representing the
       concept of criticality whereas the severity documented at the reaction level is representing
       the true reaction severity.  Existing systems that are capturing both condition criticality
       and reaction severity may use the term &quot;severity&quot; to represent both.  Criticality
       is the worst it could be in the future (i.e. situation-agnostic) whereas severity is situation-depen
      dent.
      
      
      
      
      
      
      
        
      
      
      
        
          
        
        

       involved, such that there might need to be more specificity than the required FHIR
       value set allows. For example, a SNOMED coding might allow for additional specificity."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="CodeableConcept"/>       </type>       <mustSupport value="false"/>       <isModifier value="true"/>       <isModifierReason value="This element is labeled as a modifier because the status contains the codes refuted

       and entered-in-error that mark the AllergyIntolerance as not currently valid."/> 
      <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceVerificationStatus"/>         </extension>         <strength value="required"/>         <description value="Assertion about certainty associated with a propensity, or potential risk, of a

         reaction to the identified substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/allergyintolerance-verification|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.status"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="Observation ACT .inboundRelationship[typeCode=COMP].source[classCode=OBS, code=&quot;verifica

        tionStatus&quot;, moodCode=EVN].value"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.type">      <path value="AllergyIntolerance.type"/>       <short value="allergy | intolerance - Underlying mechanism (if known)"/>       <definition value="Identification of the underlying physiological mechanism for the reaction risk."/>       <comment value="Allergic (typically immune-mediated) reactions have been traditionally regarded

       as an indicator for potential escalation to significant future risk. Contemporary
       knowledge suggests that some reactions previously thought to be immune-mediated
       are, in fact, non-immune, but in some cases can still pose a life threatening risk.
       It is acknowledged that many clinicians might not be in a position to distinguish
       the mechanism of a particular reaction. Often the term &quot;allergy&quot; is used
       rather generically and may overlap with the use of &quot;intolerance&quot; - in
       practice the boundaries between these two concepts might not be well-defined or
       understood. This data element is included nevertheless, because many legacy systems
       have captured this attribute. Immunologic testing may provide supporting evidence
       for the basis of the reaction and the causative substance, but no tests are 100%
       sensitive or specific for sensitivity to a particular substance. If, as is commonly
       the case, it is unclear whether the reaction is due to an allergy or an intolerance,
       then the type element should be omitted from the resource."/> 
      <alias value="Category"/>       <alias value="Class"/>       <min value="0"/>       <max value="1"/>       <type>         <code value="CodeableConcept"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceType"/>         </extension>         <strength value="preferred"/>         <description value="Identification of the underlying physiological mechanism for a Reaction Risk."/>         <valueSet value="http://hl7.org/fhir/ValueSet/allergy-intolerance-type"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.class"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-9"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="code"/>       </mapping>     </element>     <element id="AllergyIntolerance.category">      <path value="AllergyIntolerance.category"/>       <short value="food | medication | environment | biologic"/>       <definition value="Category of the identified substance."/>       <comment value="This data element has been included because it is currently being captured in some

       clinical systems. This data can be derived from the substance where coding systems
       are used, and is effectively redundant in that situation.  When searching on category,
       consider the implications of AllergyIntolerance resources without a category. 
       For example, when searching on category = medication, medication allergies that
       don't have a category valued will not be returned.  Refer to [search](search.html)
       for more information on how to search category with a :missing modifier to get
       allergies that don't have a category.  Additionally, category should be used with
       caution because category can be subjective based on the sender."/> 
      <alias value="Category"/>       <alias value="Type"/>       <alias value="Reaction Type"/>       <alias value="Class"/>       <min value="0"/>       <max value="*"/>       <type>         <code value="code"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceCategory"/>         </extension>         <strength value="required"/>         <description value="Category of an identified substance associated with allergies or intolerances."/>         <valueSet value="http://hl7.org/fhir/ValueSet/allergy-intolerance-category|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.class"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="AL1-2"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="value &lt; IntoleranceValue (Agent)"/>       </mapping>     </element>     <element id="AllergyIntolerance.criticality">      <path value="AllergyIntolerance.criticality"/>       <short value="low | high | unable-to-assess"/>       <definition value="Estimate of the potential clinical harm, or seriousness, of the reaction to the

       identified substance."/> 
      <comment value="The default criticality value for any propensity to an adverse reaction should

       be 'Low Risk', indicating at the very least a relative contraindication to deliberate
       or voluntary exposure to the substance. 'High Risk' is flagged if the clinician
       has identified a propensity for a more serious or potentially life-threatening
       reaction, such as anaphylaxis, and implies an absolute contraindication to deliberate
       or voluntary exposure to the substance. If this element is missing, the criticality
       is unknown (though it may be known elsewhere).  Systems that capture a severity
       at the condition level are actually representing the concept of criticality whereas
       the severity documented at the reaction level is representing the true reaction
       severity.  Existing systems that are capturing both condition criticality and reaction
       severity may use the term &quot;severity&quot; to represent both.  Criticality
       is the worst it could be in the future (i.e. situation-agnostic) whereas severity
       is situation-dependent."/> 
      <alias value="Severity"/>       <alias value="Seriousness"/>       <alias value="Contra-indication"/>       <alias value="Risk"/>       <min value="0"/>       <max value="1"/>       <type>         <code value="code"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceCriticality"/>         </extension>         <strength value="required"/> 
        <description value="Estimate of the potential clinical harm, or seriousness, of a reaction to an identified
         substance.
        
      
      
        
        
      
      
        
        
      
      
        
        inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value
         &lt;= SeverityObservation (Severity Level)]
      
    
    
      
      

         substance."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.grade"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="AL1-4"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV,

         value &lt;= SeverityObservation (Severity Level)]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.code">      <path value="AllergyIntolerance.code"/>       <short value="Code that identifies the allergy or intolerance"/> 
      <definition value="Code for an allergy or intolerance statement (either a positive or a negated/excluded
       statement).  This may be a code for a substance or pharmaceutical product that is considered
       to be responsible for the adverse reaction risk (e.g., &quot;Latex&quot;), an allergy
       or intolerance condition (e.g., &quot;Latex allergy&quot;), or a negated/excluded code
       for a specific substance or class (e.g., &quot;No latex allergy&quot;) or a general or
       categorical negated statement (e.g.,  &quot;No known allergy&quot;, &quot;No known drug
       allergies&quot;).  Note: the substance for a specific reaction may be different from the
       substance identified as the cause of the risk, but it must be consistent with it. For
       instance, it may be a more specific substance (e.g. a brand medication) or a composite
       product that includes the identified substance. It must be clinically safe to only process
       the 'code' and ignore the 'reaction.substance'.  If a receiving system is unable to confirm
       that AllergyIntolerance.reaction.substance falls within the semantic scope of AllergyIntolerance.cod
      e, then the receiving system should ignore AllergyIntolerance.reaction.substance.
      It is strongly recommended that this element be populated using a terminology, where possible.
       For example, some terminologies used include RxNorm, SNOMED CT, DM+D, NDFRT, ICD-9, IDC-10,
       UNII, and ATC. Plain text should only be used if there is no appropriate terminology available.
       Additional details can be specified in the text.

When a substance or product code is specified for the 'code' element, the &quot;default&quot;
       semantic context is that this is a positive statement of an allergy or intolerance (depending
       on the value of the 'type' element, if present) condition to the specified substance/product.
        In the corresponding SNOMED CT allergy model, the specified substance/product is the
       target (destination) of the &quot;Causative agent&quot; relationship.

The 'substanceExposureRisk' extension is available as a structured and more flexible alternative
       to the 'code' element for making positive or negative allergy or intolerance statements.
        This extension provides the capability to make &quot;no known allergy&quot; (or &quot;no
       risk of adverse reaction&quot;) statements regarding any coded substance/product (including
       cases when a pre-coordinated &quot;no allergy to x&quot; concept for that substance/product
       does not exist).  If the 'substanceExposureRisk' extension is present, the AllergyIntolerance.code
       element SHALL be omitted.
      
      
      
      
        
      
      
      
        
          
        
        

       statement).  This may be a code for a substance or pharmaceutical product that
       is considered to be responsible for the adverse reaction risk (e.g., &quot;Latex&quot;),
       an allergy or intolerance condition (e.g., &quot;Latex allergy&quot;), or a negated/excluded
       code for a specific substance or class (e.g., &quot;No latex allergy&quot;) or
       a general or categorical negated statement (e.g.,  &quot;No known allergy&quot;,
       &quot;No known drug allergies&quot;).  Note: the substance for a specific reaction
       may be different from the substance identified as the cause of the risk, but it
       must be consistent with it. For instance, it may be a more specific substance (e.g.
       a brand medication) or a composite product that includes the identified substance.
       It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.
        If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance
       falls within the semantic scope of AllergyIntolerance.code, then the receiving
       system should ignore AllergyIntolerance.reaction.substance."/> 
      <comment value="It is strongly recommended that this element be populated using a terminology,

       where possible. For example, some terminologies used include RxNorm, SNOMED CT,
       DM+D, NDFRT, ICD-9, IDC-10, UNII, and ATC. Plain text should only be used if there
       is no appropriate terminology available. Additional details can be specified in
       the text.

When a substance or product code is specified for the 'code' element, the &quot;default&quot;
       semantic context is that this is a positive statement of an allergy or intolerance
       (depending on the value of the 'type' element, if present) condition to the specified
       substance/product.  In the corresponding SNOMED CT allergy model, the specified
       substance/product is the target (destination) of the &quot;Causative agent&quot;
       relationship.

The 'substanceExposureRisk' extension is available as a structured and more flexible
       alternative to the 'code' element for making positive or negative allergy or intolerance
       statements.  This extension provides the capability to make &quot;no known allergy&quot;
       (or &quot;no risk of adverse reaction&quot;) statements regarding any coded substance/product
       (including cases when a pre-coordinated &quot;no allergy to x&quot; concept for
       that substance/product does not exist).  If the 'substanceExposureRisk' extension
       is present, the AllergyIntolerance.code element SHALL be omitted."/> 
      <alias value="Code"/>       <min value="0"/>       <max value="1"/>       <type>         <code value="CodeableConcept"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceCode"/>         </extension>         <strength value="example"/> 
        <description value="Type of the substance/product, allergy or intolerance condition, or negation/exclusion
         codes for reporting no known allergies.
        
      
      
        
        
      
      
        
        
      
      
        
        substance/product:

.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND,
         code &lt;= ExposureAgentEntityType]

negated/excluded substance/product:

.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT,
         determinerCode=KIND, code &lt;= ExposureAgentEntityType]

positive or negated/excluded condition/situation:

Observation.code=ASSERTION; Observation.value
      
    
    
      
      
      
      
      
      
      
        
        
      
      
      
        
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      
      
      
        
      
      
        
      
      
        
      
      
        
      
      
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      The recordedDate represents when this particular AllergyIntolerance record was created
       in the system, which is often a system-generated date.
      
      
      
        
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      
      
      
      
        
        
        
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      The recorder takes responsibility for the content, but can reference the source from where
       they got it.
      
      
      
      
      
        
        
        
        
        
      
      
      
        
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      
      This date may be replicated by one of the Onset of Reaction dates. Where a textual representation
       of the date of last occurrence is required e.g. 'In Childhood, '10 years ago' the Comment
       element should be used.
      
      
      
        
      
      
        
        outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;= CommonClinicalObs
        ervationType, value &lt;= ObservationValue (Reaction Type)].effectiveTime
      
    
    
      
      
      Additional narrative about the propensity for the Adverse Reaction, not captured in other
       fields.

         codes for reporting no known allergies."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/allergyintolerance-code"/>       </binding>       <mapping>         <identity value="w5"/>         <map value="FiveWs.what[x]"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="AL1-3 / IAM-3"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="substance/product:

.participation[typeCode=CAGNT].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND

        , code &lt;= ExposureAgentEntityType]

negated/excluded substance/product:

.participation[typeCode=CAGNT, negationInd=true].role[classCode=ADMM].player[classCode=MAT,
         determinerCode=KIND, code &lt;= ExposureAgentEntityType]

positive or negated/excluded condition/situation:

Observation.code=ASSERTION; Observation.value"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.patient">      <path value="AllergyIntolerance.patient"/>       <short value="Who the allergy or intolerance is for"/>       <definition value="The patient who has the allergy or intolerance."/>       <alias value="Patient"/>       <min value="1"/>       <max value="1"/>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.subject"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="(PID-3)"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=SBJ].role[classCode=PAT]"/>       </mapping>     </element>     <element id="AllergyIntolerance.encounter">      <path value="AllergyIntolerance.encounter"/>       <short value="Encounter when the allergy or intolerance was asserted"/>       <definition value="The encounter when the allergy or intolerance was asserted."/>       <min value="0"/>       <max value="1"/>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Encounter"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.context"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]"/>       </mapping>     </element>     <element id="AllergyIntolerance.onset[x]">      <path value="AllergyIntolerance.onset[x]"/>       <short value="When allergy or intolerance was identified"/>       <definition value="Estimated or actual date,  date-time, or age when allergy or intolerance was identified."/>       <comment value="Age is generally used when the patient reports an age at which the AllergyIntolerance

       was noted. Period is generally used to convey an imprecise onset that occurred
       within the time period.  Range is generally used to convey an imprecise age range
       (e.g. 4 to 6 years old)."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="dateTime"/>       </type>       <type>         <code value="Age"/>       </type>       <type>         <code value="Period"/>       </type>       <type>         <code value="Range"/>       </type>       <type>         <code value="string"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.init"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="effectiveTime.low"/>       </mapping>     </element>     <element id="AllergyIntolerance.recordedDate">      <path value="AllergyIntolerance.recordedDate"/>       <short value="Date allergy or intolerance was first recorded"/>       <definition value="The recordedDate represents when this particular AllergyIntolerance record was

       created in the system, which is often a system-generated date."/> 
      <comment value="When onset date is unknown, recordedDate can be used to establish if the allergy

       or intolerance was present on or before a given date.  If the recordedDate is known
       and provided by a sending system, it is preferred that the receiving system preserve
       that recordedDate value. If the recordedDate is not provided by the sending system,
       the receipt timestamp is sometimes used as the recordedDate."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="dateTime"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.recorded"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-13"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=AUT].time"/>       </mapping>     </element>     <element id="AllergyIntolerance.recorder">      <path value="AllergyIntolerance.recorder"/>       <short value="Who recorded the sensitivity"/>       <definition value="Individual who recorded the record and takes responsibility for accurately recording

       its content."/> 
      <comment value="Because the recorder takes responsibility for accurately recording information

       in the record, the recorder is the most recent author.  The recorder might or might
       not be the asserter.  By contrast, the recordedDate is when the allergy or intolerance
       was first recorded."/> 
      <alias value="Author"/>       <min value="0"/>       <max value="1"/>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Practitioner"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/PractitionerRole"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/RelatedPerson"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Organization"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.author"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=AUT].role"/>       </mapping>     </element>     <element id="AllergyIntolerance.asserter">      <path value="AllergyIntolerance.asserter"/>       <short value="Source of the information about the allergy"/>       <definition value="The source of the information about the allergy that is recorded."/>       <comment value="The recorder takes responsibility for the content, but can reference the source

       from where they got it."/> 
      <alias value="Source"/>       <alias value="Informant"/>       <min value="0"/>       <max value="1"/>       <type>         <code value="Reference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/RelatedPerson"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Practitioner"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/PractitionerRole"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="true"/>       <mapping>         <identity value="w5"/>         <map value="FiveWs.source"/>       </mapping>       <mapping>         <identity value="v2"/>         <map value="IAM-14 (if patient) / IAM-18 (if practitioner)"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value=".participation[typeCode=INF].role"/>       </mapping>     </element>     <element id="AllergyIntolerance.lastReactionOccurrence">      <path value="AllergyIntolerance.lastReactionOccurrence"/>       <short value="Date(/time) of last known occurrence of a reaction"/>       <definition value="Represents the date and/or time of the last known occurrence of a reaction event."/>       <comment value="This date may be replicated by one of the Onset of Reaction dates. Where a textual

       representation of the date of last occurrence is required e.g. 'In Childhood, '10
       years ago' the AllergyIntolerance.note element should be used."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="dateTime"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;=

         CommonClinicalObservationType, value &lt;= ObservationValue (Reaction Type)].effectiveTime"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.note">      <path value="AllergyIntolerance.note"/>       <short value="Additional text not captured in other fields"/>       <definition value="Additional narrative about the propensity for the Adverse Reaction, not captured

       in other fields."/> 

      <comment value="For example: including reason for flagging a seriousness of 'High Risk'; and instructions
       related to future exposure or administration of the substance, such as administration
       within an Intensive Care Unit or under corticosteroid cover. The notes should be related
       to an allergy or intolerance as a condition in general and not related to any particular
       episode of it. For episode notes and descriptions, use AllergyIntolerance.event.description
       and  AllergyIntolerance.event.notes.
      
      
      
        
      
      
        
        
      
    
    
      
      
      
      
      
      
        
      
      
        
        outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;= CommonClinicalObs
        ervationType, value &lt;= ObservationValue (Reaction Type)]
      
    
    
      
      
      Identification of the specific substance (or pharmaceutical product) considered to be
       responsible for the Adverse Reaction event. Note: the substance for a specific reaction
       may be different from the substance identified as the cause of the risk, but it must be
       consistent with it. For instance, it may be a more specific substance (e.g. a brand medication)
       or a composite product that includes the identified substance. It must be clinically safe
       to only process the 'code' and ignore the 'reaction.substance'.  If a receiving system
       is unable to confirm that AllergyIntolerance.reaction.substance falls within the semantic
       scope of AllergyIntolerance.code, then the receiving system should ignore AllergyIntolerance.reactio
      n.substance.
      Coding of the specific substance (or pharmaceutical product) with a terminology capable
       of triggering decision support should be used wherever possible.  The 'code' element allows
       for the use of a specific substance or pharmaceutical product, or a group or class of
       substances. In the case of an allergy or intolerance to a class of substances, (for example,
       &quot;penicillins&quot;), the 'reaction.substance' element could be used to code the specific
       substance that was identified as having caused the reaction (for example, &quot;amoxycillin&quot;).
       Duplication of the value in the 'code' and 'reaction.substance' elements is acceptable
       when a specific substance has been recorded in 'code'.
      
      
      
        
      
      
        
          
        
        
        
        
      
      
        
        outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code &lt;= ExposureCode].participation[ty
        peCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND, code &lt;=
         ExposureAgentEntityType]
      
    
    
      
      
      Clinical symptoms and/or signs that are observed or associated with the adverse reaction
       event.
      Manifestation can be expressed as a single word, phrase or brief description. For example:
       nausea, rash or no reaction. It is preferable that manifestation should be coded with
       a terminology, where possible. The values entered here may be used to display on an application
       screen as part of a list of adverse reactions, as recommended in the UK NHS CUI guidelines.
        Terminologies commonly used include, but are not limited to, SNOMED CT or ICD10.
      
      
      
      
      
        
      
      
        
          
        
        
        Clinical symptoms and/or signs that are observed or associated with an Adverse Reaction
         Event.
        
      
      
        
        
      
      
        
        
      
    
    
      
      

       within an Intensive Care Unit or under corticosteroid cover. The notes should be
       related to an allergy or intolerance as a condition in general and not related
       to any particular episode of it. For episode notes and descriptions, use AllergyIntolerance.e
      vent.description and  AllergyIntolerance.event.notes."/> 
      <min value="0"/>       <max value="*"/>       <type>         <code value="Annotation"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="subjectOf.observationEvent[code=&quot;annotation&quot;].value"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction">      <path value="AllergyIntolerance.reaction"/>       <short value="Adverse Reaction Events linked to exposure to substance"/>       <definition value="Details about each adverse reaction event linked to exposure to the identified

       substance."/> 
      <min value="0"/>       <max value="*"/>       <type>         <code value="BackboneElement"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SUBJ].target[classCode=OBS, moodCode=EVN, code &lt;=

         CommonClinicalObservationType, value &lt;= ObservationValue (Reaction Type)]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.reaction.substance">      <path value="AllergyIntolerance.reaction.substance"/>       <short value="Specific substance or pharmaceutical product considered to be responsible for event"/>       <definition value="Identification of the specific substance (or pharmaceutical product) considered

       to be responsible for the Adverse Reaction event. Note: the substance for a specific
       reaction may be different from the substance identified as the cause of the risk,
       but it must be consistent with it. For instance, it may be a more specific substance
       (e.g. a brand medication) or a composite product that includes the identified substance.
       It must be clinically safe to only process the 'code' and ignore the 'reaction.substance'.
        If a receiving system is unable to confirm that AllergyIntolerance.reaction.substance
       falls within the semantic scope of AllergyIntolerance.code, then the receiving
       system should ignore AllergyIntolerance.reaction.substance."/> 
      <comment value="Coding of the specific substance (or pharmaceutical product) with a terminology

       capable of triggering decision support should be used wherever possible.  The 'code'
       element allows for the use of a specific substance or pharmaceutical product, or
       a group or class of substances. In the case of an allergy or intolerance to a class
       of substances, (for example, &quot;penicillins&quot;), the 'reaction.substance'
       element could be used to code the specific substance that was identified as having
       caused the reaction (for example, &quot;amoxycillin&quot;). Duplication of the
       value in the 'code' and 'reaction.substance' elements is acceptable when a specific
       substance has been recorded in 'code'."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="CodeableConcept"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="SubstanceCode"/>         </extension>         <strength value="example"/>         <description value="Codes defining the type of the substance (including pharmaceutical products)."/>         <valueSet value="http://hl7.org/fhir/ValueSet/substance-code"/>       </binding>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code &lt;= ExposureCode].participa

        tion[typeCode=CSM].role[classCode=ADMM].player[classCode=MAT, determinerCode=KIND,
         code &lt;= ExposureAgentEntityType]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.reaction.manifestation">      <path value="AllergyIntolerance.reaction.manifestation"/>       <short value="Clinical symptoms/signs associated with the Event"/>       <definition value="Clinical symptoms and/or signs that are observed or associated with the adverse

       reaction event."/> 
      <comment value="Manifestation can be expressed as a single word, phrase or brief description. For

       example: nausea, rash or no reaction. It is preferable that manifestation should
       be coded with a terminology, where possible. The values entered here may be used
       to display on an application screen as part of a list of adverse reactions, as
       recommended in the UK NHS CUI guidelines.  Terminologies commonly used include,
       but are not limited to, SNOMED CT or ICD10."/> 
      <alias value="Symptoms"/>       <alias value="Signs"/>       <min value="1"/>       <max value="*"/>       <type>         <code value="CodeableReference"/>         <targetProfile value="http://hl7.org/fhir/StructureDefinition/Observation"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="Manifestation"/>         </extension>         <strength value="example"/>         <description value="Clinical symptoms and/or signs that are observed or associated with an Adverse

         Reaction Event."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/clinical-findings"/>       </binding>       <mapping>         <identity value="v2"/>         <map value="AL1-5"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="code"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.description">      <path value="AllergyIntolerance.reaction.description"/>       <short value="Description of the event as a whole"/> 
      <definition value="Text description about the reaction as a whole, including details of the manifestation
       if required.
      Use the description to provide any details of a particular event of the occurred reaction
       such as circumstances, reaction specifics, what happened before/after. Information, related
       to the event, but not describing a particular care should be captured in the comment field.
       For example: at the age of four, the patient was given penicillin for strep throat and
       subsequently developed severe hives.
      
      
      
      
      
        
      
      
        
        
      
    
    
      
      
      
      
      
      
        
      
      
        
        
      
      
        
        
      
    
    
      
      
      Clinical assessment of the severity of the reaction event as a whole, potentially considering
       multiple different manifestations.

       if required."/> 
      <comment value="Use the description to provide any details of a particular event of the occurred

       reaction such as circumstances, reaction specifics, what happened before/after.
       Information, related to the event, but not describing a particular care should
       be captured in the note field. For example: at the age of four, the patient was
       given penicillin for strep throat and subsequently developed severe hives."/> 
      <alias value="Narrative"/>       <alias value="Text"/>       <min value="0"/>       <max value="1"/>       <type>         <code value="string"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="text"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.onset">      <path value="AllergyIntolerance.reaction.onset"/>       <short value="Date(/time) when manifestations showed"/>       <definition value="Record of the date and/or time of the onset of the Reaction."/>       <min value="0"/>       <max value="1"/>       <type>         <code value="dateTime"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="v2"/>         <map value="AL1-6"/>       </mapping>       <mapping>         <identity value="rim"/>         <map value="effectiveTime.low"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.severity">      <path value="AllergyIntolerance.reaction.severity"/>       <short value="mild | moderate | severe (of event as a whole)"/>       <definition value="Clinical assessment of the severity of the reaction event as a whole, potentially

       considering multiple different manifestations."/> 

      <comment value="It is acknowledged that this assessment is very subjective. There may be some specific
       practice domains where objective scales have been applied. Objective scales can be included
       in this model as extensions.
      
      
      
        
      
      
        
          
        
        
        Clinical assessment of the severity of a reaction event as a whole, potentially considering
         multiple different manifestations.
        
      
      
        
        inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV, value
         &lt;= SeverityObservation (Severity Level)]
      
    
    
      
      
      
      
      
      
      
        
      
      
        
          
        
        
        A coded concept describing the route or physiological path of administration of a therapeutic
         agent into or onto the body of a subject.
        
      
      
        
        
      
    
    
      
      
      
      Use this field to record information indirectly related to a particular event and not
       captured in the description. For example: Clinical records are no longer available, recorded
       based on information provided to the patient by her mother and her mother is deceased.
      
      
      
        
      
      
        
        
      
    
  

       practice domains where objective scales have been applied. Objective scales can
       be included in this model as extensions."/> 
      <min value="0"/>       <max value="1"/>       <type>         <code value="code"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="AllergyIntoleranceSeverity"/>         </extension>         <strength value="required"/>         <description value="Clinical assessment of the severity of a reaction event as a whole, potentially

         considering multiple different manifestations."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/reaction-event-severity|6.0.0-ballot3"/>       </binding>       <mapping>         <identity value="rim"/>         <map value="inboundRelationship[typeCode=SUBJ].source[classCode=OBS, moodCode=EVN, code=SEV,

         value &lt;= SeverityObservation (Severity Level)]"/> 
      </mapping>     </element>     <element id="AllergyIntolerance.reaction.exposureRoute">      <path value="AllergyIntolerance.reaction.exposureRoute"/>       <short value="How the subject was exposed to the substance"/>       <definition value="Identification of the route by which the subject was exposed to the substance."/>       <comment value="Coding of the route of exposure with a terminology should be used wherever possible."/>       <min value="0"/>       <max value="1"/>       <type>         <code value="CodeableConcept"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <binding>         <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">          <valueString value="RouteOfAdministration"/>         </extension>         <strength value="example"/>         <description value="A coded concept describing the route or physiological path of exposure to a substance."/>         <valueSet value="http://hl7.org/fhir/ValueSet/route-codes"/>       </binding>       <mapping>         <identity value="rim"/>         <map value="outBoundRelationship[typeCode=SAS].target[classCode=SBADM, code &lt;= ExposureCode].routeCode"/>       </mapping>     </element>     <element id="AllergyIntolerance.reaction.note">      <path value="AllergyIntolerance.reaction.note"/>       <short value="Text about event not captured in other fields"/>       <definition value="Additional text about the adverse reaction event not captured in other fields."/>       <comment value="Use this field to record information indirectly related to a particular event and

       not captured in the description. For example: Clinical records are no longer available,
       recorded based on information provided to the patient by her mother and her mother
       is deceased."/> 
      <min value="0"/>       <max value="*"/>       <type>         <code value="Annotation"/>       </type>       <mustSupport value="false"/>       <isModifier value="false"/>       <isSummary value="false"/>       <mapping>         <identity value="rim"/>         <map value="subjectOf.observationEvent[code=&quot;annotation&quot;].value"/>       </mapping>     </element>   </differential> 


</

StructureDefinition

>



doc2=http%3A%2F%2Fhl7.org%2Ffhir%2FR4

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.